This is an automatically translated article.
Apolets medicine has the main ingredient is clopidogrel 75mg. The drug has the main effect of anticoagulant, inhibits platelet aggregation and dissolves thrombus. The following article will provide useful information to help you use Apolets safely and effectively.
1. Effects of Apolets
The active ingredient clopidogrel contained in Apolets when taken into the body, under the action of the enzyme CYP2C19, it is converted to a substance that selectively inhibits the process of attaching adenosine diphosphate molecules to their receptors on the surface of platelets. . As a result, the platelets do not stick together, which prevents the formation of blood clots.Because of the above mechanism of action, Apolets is prescribed by doctors for patients for the purposes of:
Prevention and prevention of events caused by atherosclerosis in cases with a history of stroke, infarction myocardial infarction and some other peripheral arterial diseases. Treatment of patients with acute coronary syndrome (with non-ST segment elevation) in combination with aspirin. Aspirin replacement therapy in patients with chronic stable angina but intolerant of aspirin. In combination with some other drugs to prevent thrombosis in coronary artery stenting, artificial heart replacement, coronary artery bypass...
2. Dosage and how to use Apolets
Dosage of Apolets is recommended as follows:
For the indications for prevention and treatment of thrombosis in adults: Use 75mg/time only during the day during or after meals. For indications for patients with acute coronary syndrome: Initial treatment with a dose of 300mg/time only on the first day, then a maintenance dose of 75mg/time/day in combination with aspirin content 75 - 325mg/day in the following days of treatment. Apolets is available in the form of film-coated tablets for oral administration.
3. Contraindications of Apolets
Do not use Apolets with the following subjects:
Patients with acute bleeding, gastrointestinal bleeding, intracranial bleeding. Patient is pregnant and lactating. Persons under 18 years old. The patient has severe liver failure. People with a history of hypersensitivity to clopidogrel or to the excipients contained in Apolets .
4. Side effects and precautions when using Apolets
A prominent side effect of Apolets is an increase in bleeding time. Because the drug inhibits coagulation, there is a risk of bleeding, especially gastrointestinal bleeding or intraocular bleeding in patients with potentially hemorrhagic lesions. So use extreme caution when using Apolets for these objects.
In addition, patients using Apolets may experience symptoms such as stomach pain, diarrhea, skin rash, thrombocytopenia, etc. However, the incidence of these symptoms is quite rare. .
To prevent antiplatelet effects during surgery, patients should stop taking Apolets about 5 days before the day of surgery.
Apolets should not be used in patients with acute myocardial infarction in the first days after detection.
5. Apolets Drug Interactions
Concomitant use of Apolets and warfarin may increase the anticoagulant effect, thereby increasing the risk of bleeding. The same happens when Apolets is combined with NSAIDs, aspirin or other anticoagulants such as heparin. Therefore, you need to inform your doctor if you are using the above drugs to receive advice and adjust the dose of Apolets at the most appropriate level.
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