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Amribazine belongs to the group of anti-parasitic, anti-infective, anti-viral, anti-fungal drugs. Let's learn more about the uses and uses of Amribazine through the article below.1. What is Amribazine?
Amribazine medicine has the main ingredient containing the active ingredient Ribavirin with the content of 500mg and the excipients just enough for 1 tablet. The drug is prepared in the form of film-coated tablets, packed in boxes of 3 blisters, each blister contains 10 tablets.
2. Effects of Amribazine
The active ingredient Ribavirin is active in vitro against at least 20 different DNA and RNA viruses. There is evidence to demonstrate a broad spectrum of activity against both viruses of this active substance. Based on clinical evaluations that have demonstrated the efficacy of the drug in different formulations and by different routes of administration against diseases such as hepatitis C, hepatitis B, hepatitis vi A, Herpes zoster, Herpes simplex type I and type II . Or chickenpox, measles, influenza A and influenza B, viruses that cause hemorrhagic fever, respiratory syncytial virus (RSV).Amribazin is indicated for use in the following cases:
Treatment of viral hepatitis: Amribazine is indicated in viral hepatitis such as hepatitis C, hepatitis B, viral hepatitis A. Indications for the treatment of Herpes Zoster / Simplex virus infections such as: Herpes genitalis, Herpes Labialis, Herpes Zoste, Herpes gingivostomatitis. Treatment in flu (influenza): Amribazine is used to shorten the duration of illness in patients with influenza infection. However, there is still no specific treatment that can be used to treat influenza B. Indications for use in other viral infections in children such as chickenpox, mumps, measles, sugar syncytial virus. respiratory and other diseases.
3. Usage and dosage of Amribazine
3.1. How to use Amribazin Amribazin drug is prepared in the form of film-coated tablets, used orally, the duration of drug use does not depend on the meal.
3.2. Dosage of the drug Amribazin In adults:
Hepatitis A: use a dose of 800 mg/day, use 3-4 times a day, use within 10 to 14 days. Hepatitis B and hepatitis C: use dose 800-1200 mg/day, use 3-4 times a day, duration of use lasts from 6 months to 1 year. Herpes Zoster virus / Simplex: use a dose of 800 - 1200 mg / day, use 3-4 times a day, use it for 7 to 10 days. In the prevention of recurrence of genital herpes: 400 mg/day, 1-2 times a day, prolonged treatment for 6 months. It is possible to divide the dose based on body weight, indicated for use at a dose of 15 mg/kg body weight/day, 3 to 4 times a day. This dosage is for reference only, it is recommended that patients must strictly follow the treatment regimen of the doctor to achieve high effectiveness in treatment, do not arbitrarily adjust the dose or stop using the drug when Haven't consulted a doctor.
4. Undesirable effects of the drug Amribazine
The possible side effects for patients during treatment with Amribazine are as follows: Nausea, muscle pain, itching, fatigue (these symptoms can be reversed when the patient stops using the drug). ), mild hemolytic anemia, increased uric acid, increased serum bilirubin, central nervous system disorders, digestive system disorders.
Although the undesirable effects are usually only mild, transient and reversible after stopping treatment with Amribazine, it is recommended that patients immediately notify the treating doctor when experiencing unusual signs for guidance on treatment. effective management.
5. Amribazine drug interactions
When two or more drugs are used at the same time, drug interactions often lead to synergistic or antagonistic phenomena.
When systemic administration of Amribazine with Dideoxyinosine (ddI) was found to be synergistic in HIV suppression. The use of tobacco, alcohol, alcoholic beverages or fermentation should be avoided during treatment with Amribazine, because these agents can cause changes in the substances contained in the drug leading to synergism. or drug resistance. It is recommended that patients need to list drugs and functional foods that have been used recently with the treating doctor so that they can have appropriate indications for drug use and avoid unwanted effects. wish could happen.
6. Notes when using Amribazine
6.1. Contraindications of Amribazin is not indicated for the use of Amribazin in the following cases:
Patients with impaired renal function, severe renal failure with creatinine clearance less than 30 ml/min. Patients with chronic anemia have HB levels below 10 g/dl. Patients with a history of hypersensitivity to Ribavirin or to any of the excipients of Amribazine. Amribazine should not be used in pregnant women and lactating mothers, studies have shown that the drug has teratogenic effects in animals and the drug can be passed into breast milk. Absolutely do not use Amribazine on these subjects. 6.2. Caution when using Amribazine should be used with caution in patients with advanced renal failure, cirrhosis of the liver. For patients with anemia: it is necessary to stop treatment for 2 weeks, if the anemia improves, the dose can be resumed, if not, reduce it to 200 mg/day. Effective contraception should be used while using Amribazine, for at least 6 months after stopping treatment in both men and women.
7. Preservation of Amribazine
Store Amribazine in a cool, dry place, avoid direct sunlight or high temperature, these agents can cause the change of active ingredients in the drug, causing change the therapeutic effect of the drug, the appropriate storage temperature is below 30 degrees C.
It is recommended that users carefully read the instructions and expiry date before use. If there are organoleptic changes such as color change, mold or watery appearance, do not continue to use the pack. Keep out of reach of children, avoid incidents of misuse of drugs, causing unwanted effects.
Hopefully with the sharing of the use of Amribazine, it will help users to use it effectively and safely during the treatment of the disease.
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