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Asmacort is commonly used in the treatment of asthma and chronic bronchitis. So what is the drug Asmacort, what are the uses and how to use this drug?1. What is Asmacort?
Asmacort is a drug that acts on the respiratory tract. The drug is prepared in the form of tablets, with the main ingredient of the drug is:Dexamethasone 0.25mg. Theophylline 65mg. Phenobarbital 8.5mg. Dexamethasone has the main effect of anti-inflammatory, anti-allergic, immunosuppressive, it also has very little effect on electrolyte balance.
Theophylline has a direct effect on relaxing the smooth muscle of the bronchial tract and pulmonary blood vessels. Scientists have demonstrated that theophylline has an effect on the constriction of the normal human diaphragm, thus improving spasm in patients with chronic obstructive airways disease. In addition, theophylline is also a central respiratory stimulant.
Phenobarbital has an anticonvulsant effect - partial seizures and small seizures, prevention of recurrence of febrile seizures in infants.
Asmacort is indicated in the following cases:
Asthma, severe paroxysmal dyspnea and persistent dyspnea asthma. Spastic form of chronic bronchial disease in which the patient does not have exacerbations of respiratory decompensation. Asmacort is contraindicated in the following cases:
People with hypersensitivity to one of the components of the drug. Dexamethasone acetate is contraindicated in the following cases: Local viral infections, systemic fungal infections or tuberculosis, gonorrhea not controlled by antibacterial drugs and severely damaged joints. Theophyllin is contraindicated in the following cases: Having peptic ulcer, convulsion, uncontrolled epilepsy. Phenobarbital is contraindicated in the following cases: Severe respiratory failure, dyspnea or obstruction. Patient has porphyria. Severe liver failure. Pregnant and lactating women.
2. Dosage and how to use Asmacort
Asmacort is used by mouth.Dosage of Asmacort should be according to the doctor's instructions. The recommended dosage of Asmacort is as follows:
Adults: Use 1-2 tablets/time, 2 times/day. Children 6 - 12 years old: Use a dose of 1/2 tablet/time, 2-4 times/day. If you forget to take a dose of Asmacort, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take your next scheduled dose. Do not take a double dose of Asmacort as prescribed.
3. Side effects of Asmacort
When using Asmacort, you may experience unwanted effects including:Drowsiness. Stomach irritation, drowsiness. Long-term use can cause osteoporosis, fluid retention, hypertension, edema due to Dexamethasone. When experiencing side effects of Asmacort, you need to stop using it and notify your doctor or immediately go to the nearest medical facility for timely treatment.
4. Interactions of Asmacort with other drugs
Dexamethasone acetate in Asmacort reduces the therapeutic effect of Barbiturates, Phenytoin, Rifabutin, Rifampicin, Carbamazepine, Ephenn[W1], Aminoglutethimide and increases the hypokalemic effect when used together with potassium-lowering diuretics. blood (Thiazid, Furosemide).Theophyllin in Asmacort increases the elimination of lithium and may reduce the therapeutic effect of this drug. When co-administered with Cimetidine, high doses of Allopurinol, Propranolon, Ciprofloxacin, oral contraceptives, Erythromycin may increase serum theophyllin concentrations.
Rifampicin may decrease serum theophyllin concentrations. Theophyllin increases hepatic metabolism so it may decrease serum concentrations of either drug when co-administered with phenytoin, carbamazepine or barbiturates.
Phenobarbital in Asmacort may decrease the effectiveness of birth control pills. When phenobarbital is co-administered with beta-blockers (propranolone, metoprolol), plasma concentrations and clinical effects of beta-blockers are reduced.
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