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Buscopan is an injectable medication that belongs to the group of spasmolytics. Buscopan medicine 20mg/ml is indicated in cases of gastrointestinal spasms, biliary tract spasms, renal colic and menstrual pain relief.1. What is Buscopan?
Buscopan has the main ingredient Hyoscin butylbromide - an antispasmodic agent. Medications work to relieve pain by acting on the muscles that cause pain.
Hyoscine butylbromide has an antispasmodic effect on smooth muscle of the stomach - intestines, biliary tract and urinary tract. This is a quaternary ammonium derivative that does not enter the central nervous system. Therefore, the drug has no anticholinergic side effects on the central nervous system, only peripheral anticholinergic effects.
Due to its high affinity for muscarinic receptors and nicotinic receptors (these receptors have a role in muscle contraction and relaxation), Buscopan is mainly distributed and acts on the muscles of the abdomen, pelvis and lymph nodes of the abdomen. organs in the abdomen.
After injection, the drug is excreted in the urine as intact about 50%. Other metabolites excreted by the renal route bind poorly to muscarinic receptors and are therefore not considered to contribute to the effects of hyoscine butylbromide.
2. Indications of Buscopan 20mg/ml
Buscopan 20mg/ml is indicated in the following cases
Gastrointestinal spasms: Gastrointestinal spasms, biliary colic,... Urogenital - genitourinary spasms: Renal colic, contractions uterine contractions,... Dysmenorrhea due to uterine muscle spasms. Reducing spasms before performing subclinical procedures such as: gastrointestinal endoscopy, X-ray film, ...
3. Contraindications of Buscopan 20mg/ml
Cases in which Buscopan should not be used:
Patients with hypersensitivity to hyoscine butylbromide or any other ingredient of the drug. There are diseases: paralytic ileus, intestinal obstruction, gastrointestinal narrowing. Patients with myasthenia gravis. Patient has untreated narrow-angle glaucoma. Prostate enlargement in a patient with urinary retention. Fast heart beat. Intramuscular injection should not be given to patients on anticoagulant therapy because intramuscular hematoma may occur. (The drug can be administered intravenously or subcutaneously) Notes when using Buscopan:
In cases of severe abdominal pain of unknown cause, not self-administering Buscopan will fade acute symptoms study of surgical diseases. Use with caution in patients prone to narrow-angle glaucoma; patients with a predisposition to gastrointestinal - urinary tract obstruction; Patients with tachycardia arrhythmias. Some animal studies have shown the harmful effects of Buscopan on the embryo, so it should not be used in pregnant women. Breastfeeding women should limit Buscopan injection because there is not enough evidence to prove the safety of the drug for the baby.
4. Dosage and usage of Buscopan
Usage:
The drug is prepared in the form of an injection solution; slow intravenous, intramuscular or subcutaneous injection. Dosage:
Adults and children > 12 years old: Inject 1 - 2 ampoules of Buscopan (20 - 40 mg) x 2 - 3 times/day. The maximum daily dose should not exceed 100 mg/day. Infants and children: Inject 0.3 - 0.6 mg/kg body weight x 2 - 3 times/day. The maximum daily dose should not exceed 1.5 mg/kg body weight/day.
5. Side effects of Buscopan
When using Buscopan, there may be some unwanted side effects as follows:
Anaphylaxis. Fast heart beat. Dry mouth feeling. Sweating disorders: increased or decreased secretion. Urinary retention or decreased urine output. Eye accommodation disorder, eye fatigue, pupil dilation, glaucoma. Decreased blood pressure, headache, dizziness, flushing. Above is information about the drug Buscopan 20 has what effect, dosage and note when using. To ensure safety for your health and maximize the effectiveness of your treatment, you need to take Buscopan exactly as directed by your doctor.
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