This is an automatically translated article.
Amtrinil belongs to the group of psychotropic drugs, used to treat a number of mental and behavioral disorders. The drug Amitrinil is used under the direction of the treating doctor.
1. What is Amitrinil?
Amitrinil medicine has the main active ingredient Amisulpride 400mg and other excipients just enough. The drug is prepared in the form of film-coated tablets, packed into boxes, boxes of 1 blister x 10 tablets and boxes of 3 blisters x 10 tablets.
2. Uses of Amitrinil
2.1. Uses - indications of Amitrinil Amitrinil is used to treat the following cases: People suffering from mental diseases, acute and chronic schizophrenic disorders with symptoms such as paranoia, confusion disordered thinking, hallucinations, .... and/or no symptoms such as preferring to live in isolation, not expressing emotions.
2.2. Contraindications Amitrinil Amitrinil is contraindicated for use in the following cases:
People who are allergic or hypersensitive to the Amisulpride component contained in the drug. People with suspected or confirmed pheochromocytoma. Children under 15 years old because there are not enough clinical data on the use of drugs for these subjects. People with suspected or confirmed prolactin-dependent tumors, typically pituitary adenoma and breast cancer People with severe renal impairment, with creatinine clearance less than 10ml/min People with Levodopa disease, pregnant women or are in the process of breastfeeding. Note: the cases of contraindications to the use of Amtrinil should be understood as absolute contraindications, ie not for any reason that the above cases can be used flexibly.
3. Usage and dosage of Amtrinil
How to use: Amtrinil is prepared in the form of film-coated tablets should be used orally, combined with a sufficient amount of filtered water. Patients should avoid breaking, crushing or combining drinking with alcohol, carbonated drinks so as not to affect the ingredients in the drug.
Dosage:
Recommended dose: Use from 50 to 300mg / day, adjust the dose according to the condition of each patient. The optimal recommended dose is in the range of 100mg/day. For people in the period with both negative and positive symptoms: starting dose of 400 to 800mg/day, then adjust the dose of Amtrinil according to the individual patient's ability to respond to the drug to achieve the maximum dose. minimally effective. Treatment of acute psychotic episodes: Initial dose: At the recommended dose of 400 to 800 mg/day, an effective therapeutic dose can be used right from the start without the need for an exploratory dose. Note, not to exceed 1200mg/day. Subsequent dose: The dose can be maintained or adjusted to suit the patient's ability to respond to the drug. It is recommended to find the minimum effective dose for each patient in all cases. For patients with renal impairment: Reduce dose by 1/2 for patients with renal failure with creatinine clearance from 30 to 60 ml/min. Reduce dose by 1/3 for patients with renal impairment with creatinine clearance between 10 and 30ml/min. Amtrinil is contraindicated in patients with renal impairment with creatinine clearance less than 10 minutes due to lack of dosing data in this population. For patients with hepatic impairment: No dose reduction is necessary in this patient because amisulpride is poorly metabolized. In case of missed dose: Users can take it as soon as they remember if it is 4-6 hours apart from the next dose. If the time is too close, skip the missed dose and use the next dose exactly as directed by your doctor. Do not use double the number of doses to make up for the missed dose of Amtrinil, to avoid leading to an overdose.
In case of overdose: Currently, there are no reports of reactions occurring when using Amtrinil overdose. However, if you find yourself using an overdose and have unusual symptoms, contact your doctor immediately, clearly informing the dose you have used and your current condition for timely support. time.
4. Amtrinil side effects
During use, in addition to the main use that Amtrinil brings, users may also experience some unwanted effects as follows:
Common cases:
Causes some clinical manifestations such as: : Hyperprolactinemia, increased lactation, breast engorgement, breast enlargement in men, impotence, frigidity. Usually these symptoms go away when the drug is stopped. Weight gain Rare cases:
Causes some extrapyramidal symptoms: Increased salivation, increased tone, vibration, restlessness, movement disorders. Drowsiness Causes digestive disorders such as: Nausea, vomiting, dry mouth, constipation Extremely rare cases:
Causes acute dystonia: Neck twisting, eye rotation, jaw tightness, ... Causes tardive dyskinesia, involuntary movements of the tongue or eyes Causes low blood pressure, bradycardia Causes allergic symptoms on the skin Causes convulsions Occurrence of certain malignant syndromes Note : If you experience any of the above symptoms or any other symptoms commonly suspected of using Amtrinil, you should immediately notify your doctor for instructions on how to handle it safely and effectively.
5. Amtrinil drug interactions
Users need to keep in mind some notes about the interactions between Amtrinil and other drugs as follows:
Absolutely do not use alcohol, beer, drugs containing Levodopa during the treatment period. Do not use in combination with antihypertensive drugs, anxiolytics, antidepressants, morphine derivatives, antihistamines, hypnotics, barbiturates, benzodiazepines or other sedatives. Note: In order to minimize the unfortunate interactions that occur, users should inform their doctor about the drugs, functional foods that they are using or intend to use with Amtrinil to get the right treatment. the most appropriate course of treatment.
6. Some notes when using Amtrinil
When using Amtrinil, patients should note a few things:
Be careful when using the drug for people with severe kidney failure, epilepsy or Parkinson's disease. Pay attention when using the drug with people who are driving, train or operating machinery. For women who are pregnant or breast-feeding, it is necessary to consult a doctor before use, only use when absolutely necessary, when the effectiveness of Amtrinil medicine outweighs the possible risks. happen. Hopefully, the information shared above about Amtrinil will help patients get more useful information in the process of treating mental and behavioral disorders. Note that Amtrinil is a prescription drug, so patients should not use it on their own, but need to contact a doctor/pharmacist directly to get a suitable prescription and ensure safety for health.
