Uses of Bilclamos 625mg

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1. What is Bilclamos 625mg?

What is Bilclamos 625mg? Bilclamos medicine 625mg has the active ingredient Amoxicillin in the form of Amoxicillin trihydrate with the content of 500mg and clavulanic acid in the form of Potassium clavulanate with the content of 125mg. The drug has anti-parasitic, anti-infective, anti-viral and anti-fungal effects.
Bilclamos 625mg is made in the form of film-coated tablets, suitable for direct oral use. Packing is a box of 2 blisters, each blister contains 5 pills.
1.1. Pharmacodynamics of the active ingredient Bilclamos 625mg is an antibiotic with a broad spectrum of antibacterial activity. The combination of Amoxicillin with clavulanic acid prevents Amoxicillin from being destroyed by beta-lactamases, and at the same time effectively extends the antibacterial spectrum of the antibiotic Amoxicillin to many bacteria that are already resistant to Amoxicillin and other penicillins. and Cephalosporins.
1.2. Pharmacokinetics of the active substance The two main active ingredients, Amoxicillin and Clavulanic Acid, are readily absorbed orally. The concentration of these 2 substances in the serum reaches the maximum after 1 to 2 hours of taking the drug. The average oral bioavailability of Amoxicillin is 90% and that of clavulanic acid is 75%. The biological half-life of Amoxicillin in serum is about 1 to 2 hours and that of clavulanic acid is about 1 hour. 55–70% of Amoxicillin and 30–40% of clavulanic acid are excreted unchanged in the urine.

2. What disease does Bilclamos 625mg treat?

Bilclamos medicine 625mg is effective for short-term treatment of the following infections:
Treatment of upper respiratory tract infections: Tonsillitis, sinusitis or otitis media that have been treated with common antibiotics but no relief. Treatment of lower respiratory tract infections caused by beta-lactamase producing strains of H. influenzae and Branhamella catarrhalis: Acute and chronic bronchitis, pneumonia and bronchitis. Treatment of serious infections of the urogenital tract caused by beta-lactamase-producing strains of E. coli, Klebsiella and Enterobacter: Cystitis, urethritis, pyelonephritis or female genital tract infections. Treatment of skin and soft tissue infections: boils, abscesses or wound infections. Treatment of infections with the musculoskeletal system: Osteomyelitis. Treatment of dental infections: Abscesses in the sockets. Treatment of other infections: obstetric and gynecological infections, intra-abdominal infections.

3. Usage and dosage of Bilclamos 625mg

Dosage of the drug Bilclamos 625mg is calculated according to the content of amoxicillin in the drug.
Dosage for adults and children ≥ 12 years old:
Treatment of mild and moderate infections: use 1 tablet equivalent to 500mg amoxicillin every 12 hours. Treatment of severe infections: use 1 tablet equivalent to 500 mg Amoxicillin every 8 hours. Dosage for children 6 years old and weighing < 25 kg should be treated as a suspension or as a sachet. Patients should take the drug at the beginning of a meal to minimize drug intolerance in the gastrointestinal tract. The duration of treatment with Bilclamos 625mg should not exceed 14 days without re-examination.
In case of overdose: When overdosing, Bilclamos 625mg drug rarely causes complications because it is well tolerated even at high doses. However, the acute reactions that occur depend on the hypersensitivity of the particular person. The risk is definitely increased potassium in the blood when used in very high doses because the active ingredient clavulanic acid is taken as the potassium salt. The treating doctor may prescribe hemodialysis to remove the drug from the circulation.

4. Undesirable effects of the drug Bilclamos 625mg

In the process of using Bilclamos 625mg, there may be some unwanted effects, specifically as follows:
Common unwanted effects: Diarrhea, rash, itching on the skin. Uncommon side effects: Increased eosinophil count, nausea, vomiting, hepatitis and cholestatic jaundice, increased transaminases. Rare adverse reactions: Anaphylaxis, Quincke's edema, mild thrombocytopenia, decreased white blood cell count, hemolytic anemia, pseudomembranous colitis, Stevens-Johnson syndrome, erythema multiforme forms, atopic dermatitis, toxic epidermal necrolysis, and interstitial nephritis. Patients need to proactively notify the treating doctor of any unwanted effects that you experience during the use of the drug.

5. Drug interactions of Bilclamos 625mg

Interactions of Bilclamos 625mg may occur as follows:
Bilclamos 625mg may cause prolongation of bleeding time and clotting time. Therefore, care should be taken in patients being treated with anticoagulants. Bilclamos 625mg can reduce the effectiveness of oral contraceptives, so it is necessary to inform the patient in advance. Probenecid prolongs the elimination time of active ingredient Amoxicillin but does not affect the elimination of clavulanic acid.

6. Some notes when using Bilclamos 625mg

6.1. Contraindications of the drug Bilclamos 625mg People with sensitive or hypersensitivity to Beta - lactam group (specifically, Penicillin, Cephalosporin drugs). People with a history of jaundice or hepatobiliary disorders caused by taking Amoxicillin, Clavulanate or Penicillins. 6.2. Notes and precautions of the drug Bilclamos 625mg For patients with manifestations of liver dysfunction, kidney failure. For pregnant women: Avoid using Bilclamos 625mg for pregnant women, especially in the first 3 months, unless it is necessary as prescribed by the treating doctor. During breastfeeding, Bilclamos 625mg can be used, because it is not harmful to a nursing infant, unless there is a risk of sensitization due to the presence of very small amounts of the drug in milk. Above is all information about Bilclamos 625mg drug, patients need to carefully read the instructions for use, consult a doctor / pharmacist before using. Absolutely do not arbitrarily buy Bilclamos 625mg at home, because there may be unwanted side effects.
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