This is an automatically translated article.
Drug Atroact-10 is used in treatment to reduce Total Cholesterol, Triglyceride, LDL Cholesterol along with increasing the concentration of HDL (good cholesterol). The active ingredient Atroact-10 is Atorvastatin. The following article shares about the use and notes when using Atroact-10.
1. What is Atroact-10?
Atroact-10 belongs to the group of cardiovascular drugs, is made in the form of film-coated tablets packed in boxes of 3 blisters x 10 tablets. '
Atroact-10 medicine contains the main ingredient is Atorvastatin (in the form of Atorvastatin calcium) 10mg and other excipients just enough for 1 tablet such as: Corn starch, microcrystalline cellulose, lactose, povidone, magnesium stearate, sodium methyl paraben , sodium propyl paraben, purified talcum powder, sodium glycolate starch paste, colloidal anhydrous silica, corn starch (dry), hypromellose , titanium dioxide, polyethylene glycol 6000, color: ponceau 4R.
2. What does Atroact 10 do?
Atroact-10 is used in the following cases:
Atroact-10 is used to support diet by reducing Total Cholesterol, Triglyceride, LDL Cholesterol, along with increasing the concentration. HDL (good cholesterol) for patients even in those with a family history of the disease. Atroact-10 is used in cases of disorders of blood Betalipoprotein levels such as type 3 hyperlipidemia. Atroact-10 is used in combination with other measures to reduce blood lipids to treat patients.
3. Dosage - How to take Atroact-10
Atroact-10 can be taken at any time of the day, regardless of the meal and drink it with a sufficient amount of water. Atroact-10 is used orally without other sugars.
Reference dosage of Atroact-10 is as follows:
Hypercholesterolemia (Non-familial or heterozygous) and mixed dyslipidemia: the recommended starting dose is 10-20mg Atorvastatin , 1 time/day. Patients who need a significant reduction in LDL cholesterol (more than 45%) can start with 40 mg of Atorvastatin once daily. The therapeutic dose range of the drug is 10-80mg Atorvastatin once daily. After starting treatment or after increasing the dose of Atroact-10, the patient should assess the blood lipid index within 2 - 4 weeks and to adjust the dose accordingly. Homozygous familial hypercholesterolemia: 10-80mg Atorvastatin/day. Should be combined with other lipid-lowering measures. Combination treatment: Atroact-10 can be used in combination with resin to increase the effectiveness of treatment. Dosage in patients with renal failure : No dose adjustment of Atroact-10 is required .
4. Contraindications to taking Atroact-10
Atroact-10 should not be used in the following cases:
Patients with hypersensitivity to Atorvastatin, HMG-CoA reductase inhibitors or any ingredient in the formulation. Patients with progressive liver disease or unexplained persistent elevations in serum transaminases. Pregnant women Breastfeeding mothers.
5. Atroact-10 drug interactions
Here are some drugs when combined with Atroact-10 that can cause drug interactions such as:
Anticoagulants, indandione combined with Atroact-10 will increase bleeding time or prothrombin time . Prothrombin time should be monitored in patients receiving concomitant anticoagulants. Erythromycin, Cyclosporine, Gemfibrozil, immunosuppressants, Niacin when taken with Atroact-10 cause an increased risk of myopathy. Digoxin used in combination with Atroact-10 causes a slight increase in digoxin serum concentrations This is not a complete list of Atroact-10 drug interactions. To ensure the safety of using Atroact-10, the patient should inform the doctor about any other medical conditions that he or she is having and the lines of drugs and medicines being used. To avoid unwanted drug interactions Atroact-10 occurs.
6. What side effects does Atroact-10 cause?
Atroact-10 is well tolerated. Adverse effects are usually mild and transient. Less than 2% of patients in clinical trials discontinued treatment due to side effects of atorvastatin.
The most common side effects > 1% of Atroact-10 treatment in patients enrolled in controlled clinical studies were:
Psychiatric disorders: Insomnia, difficulty falling asleep Disorders Nervous system: Headache, headache. Gastrointestinal disorders: Nausea, vomiting, abdominal pain, diarrhea, constipation, digestive disorders, abdominal bloating. Bone and muscle disorders, connective soft tissues: Myalgia. Disorders: asthenia, cognitive decline, confusion, memory loss,... hyperglycemia, increased HbAlc. Patients should inform their doctor and pharmacist of any unwanted effects encountered when using Atroact-10.
7. Pay attention to precautions when using Atroact-10 treatment
Before treatment with Atroact-10, it is necessary to conduct periodic quantification, with an interval of not less than 4 weeks and pay attention to excluding the causes of secondary dyslipidemia - it is necessary to measure the lipid indices.
During treatment with Atroact-10 with HMG-CoA reductase inhibitors, if creatine kinase is increased, serum liver enzymes are increased 3 times the normal limit or there is inflammation of the muscles, the dose should be reduced or stop treatment.
Use Atroact-10 with caution in patients with liver dysfunction, patients who drink a lot of alcohol.
Patients need to have a reasonable diet before treatment with Atroact-10, should maintain this diet during treatment with Atroact-10.
The use of Atroact-10 in the treatment of pathologies should be done by a doctor or pharmacist. Patients do not arbitrarily buy drugs to use because this can seriously affect their health.
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