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Anagrelide is a medicine that prevents the body from producing too many platelets in the blood, so it is used to treat conditions that cause high platelets in the blood. Treatment reduces the risk of complications caused by thrombocytosis, which causes unnecessary blood clots in the body.
1. Anagrelide drug use
Anagrelide is available in the form of capsules with strengths of 0.5mg and 1mg. This medication Anagrelide is used to treat a blood cell disorder that causes thrombocytosis, which occurs when your bone marrow produces too many platelet cells. Platelets are a type of blood cell produced and used by the body to participate in the clotting process, to form blood clots to help reduce bleeding. When the body has too many platelets produced, it can lead to the appearance of unnecessary blood clots and cause blockage of blood flow, lack of blood to organs in the body.
Anagrelide helps lower the number of platelets in the blood by stopping the body from making them.
2. How to take Anagrelide
Anagrelide is an oral medication, so you need to take it with water and can be taken with or without food. Usually, the drug is used at a dose depending on the condition of the disease, the ability to tolerate the drug.
Adults usually take 1mg/time and 2 or 0.5mg/time and 4 times a day or as directed by a physician. Children or people with liver disease can start with 1 dose per day. Dosage adjustments will likely be changed once a week (no more than 0.5mg per day) to find the best dose to keep platelets close to normal. Single doses of more than 2.5 mg or more than a total of 10 mg should not be taken in a single day. Note: Take the medicine regularly for the best effect. It is best to take the medicine at the same time each day to remember the dose, if you forget or take it as soon as you remember, and do not take a double dose next time. Do not stop taking your medication without consulting your doctor, as stopping anagrelide suddenly can cause your platelet count to rise again.
3. Anagride side effects
As with other medicines, taking Anagride can cause side effects:
Get medical help right away if you have signs of a serious allergic reaction: Hives ; shortness of breath; Severe abdominal pain; confusion; swelling of the face, lips, tongue, or throat. Stop the medicine and call your doctor at once if any of these serious side effects occur: Easy bruising or bleeding such as nosebleeds, bleeding gums; signs of stomach bleeding include bloody or coffee-colored stools, coughing up blood or vomit that looks like coffee grounds; chest pain or heaviness in the chest; very fast or pounding heartbeats, sudden dizziness, fainting; short of breath; swelling in your lower leg; or blue lips or skin. Less serious common side effects may include: Tachycardia ; numbness, tingling, burning pain; headache, weakness, fatigue, dizziness; stomach pain, bloating, indigestion, loss of appetite; nausea and vomiting diarrhea; swelling in your hands or feet; fever, cough, body aches... Sometimes you may also experience other side effects, if you feel worried please inform your doctor immediately for advice.
4. Some things to note when taking Anagrelide
Do not take Anagrelide if you have a history of allergy to any of its ingredients. This medicine must not be used in children under 7 years of age, because the risk of harm to the child is not known.
Before taking it, you need to tell your doctor about any allergies to the medicine and any medical problems, as this can affect the use of the medicine and the risk of side effects increases, especially:
Problems with bleeding disorders; High risk of long QT syndrome (in you or possibly a family member); Medical problems in the heart or lungs; Liver disease ; Electrolyte imbalance : such as low blood sodium or potassium... For pregnant women: It is not known whether taking anagrelide will harm an unborn baby. Therefore, it should not be used unnecessarily and before taking this medicine you need to tell your doctor if you are pregnant or planning to become pregnant so that the doctor can weigh the benefits and risks to the fetus. Also, taking this medicine may affect your fertility, so talk to your doctor about your plans to have children.
Because the drug can pass into breast milk and affect the nursing infant. Therefore, you should not breast-feed while taking anagrelide. Periodic monitoring of blood tests and electrocardiograms during drug administration. If you have to undergo any surgery, tell the surgeon you are taking Anagrelide so that it can be considered or stopped. Drug interactions: Do not take aspirin unless directed by your doctor and other non-steroidal anti-inflammatory drugs such as ibuprofen, ketoprofen or naproxen... as it may increase the risk of bleeding.
Above is information about the effects of Anagrelide. This is a prescription drug, so patients should only use it when prescribed by a doctor and if you have any questions, you should consult your doctor directly for effective use.
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Reference source: drugs.com