This is an automatically translated article.
In cancer treatment there are many stages where the patient can be nauseated as a side effect of drugs or chemotherapy. Therefore, to prevent and limit this situation, patients can be prescribed Anzemet with the active ingredient Dolasetron, which has antiemetic effects.
1. How does Anzemet work?
Anzemet has the main active ingredient, Dolasetron, which works by inhibiting the effect of serotonin - a chemical transmitter that causes nausea to prevent vomiting caused by chemotherapy. However, it should be noted that Anzemet is not effective in preventing radiotherapy-induced nausea and Anzemet oral tablets should not be used to prevent postoperative nausea due to an increased risk of serious side effects, so people Patients should use injectable Dolasetron.
2. How to use Anzemet?
Anzemet is usually taken by mouth with or without food 1 hour before the start of cancer treatment with chemotherapy. Meanwhile, if using Anzemet injection form, it can be used about 2 hours before surgery. For children, the dose of Anzemet will be calculated by weight and monitored by the doctor, absolutely do not arbitrarily increase the dose if it does not have the desired effect or prolong the time of taking the drug longer than that. point.
3. Some notes when using Anzemet:
Like other drugs, after using Anzemet patients may experience some side effects such as:
Headache, fatigue Diarrhea Dizziness or dizziness Abdominal pain Changes in vision Chest pain Severe dizziness or fainting Fast, slow or irregular heart rate Serotonin toxicity syndrome: because Anzemet has the ability to increase blood serotonin, if the patient takes it in combination with other drugs that also increase this active substance, it may lead to syndrome. this condition with severe symptoms. Anzemet rarely causes serious allergic reactions when used for treatment, but when there are signs of rash, itching, swelling of the lips and skin, it is also necessary to contact a doctor for timely treatment. Use of Anzemet:
Patients should talk to their doctor if there is a history of allergy to Dolasetron or other anti-nausea serotonin inhibitors (granisetron, ondansetron) Dolasetron may affect heart rate (prolonged QT interval) causing If you experience arrhythmia or irregular heartbeat, fainting, or dizziness, you should notify your doctor if you have any similar symptoms Low levels of potassium or magnesium in the blood may increase the risk of QT prolongation, especially in patients with Patients who are taking diuretics or are in a state of dehydration (diarrhea, vomiting) Children and the elderly are susceptible to the side effects of Anzemet, especially in the presence of cardiovascular disease. follow. Therefore, extreme caution should be exercised when using Anzemet in these patients.
4. Drug interactions with Anzemet:
Some drug interactions to watch out for when used with Anzemet include:
Apomorphine Drugs that can slow the heart rate (beta blockers like atenolol, calcium blockers like verapamil) Drugs that affect heart rate (QT prolongation) such as: : amiodarone, dofetilide, flecainide, pimozide, procainamide, quinidine, ziprasidone. Drugs, ecstasy, antidepressants when used together with Anzemet can cause serotonin poisoning syndrome The above are the main uses of Anzemet. Actively refer to and understand the information about the drug will help the process of using it more effectively and safely for the patient.
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