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Beclogen cream contains the main active ingredients Betamethasone, Clotrimazole and Gentamycin sulfate. The drug is used in the treatment of people with corticosteroid-responsive dermatitis when complicating secondary infections, atopic skin diseases and fungal skin diseases.
1. What is Beclogen cream?
What is Beclogen? The main ingredients of Beclogen Cream include:
5 mg of active ingredient Betamethasone, in the form of Betamethasone dipropionate; 100 mg of the active ingredient Clotrimazole; 10 mg of the antibiotic Gentamicin in the form of Gentamicin sulfate; Excipients are just enough for each tube of topical medication. Beclogen Cream is prepared in the form of a topical cream.
Packing is a box of Beclogen cream with 1 tube weighing 10 grams.
1.1. Pharmacodynamics of active ingredient Betamethasone belongs to the group of Glucocorticoid drugs, effective in reducing inflammation in a number of diseases such as rheumatoid arthritis, lupus erythematosus, dermatitis, psoriasis or asthma.
Active ingredient Clotrimazole is an active ingredient in the group of antifungal drugs, often used in the treatment of fungal skin infections, oral thrush, tinea versicolor. The mechanism of action of the active ingredient Clotrimazole is that Clotrimazol changes the permeability of the cell membrane, thereby losing the ability to select cells and kill bacteria. Clotrimazol has a broad spectrum of action, killing both fungi and bacteria. Gentamicin belongs to the group of antibiotics that kill bacteria. Gentamicin has the ability to inhibit bacterial protein synthesis, thereby killing bacteria. Gentamicin is active against both gram-negative and gram-positive bacteria. Some specific gram-negative bacteria such as Pseudomonas, Proteus, Enterobacter aerogenes; Gram-positive bacteria such as Staphylococcus.
1.2. Pharmacokinetics of the active substance Clotrimazol is partially absorbed through the skin but poorly absorbed systemically. Clotrimazole is metabolized mainly by the liver to inactive metabolites. Clotrimazole is eliminated mainly through urine and feces.
Active ingredient Gentamicin has good absorption through the skin and diffuses mainly into the extracellular fluid, not being able to diffuse across the blood-brain barrier. Part of the active ingredient Gentamicin is found in breast milk and has the ability to cross the placental barrier. The half-life of the active substance is about 2 to 3 hours on average.
2. What disease does Beclogen Cream treat?
Beclogen Cream is indicated for use in a number of cases, specifically as follows:
Patients who are experiencing allergic skin conditions such as atopic dermatitis, allergic to sunlight, psoriasis psoriasis, rashes, skin rashes, eczema, contact dermatitis. People with hand and foot fungus, scalp fungus, thigh skin fungus.
3. Usage and dosage of Beclogen Cream
3.1. Dosage of Beclogen Cream A day, apply Beclogen Cream from 1 to 2 times on the skin to be treated in the morning and at night before going to bed. The duration of treatment lasts at least from 2 to 4 times. The dose can be adjusted depending on the severity of the condition or the location of the disease. The patient should follow the instructions given by the treating physician. Using Beclogen Cream after 3 to 4 weeks, if the condition does not improve, you should stop using it and find a more suitable treatment. 3.2. How to use Beclogen Cream Beclogen Cream is made in the form of a cream, suitable for external use. For optimal absorption of Beclogen Cream, you should wash the area to be treated with normal water or physiological saline, and gently pat dry with a cotton towel. Use a sufficient amount of Beclogen Cream to evenly apply to the area to be treated, combine with gentle relaxation massage for better drug absorption, and let the cream dry naturally. Limit contact with water after applying Beclogen Cream. Use Beclogen Cream in a continuous and regular time throughout the treatment course to achieve optimal treatment effects. 3.3. In case of overdose: Overdosing on Beclogen Cream leads to atrophy of the skin, a decrease in the amount of collagen in the skin. In cases where corticosteroids are absorbed in large amounts into the body, they can cause adrenal suppression. Patients should discontinue the drug and treat appropriately symptomatically. In case of overdose: Skip the missed dose and use the next normal dose. You need to be careful not to use a double dose to make up for the missed dose. Besides, you should also note that, do not forget the treatment dose more than 2 times in 1 course of treatment.
4. Undesirable effects of the drug Beclogen cream
Besides the effective uses that Beclogen Cream brings, this drug also causes some unwanted effects on users. These side effects are usually less frequent or less severe, do not affect the user's health and usually disappear after stopping the use of the drug.
According to statistical research, some unwanted effects may occur such as: itching, edema, burning, erythema multiforme, tiny blisters, urticaria, skin irritation, superinfection . In case the symptoms become severe, or the users of the drug detect any abnormality, they should notify the treating doctor as soon as possible or go to the medical facility as soon as possible. to be remedied in a timely manner.
5. Beclogen Cream drug interactions
During the use of Beclogen Cream, it may reduce the activity of Gentamicin antibiotics: Ca, Sulfafurazol, Lieparin, Sulfacetamide, Mg, Acetylcysteine, Chloramphenicol, Actinomycin, Doxorubicin, Clindamycin.
6. Some notes when using Beclogen cream
6.1. Contraindications of Beclogen Cream The use of Beclogen Cream is contraindicated in subjects with a history of allergy to any of the ingredients in the drug. Do not use Beclogen Cream for people who are sensitive to Aminoglycoside active ingredients. The use of Beclogen Cream is contraindicated for those who have skin tuberculosis or skin lesions with bacterial infection, shingles, smallpox, syphilis or skin cancer. Beclogen Cream is not allowed to be applied to the skin with open wounds. 6.2. Notes when using Beclogen Cream Some points to note during the use of Beclogen Cream are as follows:
Be careful when using Beclogen Cream with other drugs containing corticosteroids. Avoid getting Beclogen Cream on the eyes and sensitive skin and mucous membranes. In case the cream gets into the eyes, rinse immediately with water. Do not use Beclogen Cream for more than 4 weeks. After applying Beclogen Cream, do not bandage or apply the medicine on too large of the skin. Use Beclogen Cream normally while driving or operating heavy machinery. Store medicines away from play areas with small children. Store the medicine in a cool, dry place with an average temperature of 25 to 27 degrees Celsius. Avoid storing the medicine in areas or places exposed to direct sunlight. Avoid storing the medicine in humid and unsanitary places. You should not use products that have changed in quality, namely discolored, watery. Such products are at risk of being damaged or expired. Check the expiration date carefully before using this medicine. Above is all information about Beclogen Cream, patients need to carefully read the instructions for use, consult a doctor / pharmacist before use. Absolutely do not arbitrarily buy Beclogen Cream for home treatment, because there may be unwanted side effects.
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