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Cedex is a medicine to treat cough with phlegm, cough due to allergies, respiratory irritation. Cedex contains 3 main active ingredients: Guaifenesin 100mg; Cetirizine hydrochloride 5mg; Dextromethorphan hydrobromide 15mg. Learn how to use Cedex in the article below.
1. What is Cedex?
Cedex drug with main ingredient is Guaifenesin 100mg; Cetirizine hydrochloride 5mg; Dextromethorphan hydrobromide 15mg. Guaifenesin has an expectorant effect by irritating the gastric mucosa, then increasing secretions in the respiratory tract, increasing the volume and reducing the viscosity of secretions. As a result, the drug increases the effectiveness of the cough reflex and makes it easier to expel sputum. The drug is indicated for the treatment of cough with thick, thick sputum that is difficult to expel due to colds, mild upper respiratory tract infections. The drug is often combined with bronchodilators, nasal decongestants, antihistamines, cough suppressants. Cetirizine hydrochloride: potent and selective antagonist at peripheral H1 receptors, certirizine inhibits the early stages of histamine-mediated allergic reactions and reduces the release of mediators in the late stages of allergic reactions. response. Dextromethorphan hydrobromide: is a cough suppressant that acts on the cough center in the medulla oblongata, has no analgesic effect and generally has little sedative effect. It is used to relieve cough caused by mild irritation of the bronchi and throat such as the common cold or inhalation of irritants. The drug does not have an expectorant effect, so it is most effective in the treatment of chronic cough without phlegm.
2. Uses of the drug Cedex
Cedex is indicated in the treatment of: Cough with phlegm, cough due to throat and bronchial irritation caused by the common cold or cough due to allergies, due to inhalation of respiratory irritants.
Cedex is contraindicated in the following subjects:
People who are sensitive to Guaifenesin; Cetirizine hydrochloride; Dextromethorphan hydrobromide or any of its ingredients. Pregnant and lactating women. Children under 4 years of age The disease is using monoamine oxidase inhibitors (MAO) because it can cause severe reactions such as high fever, dizziness, increased blood pressure, brain bleeding, even death. End stage renal failure.
3. Dosage of Cedex
Adults and children ≥ 6 years old: 1 tablet x 2 times/day. Children from 4 to 6 years old: 1 tablet/day. Some unwanted effects of Cedex drugs such as drowsiness, fatigue, dizziness, tachycardia, sore throat, flushing, dry mouth, headache, nausea, kidney stones (due to drug abuse).
4. Be careful when using Cedex
Each ingredient in Cedex can cause unwanted side effects if used incorrectly. Here are some cautions when taking medicine that patients should "lay down"
For Guaifenesin ingredients:
Do not use in cases of persistent or chronic cough such as in patients who smoke, have asthma, inflammation chronic bronchi, emphysema or cough with excessive phlegm. Drink plenty of water while taking the medicine. Do not self-medicate for more than 7 days without consulting your doctor. Guaifenesin is considered unsafe for use in patients with porphyria-induced porphyria in laboratory animals. Use in Children: Poisoning and potentially fatal overdoses have been reported with over-the-counter cough and cold preparations containing expectorants in young children. Therefore, do not arbitrarily use Guaifenesin for children under 4 years of age unless directed by a doctor. For ingredients Cetirizine hydrochloride:
Need to adjust the dose in people with moderate or severe renal impairment and people on hemodialysis. the drug's somnolence. Concomitant use of Cetirizine with alcohol and other CNS depressants should be avoided because this effect may be enhanced. For the ingredient Dextromethorphan hydrobromide:
Patients with cough with excessive phlegm, chronic cough in smokers People at risk or suffering from respiratory depression Be cautious with children with allergies Abuse and dependence Dextromethorphan can may occur (rarely) especially due to prolonged high doses of the drug. In addition, this drug is not used for pregnant women because there has not been a full study of the effects of the ingredients in the preparation on this subject. Certirizine is excreted in milk and should not be used in nursing women.
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