Uses of Betahistine 24

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1. Uses of Betahistine 24

1.1. Indications Betahistine 24 contains the active ingredient Betahistin 24mg is indicated in the treatment of the following symptoms:
Dizziness with facial flowers, nausea; Hearing loss, difficulty hearing; Tinnitus (sounds heard inside the ear do not correspond to those outside); Symptomatic treatment of vestibular vertigo (dizziness, nausea especially when changing positions). 1.2. Pharmacodynamics Active ingredient Betahistine has a synergistic effect on histamine H1, no activity on histamine H2 and an antagonist on histamine H3. The drug works to relax the pre-capillary sphincter, increasing blood flow in the ear. In addition, Betahistin also helps to control the permeability of the capillaries in the ear, thereby helping to eliminate the accumulation of endolymphatic fluid in the inner ear. Betahistine also has the effect of improving cerebral blood circulation, increasing blood flow in the internal carotid artery. Therefore, in clinical practice, Betahistin is effective in reducing dizziness and lightheadedness.
1.3. Pharmacokinetics After oral administration, Betahistine is rapidly and completely absorbed from the gastrointestinal tract. The drug is mainly excreted in the urine as a 2-pyridylacetic acid metabolite, the time of metabolism and elimination occurs within 24 hours after oral administration. Almost no intact Betahistine was found excreted in the urine.

2. Dosage of Betahistine 24

Dosage of Betahistine 24mg depends on age and medical condition, specifically as follows:
Adults: The starting dose is 8-16mg x 3 times/day, the maintenance dose is from 24 - 48mg/day . Note that the daily dose should not exceed 48mg. Adolescents and children: Betahistin 24 is not recommended to be used in the treatment of children under 18 years of age because there are no adequate studies on the efficacy and safety of the drug in these subjects; Patients with liver failure, kidney failure: There have not been enough studies on the safety of the drug, so it is recommended not to use Betahistin in patients with liver or kidney failure; Elderly: Use caution when treating with Betahistine.

3. Side effects of Betahistine 24

Some side effects may be encountered when using Betahistine 24mg as follows:
Common: Headache, indigestion, nausea; Uncommon: Insomnia, hypersensitivity reactions (urticaria, angioedema, pruritus and rash), palpitations, gastrointestinal irritation (stomach pain, vomiting, flatulence, abdominal distension). In case of experiencing unwanted effects, the patient should stop using Betahistine and notify the treating doctor for timely treatment.

4. Notes when using Betahistine 24

4.1. Contraindications Contraindicated to use Betahistin 24 in the following cases:
Patients are sensitive to Betahistin or to any ingredient of the drug; People with stomach - duodenal ulcers; Patients with adrenal myeloma. 4.2. Precautions for use Use caution when using Betahistine 24mg in patients with a history of gastric ulcer. Clinically, there have been many cases of bronchial asthma intolerant to Betahistine. Therefore, caution should be exercised when using Betahistine in these subjects. Use caution when using the drug in patients with urticaria, allergic rhinitis, skin rash because the drug aggravates these conditions. Betahistine should be used with caution in patients with severe hypotension. Do not use the drug in patients with Lapp lactase deficiency, hereditary lactose intolerance or glucose-galactose malabsorption. Pregnant women: There are no studies demonstrating the safety of Betahistine in the treatment of pregnant women. Therefore, it is not recommended to use the drug in the treatment of pregnant women. Lactation: There are no studies demonstrating the ability of Betahistin to be excreted in human milk. Therefore, the use of Betahistine in lactating women should be prescribed by the treating physician, based on the balance of benefits and risks. Drivers and machine operators: Betahistin 24 is indicated in the treatment of symptoms of tinnitus, dizziness, hearing loss... these are symptoms that greatly affect the ability to drive and operate machines. hook. Although studies have demonstrated that Betahistine has no effect on the ability to drive, patients should exercise caution when driving or operating machinery to ensure safety and effectiveness of treatment.

5. Drug interactions Betahistine 24

Betahistine 24 may interact with the following drugs:
Antihistamines; Ethanol; Medicines containing pyrimethamine and dapsone; Selegiline drug; Salbutamol.

6. Dealing with drug overdose and forgetting a dose of Betahistine 24

Overdose: Using an overdose of Betahistine can cause symptoms of drowsiness, nausea, abdominal pain, convulsions, heart or lung complications... In this case, the patient should be taken to the hospital. medical facility as soon as possible for timely treatment. Missing a dose: In case of forgetting a dose, the patient should take it as soon as he remembers. If the dose is close to the next dose, the patient should skip the missed dose and continue taking the medicine as scheduled, never taking a double dose. Betahistin 24 contains the active ingredient Betahistin, which is indicated in the treatment of symptoms of tinnitus, dizziness, hearing loss... To ensure effective treatment and avoid unwanted side effects, patients need to follow it. Follow the instructions of your doctor or pharmacist.
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