Uses of Aspilets ec 80mg

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1. What is Apilet?

Aspilets ec 80mg is a prescription drug, belonging to the category of anticoagulant, antiplatelet and fibrinolytic drugs. Aspilet has the active ingredient acetylsalicylic acid.
Dosage form: enteric-coated film-coated tablets, each containing 80mg of acetylsalicylic acid and excipients just enough.
Packing form: blister of 10 tablets, box with 1 blister, 3 blisters or 10 blisters.

2. Mechanism of action of the drug Aspilet ec

Pharmacodynamics: Acetylsalicylic acid is a derivative of salicylic acid, which has analgesic, antipyretic, and anti-inflammatory effects. It also has antiplatelet properties. Acetylsalicylic acid is rapidly absorbed and has high bioavailability. In adults, different doses of acetylsalicylic acid have different therapeutic effects. For example, with a plasma concentration of 30-60mg/L, acetylsalicylic acid has antipyretic and analgesic effects, while plasma concentrations of 40-100mg/L have anti-inflammatory effects. Acetylsalicylic acid exerts its anticoagulant effect through indirect inhibition of platelets by acetylation of cyclooxygenase in platelets, thereby preventing thromboxane synthesis by platelets. This inhibitory effect persists for the lifetime of platelets, which is about 8-9 days. Thus, inhibition of thromboxane synthesis is cumulative during subsequent administrations. Pharmacokinetics: Aspilet ec is absorbed from the intestine, then distributed in the liver and blood and is hydrolyzed to salicylic acid. The half-life of acetylsalicylic acid is 20 to 30 minutes at a dose of 500 mg, and that of salicylic acid is 2.5 to 3 hours. The half-life is increased with higher doses. Aspilet ec is eliminated mainly by the kidneys in the form of free and conjugated salicylates.

3. Indications and contraindications of the drug Aspilet ec

Aspilet 80mg drug is indicated in the following cases:
Prevention of recurrence in subjects with a history of cardiovascular diseases such as coronary artery disease, stroke, myocardial infarction, angina attack, surgery. Coronary artery, ... Prophylaxis of thrombosis in subjects at high risk of atherosclerosis, including factors: high LDL-cholesterol, men over 40 years old, premenopausal women, high blood pressure, diabetes diabetes, family history of coronary heart disease, tobacco use. Absolutely do not use Aspilet 80mg drug for the following subjects:
People who are allergic to any ingredient of Aspilet ec Have asthma and other diseases in the nose such as rhinitis, nasal polyps History of gastrointestinal ulcers (causes gastrointestinal bleeding because of gastric mucosal irritation) Liver failure, kidney failure, cirrhosis Heart failure Hemophilia and thrombocytopenia Note:
For alcoholic patients: consumption of more than 3 glasses of alcohol per day should Consult your doctor, as alcoholism is associated with an increased risk of bleeding when taking the drug. For patients with coagulopathy: avoid taking Aspilet ec, because this drug can prolong bleeding time by inhibiting the coagulation function of platelets.

4. Dosage and how to use Aspilets ec 80mg

Adults with stroke/transient ischemic attack: start with 50 – 325 mg once daily and should be continued for life. Adults with acute myocardial infarction: orally 160mg/day x 30 days after myocardial infarction. Then, another treatment may be considered to prevent recurrence. Prophylaxis of recurrent myocardial infarction, angina, and cardiovascular disease in patients with diabetes: initiate with 75–325 mg once daily and should be maintained for life. Adults undergoing coronary bypass surgery: 325mg/day after surgery and maintained for 1 year. Adults undergoing coronary angioplasty: Oral dose of 325mg, taken 2 hours after the procedure and should be maintained for life with 160-325mg/day. Adults undergoing carotidectomy: 80 mg orally before surgery and 650 mg orally twice a day and should be maintained for life. Prevention of gestational hypertension, preeclampsia, ..: 80mg/day from week 13 to 26 of pregnancy. Treatment of missed dose/overdose:
Missed dose: If you miss a dose, take another dose of Aspilet ec as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take your next dose as scheduled. Never take 2 doses next time to make up for the missed dose. Overdose: some symptoms may occur such as tinnitus, deafness, rapid, deep breathing, dilated blood vessels, sweating, .. Please stop the drug and immediately go to the nearest medical facility for timely treatment. Always remember to bring all the medicines you are taking, including prescription and over-the-counter medicines, dietary supplements, vitamins, herbs, etc. Currently there is no specific antidote, Treat with gastric lavage and possibly alkalinize the urine to increase elimination of Aspilet ec.

5. Side effects of Apilet 80mg

During the use of Aspilet ec, you may experience some side effects, including: rash, difficulty breathing, swelling of the lips, face, tongue, throat, change in stool properties, coughing up blood, nausea and vomiting, stomach pain, fever for more than 3 days, trouble hearing, ringing in the ears, ... In addition, some other less serious side effects such as fatigue, insomnia, restlessness, problems digestive problems,... Tell your doctor or pharmacist if you experience any unusual symptoms during your treatment with Aspilet 80mg.

6. Some notes when using Aspilet ec

Caution when using Aspilets ec 80mg for the following subjects:
Patients with mild heart failure, liver and kidney disease Children: should avoid using Aspilet ec for children with viral fever, because of the potential to cause viral fever. Reye's syndrome (although rare, this is a dangerous syndrome of the liver and nervous system, which can cause coma and even death). For pregnant women: the benefits and harms of Aspilet 80mg should be considered when used in this population, because of the risk of premature closure of the ductus arteriosus and delayed labor. There is a risk of bleeding during childbirth when used in the last 3 months of pregnancy. For breastfeeding women: Aspilet ec is excreted in breast milk and may cause rashes, platelet deformities and bleeding in infants when used in high doses. Therefore, Apilet ec should not be used in this population. Apilet 80mg does not affect the ability to drive and use machines.

7. Drug interactions

Drug interactions can increase the toxicity of the drug or reduce the effect of the drug. Therefore, please list all medications you are taking (oral, injectable, vitamins, supplements, herbs, ...) for your doctor to see. At the same time, absolutely follow the doctor's instructions, do not arbitrarily increase or decrease the dose or change the route of medication to ensure the safety and effectiveness of the drug. Drugs that may interact with Aspilets ec 80mg include: anticoagulants (warfarin, heparin, ...), corticosteroids, methotrexate, valproic acid, acetazolamide, mifepristone, ginkgo biloba (an herb).
Store Aspilet ec in a dry place, at room temperature, away from direct light, out of reach of children and pets. Do not throw medicine down the toilet or plumbing.

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