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Cetrotide is indicated to prevent premature ovulation. So how should Cetrotide be used? What precautions should be taken when using this drug? Let's find out the necessary information about the drug Cetrotide through the article below.
1. What is Cetrotide?
Ingredients: Cetrotide medicine contains the main ingredient is Cetrorelix 0.25 mg and excipients just enough.
Dosage form: The drug is prepared in powder form for solution for injection.
Manufacturer: Baxter Oncology GmbH - Germany.
Package: Box of 7 trays, each tray contains 1 vial of powder + 1 tube of 1 ml solvent.
2. Uses of the drug Cetrotide
2.1 Cetrotide Effects Cetrorelix is an injectable gonadotropin-releasing hormone (GnRH) antagonist, used in assisted reproduction to inhibit premature luteinizing hormone. Mechanism of action: blocks the action of GnRH on the pituitary gland, thereby rapidly inhibiting the production and activity of luteinizing hormone (LH) and follicle-stimulating hormone.
2.2 Indications Cetrotide is used in adjunctive treatment for prevention of premature ovulation in cases of both ovulation induction or controlled ovarian stimulation.
3. Dosage - How to take Cetrotide
Dosage:
Dosage: 0.25 mg per day, equivalent to 1 vial, divided into 1 time a day. Need to treat for a minimum period of 10 days
How to use:
Cetrotide is prepared in powder form for solution for injection, so patients use the drug by injection. Use Cetrotide in the morning or evening. Closely monitor the patient for 30 minutes after injecting Cetrotide. During the use of Cetrotide, patients need to follow the doctor's instructions, do not arbitrarily adjust the dose of Cetrotide to achieve their own desires.
4. Missed dose, overdose and treatment
Missed 1 dose:
If the patient forgets to take Cetrorelix for a day, consult a doctor immediately. It is best to take Cetrorelix 24 hours apart. But if you forget to take Cetrorelix at the right time, it shouldn't be a problem to take it at a different time of the day. Overdosage:
Overdosage in humans may lead to a prolonged duration of action but is unlikely to be associated with acute toxicity. Therefore, in case of overdose Cetrorelix does not require any specific measures. In the acute toxicity study in rodents, nonspecific symptoms of toxicity were observed following intraperitoneal administration of cetrorelix at doses 200 times the pharmacologically effective dose following subcutaneous administration.
5. Side effects of the drug Cetrotide
Common:
Shortness of breath, swelling of the throat. Swelling of lips, tongue, face. Various erythema. Itchy. Uncommon:
Ovarian hyperstimulation syndrome: pelvic pain, limb swelling, abdominal pain, dyspnea, weight gain, gastrointestinal disturbances (nausea, vomiting, diarrhea). Injection site irritation: redness, bruising, swelling at the injection site. Dizziness, dizziness, headache. During the use of the drug, if the patient experiences the above-mentioned side effects or any unusual symptoms, they should go to the nearest medical facility center to receive the advice of the doctor. therapist, consultant pharmacist and medical staff.
Accurate advice to avoid drug interactions that are not beneficial to the patient.
6. Notes when using the drug Cetrotide
Contraindications:
Do not use Cetrotide for people with a history of hypersensitivity to any of the ingredients in the drug. Pregnant and lactating women. Contraindicated in patients with impaired liver and kidney function. Do not treat with this medicine in postmenopausal women. Notes and cautions:
Patients should pay attention to a number of cases when using the drug as follows: Please check the expiration date carefully before using the medicine. Only use the drug when it is observed that the drug is intact, not denatured. Cetrotide should be used as soon as the bag is opened to avoid foreign invaders. Patients should not arbitrarily stop taking Cetrotide but must discuss and consult with the doctor or pharmacist directly prescribing the treatment. Use regularly and at the right dose for the best results. Cetrotide has no or negligible influence on the ability to drive and use machines. Caution for use on pregnant women and nursing mothers
Cetrotide is contraindicated in pregnant women and nursing mothers.
7. Drug interactions
During the study, there was no interaction between Cetrotide and other drugs such as drugs metabolized in the liver by cytochrome 450 or drugs conjugated with glucuronic. It is recommended to mix with aqueous solution for injection. Patients should minimize the amount of food or drink containing alcohol or stimulants. Patients should fully list the treatment drugs, vitamins, herbs, supporting pills and functional foods they are using recently so that doctors and pharmacists can know and advise. The article has provided information on what Cetrotide is used for, dosage and precautions for use. To ensure safety for your health and maximize the effectiveness of your treatment, you need to take Cetrotide exactly as directed by your doctor. Store Cetrotide in a cool, dry place, at a temperature not exceeding 30 degrees Celsius and out of the reach of small children.
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