Uses of Bexis 7.5

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1. Uses of the drug Bexis 7.5

Bexis 7.5 drug has the main ingredient Meloxicam 7.5mg. In addition, on the market, there is also the form of Bexis 15 with the ingredient Meloxicam 15mg. This article mainly focuses on the Bexis 7.5 content form. Meloxicam is a non-steroidal anti-inflammatory drug (NSAID) belonging to the oxicam family with anti-inflammatory, analgesic and antipyretic properties. Meloxicam has strong anti-inflammatory properties for all types of inflammation with the mechanism of: Inhibiting the biosynthesis of prostaglandins - mediators of inflammation.
Indications for use of Bexis 7.5: Long-term symptomatic treatment of chronic inflammatory pain in:
Osteoarthritis: Osteoarthritis or joint damage; Rheumatoid arthritis ; Ankylosing spondylitis . Contraindications to the use of Bexis 7.5:
Patients with a history of hypersensitivity to Meloxicam components or other excipients of the drug; Persons with cross-sensitivity to Aspirin and other NSAIDs; Patients with a history of asthma, angioedema, nasal polyps or urticaria after taking aspirin or other NSAIDs; Patients with advanced gastric - duodenal ulcer; Patients with severe liver failure; Patients with severe renal failure but not on dialysis; Pregnant women and lactating mothers; Children under 15 years old.

2. Usage and dosage of Bexis 7.5

Usage: Orally.
Dosage:
Rheumatoid arthritis, ankylosing spondylitis: Take 2 tablets/day. Depending on the patient's response to treatment, the dose can be reduced to 1 tablet/day; Osteoarthritis: Take 1 tablet/day. If necessary, the dose can be increased to 2 tablets/day; Patients at high risk of side effects: Initial treatment with a dose of 1 tablet/day; Patients with severe renal failure requiring hemodialysis: Do not exceed 1 tablet/day; Children: The dose has not been determined, so the drug is only used in adults; When using combination pills, injection: The total dose should not exceed 2 tablets/day. Overdose: In case of overdose of Bexis 7.5 and having emergency symptoms, the patient should call 911 immediately for guidance and help.
Missed dose: If you miss a dose of Bexis 7.5, you can take it as soon as you remember. If the time to remember is near to the next dose, the patient should skip the missed dose and take the next dose as originally planned.

3. Side effects of the drug Bexis 7.5

Some side effects patients may experience when taking Bexis 7.5 include:
Digestive: Diarrhea, abdominal pain, flatulence, indigestion, vomiting, ... and transient abnormalities due to functional changes liver function; Hematology: Blood count disorders (disorders of white blood cells, thrombocytopenia), anemia. If Bexis 7.5 is used concurrently with drugs that are toxic to bone marrow, especially methotrexate, it can cause blood cell depletion; Skin: Skin itching, rash, urticaria, photosensitivity, stomatitis; Respiratory system: Rarely, the onset of acute asthma attacks; Central nervous system: Drowsiness, tinnitus, dizziness, headache; Cardiovascular system: Edema, hypertension, palpitations, flushing; Urinary system: Increased blood urea, increased blood creatinine; Hypersensitivity reactions: Anaphylactic reactions and mucosal edema. Patients should immediately notify the doctor about the side effects when using Bexis 7.5 for timely intervention.

4. Precautions when using Bexis 7.5

Some notes patients need to remember before and while taking Bexis 7.5:
Meloxicam (main ingredient of Bexis 7.5) should not be used as a substitute for corticosteroids or used to treat corticosteroids deficiency. Abruptly stopping corticosteroids can make the condition worse. If a decision is made to discontinue corticosteroid therapy, a gradual dose reduction should be made in patients on prolonged corticosteroid therapy; When using Bexis 7.5, patients may experience serious liver reactions including jaundice, acute hepatitis, liver necrosis and liver failure. These symptoms are very rare. Therefore, patients with signs of liver dysfunction or those with abnormal liver function tests, whose symptoms are associated with progression of liver disease or systemic symptoms (rash, decreased eosinophils,...) should stop treatment with Bexis 7.5; Bexis 7.5 should be used with caution in dehydrated patients. It is recommended to use rehydration before using the drug; The drug should be used with caution in patients with a history of kidney disease. Some metabolites of Meloxicam are excreted by the kidneys, so close monitoring is required in patients with severe renal impairment; Some patients experience fluid retention and edema when using Meloxicam. Therefore, caution should be exercised when administering the drug in patients with fluid retention, heart failure and hypertension; If the patient has side effects such as dizziness, drowsiness when taking the drug, it is necessary to be careful when driving or operating machinery; Pregnant women should consider and consult a doctor before taking Bexis 7.5; Nursing mothers should consult a doctor before using Bexis 7.5.

5. Bexis drug interactions 7.5

Some drug interactions of Bexis 7.5 include:
Concomitant use of Bexis 7.5 with other NSAIDs increases the risk of gastrointestinal bleeding due to synergistic effects; Concomitant use of Bexis 7.5 with anticoagulants, thrombolytic drugs such as ticlopidine, heparin will increase the risk of bleeding; Concomitant use of Bexis 7.5 with Lithium will increase the concentration of Lithium in the blood plasma; Concomitant use of Bexis 7.5 with Methotrexate will increase toxicity on the hematopoietic system; Bexis 7.5 may reduce the effectiveness of intrauterine contraceptives; Concomitant use of Bexis 7.5 with diuretics increases the risk of acute renal failure in dehydrated patients; Concomitant use of Bexis 7.5 with antihypertensive drugs such as beta-blockers, diuretics, ACE inhibitors, vasodilators,... will reduce the antihypertensive effect; Concomitant use of Bexis 7.5 with Cholestyramine will increase the elimination of Meloxicam (due to the phenomenon of binding in the gastrointestinal tract); Concomitant use of Bexis 7.5 with Cyclosporin will increase the nephrotoxicity of Cyclosporin. When using Bexis 7.5, patients should strictly follow the doctor's instructions. In addition, patients also need to inform the doctor about the medicines/medicines that protect their health or the diseases they are suffering from. This ensures effective treatment and reduces the risk of unpredictable events.
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