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Ciclevir 800 is commonly prescribed by doctors to treat infections with Herpes simplex virus and Varicella-zoster virus. Ciclevir 800 will work optimally if used correctly by the patient and at the dose recommended by the doctor.1. What is Ciclevir 800?
Ciclevir 800 belongs to the group of antifungal, antiviral, anti-infective and anti-parasitic drugs. Ciclevir 800 is manufactured by Glomed Pharmaceutical Joint Stock Company, commonly recommended by doctors for cases of herpes simplex virus types 1 and 2 in the mucous membranes and skin, including genital herpes.Ciclevir 800 is prepared in the form of tablets, packed in boxes of 3 blisters or 5 blisters x 10 tablets. The main ingredient in the drug Ciclevir 800 is the active ingredient Aciclovir with the strength of 800mg and a combination of other excipients just enough.
2. What are the effects of Ciclevir 800?
2.1. Uses of Ciclevir 800
The active ingredient Aciclovir in Ciclevir 800 is known to be a synthetic purine nucleoside analogue, which is active against Herpes simplex virus types 1, 2 and Varicella-zoster virus (Zona - chickenpox). The antiviral activity of aciclovir is based on intracellular conversion to the aciclovir monophosphate form via the viral thymidine kinase. Aciclovir monophosphate is then further converted to aciclovir triphosphate and aciclovir monophosphate by cellular enzymes.Metabolized form Aciclovir triphosphate has the ability to inhibit the synthesis and replication of viral DNA by inhibiting the Herpes virus DNA polymerase enzyme, which then binds to their DNA. This process is usually highly selective for infected cells.
Ciclevir 800 is most effective against herpes simplex virus type 1, followed by type 2 and finally shingles virus - chickenpox. When administered to humans, aciclovir will reach peak plasma concentrations 1.5-2 hours after oral administration. On the other hand, the absorption of Aciclovir is not affected by food.
2.2. Indications to use Ciclevir 800
Ciclevir 800 is usually prescribed by doctors for the following specific cases:Initial treatment and prevention of reinfection with Herpes simplex virus types 1 and 2 in mucous membranes or skin, including genital herpes. . Treatment of acute Herpes zoster virus infection (shingles), Herpes zoster pneumonia in adults or Shingles of the eye. Initial treatment and prevention of reinfection with Herpes simplex in immunocompromised or immunocompromised patients. Treatment of hemorrhagic varicella conditions, neonatal varicella and varicella in immunocompromised individuals.
2.3. Contraindications to the use of Ciclevir 80
Do not use Ciclevir 800 medicine for the following cases without a prescription from a specialist:Patients with a history of hypersensitivity or allergy to the active ingredient Aciclovir or any of the excipients in the drug. Ciclevir 800 is contraindicated in patients with anuria or renal failure. Relative contraindications Ciclevir 800 for pregnant women or nursing mothers.
3. Dosage and instructions for using Ciclevir 800
3.1. Dosage of Ciclevir 800
Below is the dose of Ciclevir 800 as recommended by the doctor, specifically:Treatment of Herpes simplex virus infections Dose for children over 2 years old and adults: Take 200mg / time and 400mg / time for patients with impaired severe immunosuppression. Take the drug 5 times a day and each dose is about 4 hours apart. Patients should take Ciclevir 800 continuously for 5-10 days. Dose for children under 2 years: Take 1/2 adult dose of Ciclevir 800. Herpes simplex prophylaxis: Dose for patients with normal immune response: Oral 800mg/day x 2-4 times/day. Dose for immunocompromised patients: Take 200-400mg/time x 4 times/day (adults and children over 2 years old) or take 1/2 dose of adults (children under 2 years old). Treatment of chickenpox: Dose for adults: Take 800mg/time x 4-5 times/day and use within 5-7 days. Dose for children over 6 years old: Take 800mg/time x 4 times/day. Dose for children from 2 to 5 years old: 400mg/time x 4 times/day. Dose for children under 2 years old: 200mg/time x 4 times/day. Treatment of shingles: Dose for children over 2 years old and adults: Take 800mg/time x 5 times/day, use within 7-10 days. Dose for children under 2 years: Take 1/2 adult dose. Dosage of Ciclevir 800 for patients with renal failure (creatinine clearance < 10ml / min): Treatment of Herpes simplex infections: 200mg/time, each dose is about 12 hours apart. Treatment of infection with shingles - chickenpox: Take 800mg / time x 3 times / day, each dose is about 8 hours apart.
3.2. Instructions for using Ciclevir 800
Ciclevir 800 is in the form of a tablet, so it will be taken orally. Patients should take the drug with meals to reduce the effect of the drug on the gastrointestinal tract.When taking Ciclevir 800, you should swallow the tablet whole, avoid crushing or chewing it because this may affect the effect of the active ingredients in the medicine. According to the doctor's recommendation, the drug Ciclevir 800 should be taken as soon as possible, the drug will work optimally when used at the beginning of the infection.
3.3. How to deal with an overdose of Ciclevir 800
Ciclevir 800 when taken in excess of the recommended dose can cause noticeable symptoms such as coma, convulsions, agitation or lethargy. Aciclovir may occasionally precipitate in the renal tubules if the tubular fluid concentration exceeds the solubility by about 2.5 mg/ml.To handle the overdose of Ciclevir 800, the doctor will conduct an examination and select appropriate treatment measures for the patient. For patients with acute renal failure or anuria, hemodialysis will be applied until kidney function recovers.
4. Possible side effects when using Ciclevir 800
During the treatment of Herpes simplex virus infections, shingles and chickenpox with Ciclevir 800, patients may inadvertently experience the following side effects:Short-term use of Ciclevir 800 can make people sick. side effects of nausea or vomiting. Long-term use of Ciclevir 800 may cause symptoms such as nausea, vomiting, abdominal pain, diarrhea, headache or skin rash. Patients should stop taking Ciclevir 800 and consult their doctor if side effects do not go away, get worse, or even develop new unusual symptoms.
5. Things to note and caution when using Ciclevir 800
5.1. What precautions should be taken while using Ciclevir 800?
Here are some things that patients should be cautious of during treatment with Ciclevir 800:Ciclevir should be used with caution in patients with renal impairment, dosage adjustment may be considered based on clearance. creatinine clearance. A slow intravenous infusion over 1 hour may be used to prevent the risk of aciclovir precipitation in the kidney. Avoid injecting large amounts or injecting quickly. The risk of renal failure is increased if the patient is taking concomitantly with nephrotoxic drugs. Ciclevir 800 should be used during pregnancy only if the potential benefits outweigh the risks to the fetus. Ciclevir 800 may be excreted in breast milk when administered orally. Therefore, people who are breast-feeding should be cautious and consult their doctor carefully before deciding to use Ciclevir 800. Caution should be taken when using Ciclevir 800 to drive or frequently operate machinery because the drug can have harmful effects. May cause side effects such as headache. Store the medicine in a cool, dry place, away from direct sunlight and high humidity. Check the expiry date of Ciclevir 800 before using it to avoid taking expired medicine. Check the color, shape and texture of Ciclevir 800 before taking it.
5.2. Does Ciclevir 800 interact with other drugs?
Some drugs may interact with Ciclevir 800 together, including:Zidovudine combined with Ciclevir easily causes drowsiness and lethargy. Probenecid competitively inhibits the renal tubular elimination of the active ingredient aciclovir. Ketoconazole and Amphotericin B may increase the antiviral activity of Aciclovir. Interferon or Methotrexate
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