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Cefurovid 250 is prepared in the form of film-coated tablets, with the main ingredient being Cefuroxime. The drug is used in the treatment of infections caused by susceptible bacteria.
1. Uses of the drug Cefurov 250
Cefuroxime 250mg medicine has the main ingredient is Cefuroxime 250mg. Cefuroxime is a cephalosporin antibiotic. Cefuroxime axetil is a precursor, does not have antibacterial effect, when it enters the body, it is hydrolyzed to cefuroxime to be effective. Cefuroxime ingredient has bactericidal effect during the period of bacterial growth and division (by inhibiting bacterial cell wall synthesis, weakening cell wall, unstable under osmotic pressure). .
Indications for the use of Cefurovid:
Treatment of upper respiratory tract infections: Ear - nose - throat infections such as sinusitis, pharyngitis, tonsillitis; Treatment of lower respiratory tract infections: Acute bronchitis, pneumonia, acute exacerbations of chronic bronchitis; Treatment of urinary - genital infections: cystitis, urethritis, nephritis - pyelonephritis; Treatment of skin and soft tissue infections: Purulent skin diseases, boils, impetigo; Treatment of uncomplicated acute urethritis (caused by gonorrhea), gonorrhea and cervicitis; Treatment of early Lyme disease, prevention of late stage Lyme disease in adults and children over 12 years of age. Contraindications to the use of Cefurovid 250:
People with a history of allergy to cephalosporin antibiotics or other components of the drug; People who are allergic to β-lactam antibiotics such as monobactam, penicillin, carbapenem.
2. How to take and dose of Cefurvid
Usage: Orally. The medicine should be taken with meals.
Dosage:
Dosage for people 12 years and older:
Ear - nose - throat infections: Take 250mg or 500mg every 12 hours, treat for 10 days; Lower respiratory tract infections: Take 250mg or 500mg every 12 hours, treat for 10 days (if exacerbation of chronic bronchitis) and treat for 5-10 days (if acute bronchitis with superinfection). ); Community-acquired pneumonia (outpatient treatment): Take 500mg every 12 hours, treat for 10-14 days; Uncomplicated urinary tract infections, soft tissue and skin infections: Take 250mg or 500mg every 12 hours, treat for 10 days; New Lyme disease: 250mg or 500mg every 12 hours, treat for 20 days. Dosage for other subjects:
Children 6 - 12 years old: Ear, nose and throat infections, dose of 250mg every 12 hours, treatment for 10 days; Children 3 months - 6 years old: Do not use drugs for this dosage form, use other dosage forms with more suitable concentrations; Children under 3 months of age: There are no studies on the use of drugs for this group of subjects; Elderly: No dose adjustment is required if the elderly have normal renal function. If the patient has impaired renal function, the dose should be adjusted accordingly; Patients with renal impairment: Safety and efficacy have not been established in this patient population. Since Cefuroxime is mainly eliminated by the kidneys, the dose of Cefuroxime should be reduced in patients with impaired renal function. Dosage of the drug is adjusted according to the patient's creatinine clearance (as prescribed by the doctor); Patients with hepatic impairment: There are no studies on the use of this drug in this group of patients. Missed dose: If you forget to take a dose of Cefurovid 250, the patient should take it as soon as possible. But if it is almost time for your next dose, skip the missed dose and just take your next dose as scheduled.
Overdose: When Cefurovid 250 is used in overdose, patients have nausea, vomiting, diarrhea, neuromuscular hyperexcitability and convulsions (common in patients with renal failure). In case of overdose, the patient should immediately go to the nearest medical facility for timely treatment. Treatment includes: Respiratory protection, ventilation support, and intravenous fluids. If convulsions are detected, the drug should be discontinued immediately and anticonvulsant therapy used if clinically indicated. Much of the treatment is supportive, resolving symptoms (although hemodialysis can remove drugs from the blood).
3. Side effects of the drug Cefurov 250
Some side effects patients may encounter when using Cefurovid 250 include:
Common: Diarrhea, skin rash; Uncommon: Anaphylaxis, Candida infection, eosinophilia, neutropenia, leukopenia, positive Coombs test, nausea, vomiting, urticaria, skin pruritus; Rare: Fever, anaemia, pseudomembranous colitis, toxic epidermal necrolysis, erythema multiforme, Stevens-Johnson syndrome, cholestatic jaundice, mild elevation of liver enzymes (AST, ALT, alkaline phosphatase, LDH), transient elevation of serum bilirubin, acute renal failure, interstitial nephritis, increased serum creatinine, uremia, renal pain, urinary tract infection, urethral pain or bleeding, vaginitis , difficulty urinating, vaginal itching and irritation, vaginal candidiasis, convulsions (if taking high doses and kidney failure), agitation, headache, joint pain,... When experiencing side effects of the drug Cefurov, the patient should immediately notify the doctor for appropriate advice and treatment.
4. Be careful when taking Cefurovid 250
Some notes for patients to remember before and while using Cefurovid:
Caution when using the drug in people with a history of hypersensitivity to cephalosporins, penicillins or other drugs; When using the drug, patients may have hypersensitivity reactions with manifestations: fever, pruritus, skin redness, urticaria, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis syndrome, edema pulse , even anaphylactic reactions; Use caution when using the drug if the patient is allergic to beta-lactam antibiotics; Renal function should be checked in critically ill patients receiving maximum antibiotic doses; Caution when co-administering Cefurovid with potent diuretics, aminoglycoside antibiotics and cephalosporins; Long-term use of Cefurovid can cause superinfection; Cefurovid can cause pseudomembranous colitis, so it should be used with caution in patients with a history of gastrointestinal disease (especially those who have had colitis); Cefurovid can cause seizures, especially in patients with impaired renal function, not adjusted to reduce antibiotic dose. During the course of treatment, if convulsions occur, the drug should be discontinued and appropriate anti-epileptic drugs used; Safety and efficacy of cefuroxime axetil have not been established in pediatric patients under 3 months of age; Cefurov may affect the results of some laboratory tests; Use caution when using Cefurovid in pregnant and lactating women, only when absolutely necessary (with a doctor's prescription); Be careful when driving or operating machinery if you are already taking Cefurovid because it can cause side effects such as headache and dizziness.
5. Drug interactions Cefurov 250
Some drug interactions of Cefurovid include:
Concomitant use of Cefurovid with high doses of Probenecid will reduce renal clearance of cefuroxime and increase plasma concentrations of cefuroxime; Concomitant use of cefuroxime with aminoglycoside antibiotics, cephalothins (first generation cephalosporins) or potent diuretics (eg, furosemide) may increase nephrotoxicity; Cefuroxime axetil taken orally can affect the intestinal microflora, reduce estrogen reabsorption, leading to a decrease in the effectiveness of oral contraceptives containing progesterone and estrogen; Concomitant administration of Cefurovid with oral anticoagulants may increase blood clotting time. When using Cefurovid 250, patients should absolutely follow all instructions given by their doctor about dosage and how to use the drug. If there are any unusual symptoms, the patient should immediately notify the doctor for appropriate intervention.
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