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Arthrivit is one of the drugs indicated for symptom control in degenerative joint disease, arthritis. So when using Arthrivit, what should be noted to be effective and safe? Let's learn about Arthrivit in this article.
1. What is Arthrivit?
Arthrivit is a product of OPV Pharmaceutical Joint Stock Company, made in the form of long white film-coated tablets with the active ingredients Glucosamine sulfate potassium chloride 50 mg (equivalent to glucosamine 295.9mg) and Chondroitin sulfate sodium 400mg (equivalent to chondroitin 315.79mg).Glucosamine is found in chitin, mucopolysaccharid and mucoprotein. Glucosamine is involved in the production of glycosaminoglycans to build cartilage tissue in the body. In addition, Glucosamine is also present in ligaments and tendons. Therefore, Glucosamine is indicated in the treatment of joint diseases, including osteoarthritis. Glucosamine has anti-inflammatory activity, stimulates proteoglycan synthesis, reduces catabolic activity by inhibiting the synthesis of proteolytic enzymes and others. Chondroitin sulfate is a mucopolysaccharide acid, a structural component of most cartilage tissue. Chondroitin is sometimes used in combination with Glucosamine to have a protective effect on joints in diseases of the joints, bones and connective tissue.
In patients with osteoarthritis, Chondroitin sulfate can have anti-inflammatory effects, stimulate the synthesis of hyaluronic acid and proteoglycan, reduce the catabolism of chondrocytes by inhibiting the synthesis of proteolytic enzymes, nitric oxide and other substances. (which is responsible for the destruction of the cartilaginous raft and the death of articular chondrocytes.)
2. Indications of the drug Arthrivit
Arthrivit is indicated for the symptomatic relief of mild and moderate osteoarthritis of the knee.
3. Contraindications of Arthrivit
Do not use Arthrivit in the following cases:
Patients with hypersensitivity to Glucosamine or Chondroitin sulfate or to any of its ingredients. Patients with a history of seafood allergy should also not take Arthrivit. Women during pregnancy and lactation. Patients under 18 years of age because there are no data on the safety and efficacy of Arthrivit in this population.
4. Dosage and usage of Arthrivit
Patients over 18 years old: Take Arthrivit 3-4 tablets/day with meals, divided into 3 times a day.
Patients under 18 years of age: There are no research data on the efficacy and safety of the drug on this subject.
5. Undesirable effects of the drug Arthrivit
When taking Arthrivit, patients may experience undesirable effects such as upset stomach, nausea, vomiting, diarrhea or constipation, headache, drowsiness, skin rash, difficulty controlling blood sugar .
Patients should inform the doctor/pharmacist of any unwanted effects encountered while taking the drug.
6. Notes when using Arthrivit
When using Arthrivit, patients should pay attention to the following issues:
Caution should be exercised when using Arthrivit in patients with diabetes. Alcohol should be avoided during treatment because it can increase the drowsy effect of Arthrivit. The doctor should be informed about the use of Arthrivit if the patient is planning to have surgery. Patients should stop taking the drug and notify their doctor if they experience an allergic reaction. Arthrivit should not be used by women who are pregnant or breast-feeding. Arthrivit can cause headache, drowsiness. Therefore, patients should be careful when driving or operating machinery while taking the drug.
7. Drug interactions
Arthrivit may interact with the following drugs:
Non-steroidal anti-inflammatory drugs (NSAIDs): Arthrivit increases the effects of these drugs when taken together. Heparin, Warfarin: Do not combine with Arthrivit because of increased risk of bleeding. Insulin: Arthrivit increases insulin resistance and may affect blood glucose control in patients with diabetes. Cancer drugs (anti-mitotic drugs): Use with caution with Arthrivit. The article provides information about the uses, doses and precautions when using Arthrivit. To ensure safety for your health and maximize the effectiveness of your treatment, you need to take Arthrivit exactly as directed by your doctor. Store Arthrivit in a cool, dry place, the temperature is below 300C and avoid direct light on the product.
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