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Aranesp is a man-made protein that helps the body produce red blood cells in conditions such as kidney failure, patients on dialysis or other similar health conditions. So what is the effect of Aranesp?
1. What is the effect of Aranesp?
Aranesp, also known as darbepoetin alfa, is a man-made protein that helps the body produce red blood cells. This protein can be reduced in kidney failure or with certain medications. Aranesp is used in the treatment of a lower than normal red blood cell count such as in anemia due to chronic kidney disease in patients on dialysis and not on hemodialysis or because chemotherapy will be used for a short period of time. at least two months after starting Aranesp.Besides the above uses, Aranesp can also be used to treat some other conditions that are not listed above. Therefore, before using the drug, consult your doctor for advice and effective use of the drug.
2. How to use Aranesp
Aranesp drug is in the form of a solution for injection. The dose of Aranesp will depend on the condition and age of the patient. Usually Aranesp will be given every 1 to 4 weeks, either subcutaneously or intravenously.
For patients with chronic kidney disease who are not on dialysis, the starting dose is 0.45 mcg/kg IV or subcutaneously every 4 weeks. Do not shake the medicine, check again and do not use the changed color medicine. Initiate treatment when hemoglobin is less than 10g/dL For adults with chemotherapy-related anemia, the starting dose is 2.25mcg/kg subcutaneously once weekly or 500 mcg subcutaneously every 3 weeks. Initiate treatment if hemoglobin is less than 10g/dL and receive chemotherapy for a minimum of 2 months, using Aranesp until completion of chemotherapy. For children with anemia associated with chronic renal failure, the starting dose for non-dialysis patients is 0.45 mcg/kg IV or subcutaneously once weekly or 0.75 mcg/kg every 2 weeks. time. The starting dose for patients on dialysis is 0.45 mcg/kg subcutaneously or intravenously once weekly. Start treatment when hemoglobin is below 10g/dL. Is Aranesp good? Use Aranesp regularly to get the most benefit from it. To use the drug safely, take Aranesp exactly as directed by your doctor, medical staff, do not use too much, smaller or longer than prescribed.
3. Unwanted effects when using Aranesp
Some unwanted effects that may occur when using Aranesp include:
Low blood pressure during dialysis Cough, difficulty breathing Abdominal pain Swelling in arms or legs When using Aranesp for a long time increases the risk of heart attack and stroke. Before prescribing a drug, doctors always weigh the benefits and effects of Aranesp more than the risk of side effects. However, some cases when using Aranesp can still occur unwanted effects. Therefore, when unusual symptoms appear, especially when a severe allergic reaction occurs with accompanying signs such as difficulty breathing, severe dizziness, rash, swelling or itching of the face and throat. , tongue,... In this case, the patient should immediately notify the medical staff for immediate intervention.
4. Some notes when using Aranesp
Some notes when using Aranesp include:
Inform your doctor about a history of allergy to Aranesp or any other allergies. Aranesp may contain ingredients that don't work and could cause an allergic reaction or other serious problems. Report any medications you are taking including prescription and nonprescription drugs, herbs and supplements, foods or preservatives. Aranesp is contraindicated in patients with uncontrolled high blood pressure, a history of pure red blood cell aplasia, cardiovascular disease, heart attack, stroke, seizures,... Aranesp has May increase the likelihood of blood clots forming and cause reduced blood flow to organs or extremities and in some cases death. Therefore, it is necessary to closely monitor the hemoglobin level with blood tests during treatment with Aranesp. Tell your doctor right away if you experience severe pain, swelling in your legs, difficulty breathing, etc. Aranesp is used to treat anemia caused by chemotherapy for non-myeloid cancer. Used to treat anemia caused by cancer itself. Under certain conditions, Aranesp may cause tumors to progress or recur faster than in patients who do not take Aranesp. Aranesp may aggravate cardiovascular disease, especially in conditions such as high blood pressure, heart failure, angina or heart attack. Therefore, discuss your medical conditions with your doctor, use blood pressure medication to control your blood pressure, and monitor your hemoglobin until the right dose of Aranesp is determined. Aranesp can be used by people with chronic conditions who are on dialysis and those who are not on dialysis, the dose may be different for each person. Aranesp may increase seizures In pregnant and lactating women, there are not enough studies on the effects and risks of using Aranesp on babies. Therefore, before using the drug, consult your doctor to consider treatment. The patient should replenish the missed dose as soon as possible. However, if the time you remember is close to the time of your next dose, skip the missed dose and continue taking the medicine as scheduled. Do not arbitrarily add more than double the dose of the drug than the treatment regimen. Using an overdose of Aranesp can cause serious symptoms such as nausea, vomiting, abdominal pain, weakness,...
5. Drug interactions
Drug interactions may reduce the effect of Aranesp, or increase the effect of unwanted effects. Tell your doctor about all other medicines you are taking including vitamins, over-the-counter medicines, prescription drugs, and herbal products. Do not stop, start, or change the dose of any medicine without your doctor's consent without your doctor's consent.
Aranesp is made by medical staff at the hospital, so patients need to strictly follow the instructions for use and storage of the medicine by medical staff. In short, Aranesp is a man-made protein that helps the body produce red blood cells in patients with kidney failure, hemodialysis or cancer. However, Aranesp can cause some unwanted effects and drug interactions, so tell your doctor what medications you are taking to reduce the risk of side effects and increase effectiveness. for the treatment.
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