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Cadiferon drug is prepared in the form of soft capsules, with the main ingredients being folic acid, vitamin B12 and iron fumarate. The drug is used in the treatment of patients with a lack of hematopoietic material.
1. What are the effects of Cadiferon?
What is Cadiferon? 1 Cadiferon-F tablet contains: 0.75mg folic acid, 125mcg vitamin B12 and 162mg iron fumarate and other excipients. The ingredients in the drug have the following uses:
Folic acid: Is vitamin B9, belongs to group B vitamins, participates in the synthesis of DNA (because it synthesizes pyrimidine or purine nucleotides). At the same time, this ingredient also affects RNA synthesis and erythropoiesis; Vitamin B12: Is a blood-forming material and an essential factor for the development of small intestine and uterine tissue, ensuring nerve myelin is not destroyed; Iron fumarate: Is a component of the respiratory enzyme cytochrome C, the Hem nucleus of hemoglobin and myoglobin. What does Cadiferon do? The drug Cadiferon with the above 3 active ingredients plays an important role in the hematopoietic process. Iron is required for the production of myoglobin, hemoglobin and the respiratory enzyme cytochrome C. Normally, iron is absorbed in the duodenum and proximal jejunum. A normal person without iron deficiency will absorb about 0.5 - 1mg of elemental iron daily. If iron stores are low or iron requirements are increased, iron absorption is increased.
Total iron absorption is increased to 1 - 2 mg/day in menstruating women, up to 3 - 4 mg/day in pregnant women. Children and adolescents also have increased iron requirements during the period of strong growth. Folic acid, vitamin B12 in combination with iron play an important role in the prevention and treatment of megaloblastic anemia in pregnant women.
Indications for the use of Cadiferon drugs
Prevention of iron deficiency anemia in pregnant women, lactating mothers, women during menstruation, children at puberty; Supplemental iron, vitamin B12 and folic acid for cases of blood loss due to trauma, surgery, worm infection or blood donors. Contraindications to use Cadiferon
People with a history of hypersensitivity or allergy to any of the ingredients of the drug; Patients with malignancies or suspected malignancies; People with excess iron: Hemolytic anemia, iron-contaminated tissue disease, hemosiderin infection.
2. How to use and dose of Cadiferon
Usage: Orally. Patients should take the medicine in the morning, 1 hour before eating or about 2 hours after eating. Cadiferon should be taken with at least half a glass of water. When drinking, do not chew the tablet, but take the whole tablet with boiled water to cool.
Dosage: As directed by a doctor or for reference:
Adults: 1 tablet/time x 2 times/day; Children: 1 tablet/time/day; Pregnant women: 1 tablet/time since pregnancy is detected. Overdose: Manifestations when taking Cadiferon overdose are quite similar to side effects with manifestations such as nausea, vomiting, abdominal pain, diarrhea with blood, dehydration, shock with somnolence, infection acid,... There is a period of thinking of recovery when there are no symptoms, but after about 6-24 hours, symptoms such as coagulopathy and cardiovascular collapse appear. In addition, patients may experience hepatotoxicity or high fever, hypoglycemia, kidney failure, convulsions and coma.
Therefore, patients need to be closely monitored for facial expressions, skin, blood pressure and prevention because dangerous conditions can progress very quickly. It is best that when taking an overdose, the patient should immediately notify the doctor for timely treatment. The treatment is first gastric lavage with milk or carbonate solution. Then, inject deferoxamine solution to the patient. Use dopamine if necessary to raise blood pressure. If the patient has renal failure, consider hemodialysis. At the same time, it is necessary to adjust the balance of acid base and electrolytes, rehydrate the body.
Missed dose: Avoid forgetting a dose of Cadiferon. If a dose is missed, the patient should skip the missed dose and do not take the next dose. Patients should also not miss more than 2 doses in a row.
3. Side effects of the drug Cadiferon
When using Cadiferon, patients may experience side effects in the gastrointestinal tract such as discomfort, abdominal pain, nausea, vomiting and constipation,... If you suspect that you are taking medication, you should consult your doctor for timely and accurate treatment.
4. Be careful when using the drug Cadiferon
Some notes patients need to remember before and while taking Cadiferon:
Caution when using Cadiferon in pregnant and lactating women; The drug Cadiferon may be more dangerous for patients with malignancies, so caution should be exercised in this group of subjects; Cadiferon should not be taken with tea containing tannin, because large amounts of tea will inhibit iron absorption; During the time of taking Cadiferon, the patient should absolutely follow the doctor's instructions on the dose, avoid increasing or decreasing the dose to speed up the treatment time; Before discontinuing the use of Cadiferon, patients should consult their doctor.
5. Cadiferon drug interactions
During the use of Cadiferon, if the patient has to take one or more other drugs, these drugs may interact with each other, affecting the absorption, metabolism and excretion of Cadiferon. drugs, even reducing the effect or causing toxicity to the body.
Some drug interactions of Cadiferon include:
Avoid concomitant use with anticonvulsants such as zinc, antacids (calcium carbonate, sodium carbonate, magnesium trisilicate) or anticonvulsants (phenobarbital, phenytoin, primidone) ; Caution when combined with drugs: Quinolones, tetracyclines, penicillamine, methyldopa, thyroid hormones. Users should inform their doctors about the medicines and health foods that they are taking at the moment to avoid unintended drug interactions. In addition, users also need to inform their doctor about their medical history to make appropriate adjustments.
In summary, Cadiferon drug is made in the form of softgels, with the main ingredients being folic acid, vitamin B12 and iron fumarate. The drug is used in the treatment of patients with a lack of hematopoietic material. When prescribed to use Cadiferon, users should also strictly follow the doctor's instructions to ensure effective treatment and significantly limit the risk of some unwanted effects.
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