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Bucarvin belongs to the group of anesthetics, analgesia, has the effect of layer-by-layer anesthesia for surgery, epidural anesthesia for caesarean section, spinal anesthesia, postoperative pain relief, pain relief after labor. So, Bucarvin is specifically indicated in which cases?1. What is Bucarvin?
Bucarvin has the main active ingredient Bupivacaine hydrochloride 20mg and other excipients just enough. The drug is prepared for users in the form of an epidural injection solution, packaged in a box, each box of 5 ampoules x 4ml of solution.
2. Uses of Bucarvin
2.1 Uses - indications Bucarvin is used in the following cases:
Used for layering anesthesia during surgery, epidural anesthesia during surgery, pain relief after surgery, pain relief during labor. Has the effect of nerve plexus and nerve block for performing surgery. Helps to numb the spinal cord when performing urology surgery in the lower abdomen, lower limbs and caesarean section. 2.2 Contraindications Patients with hypersensitivity to local anesthetics, of the amide group. Absolutely do not use regional anesthesia by intravenous line or anesthesia around the cervix in obstetrics. Because there has been a case of cardiac arrest in the mother. Do not use for epidural and spinal anesthesia in patients with severe hypotension when in cardiogenic shock, due to blood loss, taking anticoagulants or with coagulation disorders.
3. How to use and dose Bucarvin
How to use: Bucarvin is prepared as an anesthetic injection solution, so it should be used by injection. However, users need to note the following:
Be very careful to avoid accidentally injecting into a vein, therefore, before injecting, it is imperative to have a test aspiration, if the syringe is visible. If there is blood, you must choose another site for injection. During epidural anesthesia, a test dose of 3 - 5 ml of epinephrine-containing bupivacaine should be injected, which will be detectable immediately upon vascular injection due to increased heart rate. At that time, it is necessary to stop the injection and try again at another location. After 5 minutes of injection, it is necessary to talk to the patient and check the heart rate, try again until the entire drug is injected at a slow rate of 20-25 mg/ minutes, if mild symptoms of toxicity are detected, the injection should be stopped immediately. Always have respiratory and circulatory equipment available when injecting to be able to provide first aid in time for unwanted symptoms. Dosage:
For penetrating anesthesia: use up to 150mg (60ml) for adults with 0.25% solution For peripheral nerve blockade: use a dose of 5ml of 0.25% solution or 5ml of solution 0.5%, maximum 150mg Used to block sympathetic nerves: use dose of 20 -500 ml of 0.25% solution, maximum 150mg Use in eye surgery, post-ocular anesthesia: use dose of 2 - 4ml solution 0.75% solution Used for lumbar epidural anesthesia: During surgery: use 10 - 20ml of 0.25% solution or 10 - 20ml of 0.5% solution when muscle relaxation is needed. Pain relief during labor: use dose 6-12ml 0.25% or 0.5% solution Use in lower extremity and pelvic surgery: 1ml dose Use in lower abdominal surgery: 1.6ml dose Use intraoperatively hysterectomy: use dose 1 - 1.4ml Note: The above dose is for reference only, patients should be consulted and determined by a doctor when using the drug.
In case of missed dose: the medicine is taken by a doctor so it is very unlikely that a dose will be missed. If unfortunately missed dose, the patient should remind immediately to be taken.
In case of overdose: There is no specific treatment for overdose of Bucarvin. In case of overdose, the user should stop taking the drug immediately and go to the hospital to treat the symptoms. In case of an emergency, go to the nearest medical facility or call 911.
4. Side effects of Bucarvin
When using the drug, the patient may experience unwanted symptoms such as:
Effects on the circulatory system: causing low blood pressure, slowing down the heart rate during spinal anesthesia. Central nervous system effects: loss of consciousness and convulsions in overdose, paresthesia, muscle weakness and bladder dysfunction. It can cause a stroke if overdosed or mistakenly injected into an artery that carries blood to the brain. Some other symptoms: agitation, restlessness, ringing in the ears, numbness of the tongue and lips, dizziness, lightheadedness, slurred speech, a feeling of tightness in the chest, local muscle tremors. These symptoms present an alarm of toxicity, requiring immediate discontinuation of the injection. Continued use of the drug leads to loss of consciousness, convulsions, and total respiratory depression.
5. Bucarvin drug interactions
Users need to be aware of the following interactions with Bucarvin:
Bucarvin with epinephrine should not be used with tricyclic antidepressants or MAO inhibitors: can cause severe and prolonged hypertension. long. When combined with active ingredients bupivacaine with vasoconstrictor drugs: cause severe, prolonged high blood pressure and cause cerebrovascular accident. When used in combination with phenothiazines and butyrophenone: reduces or reverses the effect of epinephrine. When used with class I antiarrhythmic drugs: increases the toxicity of bupivacaine. When bupivacaine is used in people who have been or are taking the drugs chloroform, halothane, trichlorethlen, cycloprpan: may cause severe arrhythmias.
6. Notes when using Bucarvin
When using the drug, users need to know the following information:
Be careful when using Bucarvin for liver disease, because the active substance Bupivacaine is metabolized in the liver. The drug can cause unwanted allergic reactions Absolutely do not use the drug with solutions containing preservatives for bone or epidural anesthesia: it will cause seizures due to severe systemic toxicity. central nervous system, which can cause cardiac arrest, especially when mistakenly injected into a blood vessel. Bucarvin is potentially more cardiotoxic than other local anesthetics, so it should be used with great caution in patients with cardiovascular dysfunction. When the drug is used in pregnant women, it is necessary to reduce the concentration and reduce the dose because of the increased susceptibility to bupivacaine during pregnancy. For those who are breast-feeding, if taking the drug at a therapeutic level, the amount of medicine will not affect the infant. Caution should be exercised when administering the drug to people who are driving a vehicle, boat or operating similar machinery. Hopefully, the information shared about Bucarvin such as effects - contraindications, usage and some other necessary notes will help users better understand the drug and get the best effect in the process. use.
