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Cefdifort Cap has the main active ingredient: Cefradine 500mg and other excipients in a sufficient amount. This is a 1st generation Cephalosporin antibiotic that is used in the treatment of skin infections, urinary tract infections,...
1. What is Cefdifort Cap?
Cefdifort Cap has the main active ingredient: Cefradine 500mg and other excipients in a sufficient amount. This is a 1st generation Cephalosporin antibiotic that is used in the treatment of skin infections, urinary tract infections, ...
Cefdifort Cap is made in capsule form, suitable for oral use. direct.
1.1. Pharmacodynamics of the active ingredient Cefradine The main drug Cefradine is a first generation Cephalosporin antibiotic.
1.2. Pharmacokinetics of the active ingredient Cefradine Absorption: The main active ingredient Cefradine is well absorbed from the gastrointestinal tract and parenteral route. After an oral dose of 500mg, about 1 to 2 hours, the drug reaches a maximum blood concentration of about 15-120 mcg/ml. Distribution: The main drug Cefradine is widely distributed throughout the body, through the placenta and breast milk, but rarely through the cerebrospinal fluid. Metabolism: Cefradine is not metabolized in the body. Elimination: Cefradine is eliminated mainly in the urine, with a mean half-life of 1-1.5 hours. 1.3. The effect of the active ingredient Cefradine Cefradine drug has a medium spectrum of activity, effective against Gram-positive bacteria such as staphylococcus, streptococcus, pneumococcus (except methicillin-resistant streptococcus). The drug is also active against some specific gram-negative bacteria such as E.coli, Klebsiella pneumoniae, Proteus mirabilis and Shigella. Resistant strains: methicillin-resistant Staphylococcus, Enterobacter, indole-positive Proteus, Pseudomonas aeruginosa, Bacteroides, Enterococcus.
2. What disease does Cefdifort Cap treat?
Cefdifort Cap is used in the treatment of specific pathologies as follows:
Skin and skin structure infections, respiratory tract infections (except lobar pneumonia), urinary tract infections without complications. Severe urinary tract infections (including prostatitis) and lobar pneumonia. Middle ear infections caused by Influenzae infection.
3. Usage and dosage of Cefdifort Cap
3.1. How to take Cefdifort Cap Cefdifort Cap is prepared in the form of film-coated tablets, suitable for direct oral use.
3.2. Dosage of Cefdifort Cap Dosage for treatment of skin and skin structure infections, respiratory tract infections (except lobar pneumonia), uncomplicated urinary tract infections, the dose is 500 mg x 2 times/day. Dosage for severe urinary tract infections (including prostatitis) and lobar pneumonia is 500 mg x 4 times/day or 1 g x 2 times/day. Dosage for children over 9 months old is 25-50 mg/kg/day, divided into 2 to 4 times. Dosage for treatment of otitis media caused by Influenzae is 75-100 mg/kg/day, divided into 2 to 4 times, up to 4g/day. Dosage for patients with renal impairment: reduce dose according to ClCr.
4. Undesirable effects of Cefdifort Cap
In addition to the therapeutic effects of the drug, during treatment with Cefdifort Cap, there may also be some unwanted effects, specifically as follows:
Digestive disorders, intestinal inflammation, syndromes Lyell, increased liver enzymes, changes in hematological indicators, changes in kidney function, pneumonia, PIE syndrome, superinfection, vitamin K and B deficiency. Occurrence of hallucinations, headache, dizziness, tired. The above does not include all the adverse effects and other side effects that may also occur during use. You need to pay attention to proactively notify your treating doctor for appropriate medical advice about adverse effects when using Cefdifort Cap.
5. Interactions of Cefdifort Cap
Interactions of drugs Cefdifort Cap: When used concurrently with nephrotoxic drugs such as aminosides, furosemide, ethacrynic acid... will increase nephrotoxicity. Concomitant use of Cefdifort Cap with Probenecid slows the elimination, thereby prolonging the action of the main active ingredient Cefradin. You need to take the initiative to inform your treating doctors or clinical pharmacists about all kinds of herbal products or health foods, prescription and over-the-counter medicines. that you are using to minimize adverse drug interactions that may cause unwanted effects on the health of the user. Interactions of Cefdifort Cap with food and drinks: When using this drug with foods or alcohol, beer, tobacco, etc., because foods and drinks contain other active ingredients. may cause antagonism or synergistic effects with the drug. You need to actively read the instructions for use of this medicine or consult your doctor about how to use Cefdifort Cap with foods, drinks containing alcohol or smoking.
6. Some notes when using Cefdifort Cap
6.1. Contraindications of the drug Cefdifort Cap People who are allergic to Cephalosporin antibiotics. Contraindications of the drug Cefdifort Cap are absolute contraindications, that is, in any case, these contraindications cannot be flexible in the treatment of disease with this drug. To ensure the effectiveness of the treatment process, it is best for the user of the drug to strictly follow the instructions of the treating doctor about the dose and how to use the drug. 6.2. Cefdifort Cap should be used with caution in people with a history of hypersensitivity to penicillin antibiotics, a personal or family history of allergies, and people with severe kidney disease. Elderly people who are physically exhausted. 6.3. Use of Cefdifort Cap in Pregnancy and Lactation Pregnancy: Although Cefdifort Cap has no effect on pregnancy, perinatal and postnatal development in animals at various dose levels was tolerated in the mother animal, safety in human pregnancy has not been established. Therefore, Cefdifort Cap should not be used during pregnancy unless absolutely necessary and the benefits outweigh the risks. Lactation: Cefdifort Cap is excreted in the milk of rats. Currently there are no data in humans, there is a risk that Cefdifort Cap is also excreted in human milk, so mothers being treated with this drug should not breast-feed. 6.4. Effects of Cefdifort Cap on Drivers and Machine Operators Caution should be taken when using Cefdifort Cap while driving or operating machinery, because the drug can cause side effects such as headache, dizziness, fatigue. fatigue, hallucinations. Store Cefdifort Cap in a dry place, the temperature is below 30 degrees Celsius in tightly closed containers, avoid places with high humidity and avoid direct sunlight. Besides, it is necessary to store Cefdifort Cap medicine out of the reach of children and family pets. Absolutely do not use Cefdifort Cap when it has expired, watery, distorted, or shows signs of color change or substance, musty smell. Consult with environmental protection companies for how to dispose of drugs. Absolutely do not throw or flush the medicine down the toilet or water pipes. Cefdifort Cap has the main active ingredient: Cefradine 500mg and other excipients in a sufficient amount. This is a 1st generation Cephalosporin antibiotic used in the treatment of skin infections, urinary tract infections. When prescribed by a treating doctor, patients should carefully read the instructions for use, consult a doctor or clinical pharmacist before using the drug. Absolutely do not arbitrarily buy Cefdifort Cap to treat diseases at home, because there may be unwanted side effects to health.
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