This is an automatically translated article.
The article was professionally consulted with Specialist Doctor Obstetrician and Gynecologist - Department of Obstetrics and Gynecology - Vinmec Hai Phong International General Hospital.
Ammedroxi 150mg drug has the active ingredient Roxithromycin in the group of macrolide antibiotics. What are the uses of Ammedroxi? Please refer to the article below!
1. What are the effects of Ammedroxi 150mg?
This is the question of many people when seeing that Ammedroxi is used very commonly. Specifically, Ammedroxi 150mg is indicated in cases of infections caused by strains identified as sensitive to antibiotics:
What does Ammedroxi 150mg do? Treatment of infections and infections of the upper respiratory tract such as: pharyngitis, tonsillitis... Lower respiratory tract infections such as: pneumonia, bronchitis,... Skin and soft tissue infections Ammedroxi drug 150mg treatment of oral infections such as: gingivitis, pulpitis... Infections of the genital organs in women such as: cervicitis, vaginitis... Regarding pharmacodynamics, Roxithromycine in This drug is a semi-synthetic antibiotic belonging to the macrolide family.
Pharmacokinetics: Roxithromycin has good penetration into the cells and cavities of the body and reaches high concentrations in the lungs. However, Roxithromycin does not cross the blood-brain barrier and is eliminated primarily by hepatic metabolism and metabolites are excreted in the bile and faeces. Ammedroxi medicine 150mg can be prescribed for people with renal insufficiency.
2. Contraindications of Ammedroxi
Ammedroxi is an antibiotic, so in some cases, patients are not allowed to prescribe such as:
Patients with hypersensitivity to the macrolide group. Patients with hypersensitivity to any ingredient of the drug Ammedroxi is contraindicated with ergot alkaloids that cause vasoconstriction (ergotamine and dihydroergotamine). The patient has a history of hypersensitivity to macrolide antibiotics. Ammedroxi may interact with roxithromycin with ergotamine-type vasoconstrictor compounds. Roxithromycin and other macrolides should not be used in patients receiving terfenadine or astemisol because of the risk of life-threatening arrhythmias. The combination of macrolides with cisapride is contraindicated, due to the risk of severe arrhythmias.
3. Usage and dosage of Ammedroxi
3.1.How to take Ammedroxi 150mg is used orally. Patients can be taken with or without food as prescribed by the doctor, the drug is usually used 2 times a day in the morning and evening.
After using the medicine for a few days, your symptoms may go away but you still need to take the full amount of medicine as prescribed by your doctor for the rest of the course.
If you have finished taking Ammedroxi medicine but your symptoms do not improve or tend to get worse, you need to notify your doctor for appropriate treatment.
3.2. Dosage For adults, the daily dose is 150 mg. Should not be used for more than 10 days. For children use the usual dose: 5-8 mg/kg/day. By weight: 6-11kg: 25 mg, taken 2 times/day; 12 – 23 kg: 50 mg, orally 2 times a day; 24-40 kg: 100 mg, orally twice a day. Patients with severe hepatic impairment: The dose must be reduced by 1/2 of the normal dose. Renal impairment: No need to change the usual dose.
4. Undesirable effects
Some side effects patients may encounter during the use of Ammedroxi medicine such as nausea, vomiting, epigastric pain, diarrhea. Less common side effects include: Rash, urticaria, angioedema, purpura, bronchospasm, anaphylaxis, dizziness, headache, paresthesia, decreased sense of smell and/or sense of smell. or taste, increased drug-resistant bacteria, superinfection. Some side effects are rarer, but if the patient does not use the drug properly, it is still possible to encounter such as: increase in serum liver enzymes, cholestatic hepatitis, .. Mild adverse reactions, the patient only needs to stop the drug. With more severe side effects, patients need to receive treatment support from medical facilities.
5. Be careful when using Ammedroxi
Ammedroxi drug can be used for subjects with liver failure but need to be careful about the dosage. Patients need to inform their doctor about their liver condition, the doctor can adjust the dose and use. Drivers and machine operators need to consult a doctor about the precautions when taking Ammedroxi Although there are no reports that the use of Ammedroxi drug affects pregnancy and fetal health. . However, pregnant women only use the drug when absolutely necessary and under the guidance of a doctor.
6. Drug interactions
Concerns that Ammedroxi may interact with warfarin, carbamazepine, ciclosporin and oral contraceptives were explained as negligible. Ammedroxi may cause a slight increase in theophylline or ciclosporin plasma concentrations, but the physician may or may not need to adjust the dose. Ammedroxi may increase serum concentrations of unbound disopyramide. Experts recommend not combining roxithromycin with one of the following drugs: astemisol, terfenadine, cisapride, which has the potential to cause serious cardiac arrhythmias. Ammedroxi has been shown to be effective in the treatment of diseases associated with bacterial infections. The safe use of drugs not only shortens the treatment time, but also reduces the risk of unwanted side effects.
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