This is an automatically translated article.
Zarxio is a man-made form of human granulocyte colony-stimulating factor (G-CSF), whose main ingredient is Filgrastim. The purpose of G-CSF is to stimulate the growth of neutrophils, thereby protecting the body from infection.
1. What is Zarxio?
The main ingredient of Zarxio is Filgrastim, a man-made version of G-CSF - a certain natural substance made in the human body. They stimulate the body to produce more white blood cells. White blood cells play an important role in the body's fight against infections.With its effect, the drug Zarxio is usually indicated for use in the following subjects:
People with impaired white blood cell production (eg, due to chemotherapy, chronic leukopenia, exposure to high amounts of large radiation); Support for certain treatment cases (bone marrow transplant/stem cell transplant).
2. Instructions on how to use Zarxio
Depending on the dosage form, Zarxio can be injected under the skin or into a vein. Users strictly follow the doctor's instructions, usually 1 time / day. In addition, the dose is also considered based on your medical condition, weight, test results and response to treatment.
Notes on drug administration
If you are using subcutaneous injection, take the medicine out of the refrigerator at least 30 minutes before injecting to bring the medicine to room temperature; Do not shake the medicine. Observe with the naked eye for signs of precipitation or discoloration. If abnormality is found, do not use the product; Before injecting, it is necessary to clean the injection site with antiseptic alcohol. Change the injection site each time differently to reduce subcutaneous lesions; Do not inject Zarxio into areas of skin that are bruised, tender, red, hard, scarred or stretch marks; Zarxio should be used regularly to increase the effectiveness of treatment. It will be easier if you take your medicine at the same time every day; If you are undergoing chemotherapy for cancer, you should not take this medicine 24 hours before or after chemotherapy. Ask your doctor for specific instructions on when to take the medication.
3. Side effects of the drug Zarxio
During treatment with Zarxio, users may experience side effects such as:
Pain in bones and muscles; swelling, redness, itching, or bruising at the injection site; Easy bleeding, bruising; Pink urine, bloody urine; Vomiting, coughing up blood; heart palpitations, fever; Purple or red spots on the skin; Backache; Get emergency medical help if you experience very serious side effects such as:
Respiratory problems (difficulty breathing, rapid breathing, rapid breathing); Abnormal decrease in urination; Unusual fatigue; Body swelling. In rare cases, severe spleen damage (spleen rupture) can lead to death. Call 911 immediately if you experience stomach, abdominal or left shoulder pain;
Also, very rarely, this medicine may increase your risk of developing a bone marrow disorder (myelodysplastic syndrome - MDS) or blood cancer (acute myeloid leukemia - AML). ) in people with congenital neutropenia, breast cancer or lung cancer patients receiving chemotherapy/radiotherapy.
4. Notes when using the drug Zarxio
Contraindicated to use Zarxio drug for people with severe allergy to ingredients Filgrastim or Pegfilgrastim;
Before treatment with this medicine, tell your doctor all about your medical history, especially if you have the following:
Sickle cell disease ; Have kidney problems; Undergoing radiation therapy; Are pregnant or planning to become pregnant (it is not known how the drug affects the fetus); Are breastfeeding or planning to breastfeed (it is not known whether this medicine passes into breast milk); Are taking a variety of medications such as vitamins, over-the-counter medicines, herbs.
5. Zarxio drug interactions
The ingredient Filgrastim in Zarxio is very similar to Pegfilgrastim. To avoid unwanted side effects, avoid taking pegfilgrastim products while using Zarxio.
Zarxio may affect the results of certain laboratory tests (such as bone imaging). So make sure laboratory staff and doctors know you are using this medicine.
Hope the above sharing has helped you better understand the drug Zarxio with the same use. If you have any further questions, you can contact your doctor for in-depth advice.
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