This is an automatically translated article.
Fexofenadine is the active ingredient commonly used in the treatment of common allergies. One of the commonly used commercial products is A.T Fexofenadine 30ml bottle, 30mg/5ml content.
1. What is A.T Fexofenadine?
A.T Fexofenadine is prepared in the form of an oral suspension, each tube has a volume of 30ml with the main active ingredient being Fexofenadine hydrochloride 30mg/5ml. It means that in 1 ampoule there is a drug content of Fexofenadine 180mg. This is a product of An Thien Pharmaceutical Company.
2. Indications of the drug A.T Fexofenadine
Fexofenadine Hydrochloride is a salt form of the active ingredient Fexofenadine, a carboxylated derivative of Terfenadine. This is a selective long-acting H1-receptor antagonist and belongs to the second generation of H1-antagonists. Fexofenadine, when taken into the body, will compete for binding with histamine at peripheral H1 receptors, present in the gastrointestinal tract, blood vessels and bronchial smooth muscle. This effect inhibits the binding of histamine to peripheral H1 receptors, thereby blocking the activity of this binding and preventing Histamine-mediated allergic reactions.
Therefore, the drug A.T Fexofenadine (30ml bottle) is indicated for use in the following cases:
Treatment of allergy symptoms caused by many causes, especially allergies caused by weather changes; Treat some conditions such as itching, rash ...
3. Instructions for using the drug A.T Fexofenadine
3.1. Dosage of the drug Fexofenadine 180mg Patients with seasonal allergic rhinitis or chronic urticaria:
Adults and children over 12 years old: Take 20ml of Fexofenadine A.T (equivalent to 120mg) in 2 divided doses or 30ml. equivalent to 180mg) 1 time per day; Children from 6 to 12 years old: take 10ml of Fexofenadine A.T drug per day (equivalent to 60mg Fexofenadine), divided into 2 times. Dosage of A.T Fexofenadine for neonates with renal failure:
Children from 2 to 11 years old: The starting dose is 5ml (equivalent to 30mg) per day; Children from 6 months to under 2 years old: start taking 2.5ml of Fexofenadine A.T (equivalent to 15mg) per day. Dosage of Fexofenadine A.T should be adjusted appropriately for special populations, including patients with impaired renal function and the elderly.
3.2. How to use A.T Fexofenadine Fexofenadine 180mg drug is prepared in the form of an oral suspension, so patients only use the drug orally. Patients need to take the drug directly, not mixed with other solutions. At the same time, absolutely do not arbitrarily use A.T Fexofenadine by other routes not mentioned in the instruction sheet.
4. Contraindications of the drug A.T Fexofenadine
Fexofenadine A.T is absolutely not used for people with hypersensitivity or a history of allergy to any of the ingredients in this product.
In addition, Fexofenadine 180mg is also contraindicated in patients with impaired liver or kidney function.
5. Fexofenadine A.T side effects
Some unwanted side effects that may appear when using Fexofenadine A.T drug include:
Digestive dysfunction such as nausea, vomiting, abdominal pain, indigestion, sometimes constipation or diarrhea run; Increased liver enzymes, itchy rash or skin rash; Some patients after taking Fexofenadine A.T have headaches and insomnia ; Some less common side effects such as dizziness, dizziness, lightheadedness, mental tension, agitation; Hyperbilirubinemia; Increased risk of genital candidiasis or vaginitis; Increased or decreased blood pressure; Heart rhythm disturbances; Muscle weakness, muscle pain; Achilles tendonitis; Rarely psychosis or convulsions, especially severe anaphylaxis or Quincke's edema. In addition, patients may experience some other side effects during treatment with Fexofenadine A.T. Therefore, if any abnormal symptoms appear, the patient should stop taking Fexofenadine 180mg and notify the treating doctor or directly to the medical facility for timely intervention.
6. Pharmacological interactions of the brand name drug Fexofenadine
The active ingredient Fexofenadine in the drug A.T. Fexofenadine may interact with a number of substances after simultaneous use:
The antifungal drug Ketoconazole and the antibiotic Erythromycin can increase the concentration of Fexofenadine in the blood plasma; The drug A.T Fexofenadine reduces absorption when combined with gastric antacids containing aluminum or magnesium; The rate and extent of absorption of Fexofenadine A.T decreased when taken with orange, grapefruit, and apple juice.
7. Some notes when using Fexofenadine A.T
The most important thing is that the patient should use the drug A.T Fexofenadine according to the instructions and instructions of the doctor. If you have any questions, please discuss with your doctor, especially unwanted effects.
Need to pay special attention and monitor the use of Fexofenadine A.T for the elderly or with impaired liver and kidney function.
The safety and efficacy of Fexofenadine A.T. in pediatric patients under 6 years of age have not been studied.
Animal studies have reported some harmful effects on the fetus (such as teratogenicity, fetal death or other negative effects) of Fexofenadine A.T, however, there are no controlled studies in humans. Therefore, pregnant and lactating women must minimize the use of Fexofenadine A.T. Fexofenadine, at the same time, must be prescribed by a doctor and must ensure that the benefits outweigh the risks. benefit mother and fetus.
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