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Cilzec 20 belongs to the class of angiotensin II receptor antagonists with the main ingredient telmisartan, commonly used to treat hypertension as monotherapy or in combination with other antihypertensive agents. So what is Cilzec 20?
1. What are the effects of Cilzec 20?
What is Cilzec 20 drug? Cilzec 20 has the main ingredient telmisartan, a specific antagonist of the angiotensin II receptor, used in the treatment of hypertension caused by cardiovascular disease. After taking the first dose of telmisartan, the antihypertensive effect will come gradually and become apparent within 3 hours. The antihypertensive effect reached a maximum after 4 weeks of treatment and was maintained during long-term treatment. In hypertensive patients, telmisartan has been shown to reduce both systolic and diastolic blood pressure without affecting heart rate. Upon discontinuation of treatment with telmisartan, blood pressure gradually returned to pre-treatment values over several days without rebound hypertension.
Treatment with telmisartan has also been shown to significantly reduce left ventricular weight and left ventricular mass index in hypertensive patients with left ventricular hypertrophy. Cilzec 20 is often indicated in cases of essential hypertension. However, the drug Cilzec 20 is contraindicated in the following subjects:
Patients with hypersensitivity to any component of the drug Cilzec 20 Pregnant women in the second or third trimester of pregnancy Breast-feeding women Patients with liver failure , cholestasis
2. Dosage of the drug Cilzec 20
Cilzec 20 is usually taken orally, patients can take it with or without food. The specific dose of Cilzec 20 depends on the subjects and treatment goals, specifically as follows:
Adults: 40 mg x 1 time / day, the dose can be increased to 80 mg / day Use as monotherapy or in combination with thiazide diuretics No dose adjustment is required for Cilzec 20 in the elderly or in patients with renal impairment For patients with mild to moderate hepatic impairment, a dose of 40 mg/day should be noted: Safety and efficacy in children children have not been established, so use is not recommended for young children.
3. Side effects of the drug Cilzec 20
In some patients when using Cilzec 20 may experience the following side effects:
Urinary tract infections Upper respiratory tract infections Mental disorders Vision disorders Labyrinth and ear disorders Dizziness Disorders gastrointestinal: abdominal pain, diarrhea, dry mouth, indigestion, flatulence Skin and subcutaneous tissue disorders Joint pain, back pain, leg cramps, leg pain, muscle pain, tendinitis-like symptoms Chest pain, flu-like symptoms
4. Be careful when using Cilzec 20
Some general precautions when using Cilzec 20 include:
Caution should be taken when using telmisartan in patients with biliary obstruction or liver failure, because most of the drug is eliminated via the bile, so clearance of the drug is reduced in those patients. In this patient Cilzec 20 acts on the renin-angiotensin-aldosterone system and may alter renal function in susceptible patients. In volume- or salt-depleted patients, hypotension may occur shortly after Initiate treatment with telmisartan tablets. Therefore, it is necessary to correct these abnormalities before starting treatment with telmisartan or to reduce the dose of telmisartan and initiate treatment under close medical supervision. In the presence of hypotension, the patient should be placed on the supine position and intravenous infusion with normal saline if necessary There is no clinical experience with the use of telmisartan tablets in pregnancy.
5. Drug interactions with Cilzec 20
Concomitant administration of telmisartan with digoxin may increase digoxin peak plasma concentrations and trough concentrations. Therefore, it is necessary to monitor digoxin levels at the start of treatment, when adjusting the dose or stopping telmisartan to avoid insufficient or overdosage of digoxin. Co-administration of Cilzec 20 with warfarin may increase mean trough concentrations but not change the international normalized ratio. Cilzec 20 belongs to the class of angiotensin II receptor antagonists with the main ingredient telmisartan, commonly used to treat hypertension as monotherapy or in combination with other antihypertensive agents. To ensure the effectiveness of treatment and avoid unwanted side effects, patients need to strictly follow the instructions of the doctor, professional pharmacist.
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