Learn about the drug Azicine 250mg

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1. Uses of Azicine 250mg

Azicine 250mg belongs to the group of antifungal drugs, with the main active ingredient being Azithromycin. This active ingredient inhibits bacterial protein synthesis and prevents translocation of peptides. Azithromycin is sensitive to typical bacterial strains such as Gram-positive and Gram-negative aerobic bacteria, anaerobic bacteria and other strains of bacteria.
Azicine antibiotic is made in the form of nuggets and tablets. Azithromycin 1.5mg pack and tablets both contain Azithromycin 250mg. The use of Azicine 250mg is to treat the following cases:
Upper respiratory tract infections: Ear - nose - throat infections such as otitis media, sinusitis, tonsillitis, ... Lower respiratory tract infections: Acute bronchitis, pneumonia, acute superinfection in chronic obstructive pulmonary disease (COPD), community-acquired pneumonia (CAP) of mild and moderate severity. Infections of the skin and subcutaneous structures, soft tissues: Pustules, boils, impetigo. Genitourinary and urinary tract infections: Cervicitis, urethritis. Treatment and prevention of disseminated infections in HIV patients.

2. Dosage and how to use Azicine 250mg

How to take Azicine 250mg depends on the dosage form. For Azicine sachets need to be dissolved with warm water to drink, and tablets are swallowed whole with water or not. It is best to take the medicine at least 1 hour before eating or at least 2 hours after eating.
Dosage of antibiotic Azicine 250mg for adults (over 16 years old) is as follows:
Upper and lower respiratory tract infections (including pharyngitis, tonsillitis, superinfection in chronic obstructive pulmonary disease from mild to mild). To moderate to moderate, community-acquired pneumonia), skin and skin structure infections: Initial dose is 500mg/time/day for the first day (single dose only), then 250mg/time/day and use in 4 days. The total dose is 1.5g. Upper respiratory tract infection is acute sinusitis: Azicine antibiotic 500mg/time/day, used for 3 days. Skin infections are chancroid: 1g/time, use a single dose. Genitourinary and urinary tract infections are sexually transmitted diseases, cervicitis, urinary tract infections: 1-2g/time depending on the strain of bacteria, use a single dose. Disseminated infections in people with HIV disease: Primary prevention is using the antibiotic Azicine at a dose of 1.2g/time/week (it can be used alone or in combination with rifabutin); diffuse treatment using dose 600mg/time/day in combination with ethambutol 15mg/kg/day; Prevention of infection recurrence: 500 mg/time/day in combination with ethambutol 15 mg/kg/day with or without rifabutin 300 mg/time/day. HIV-negative disseminated pulmonary infection: 250 - 500 mg/times 3 times/week in combination with rifabutin 300 mg/day or rifampin 600 mg/day and ethambutol 25 mg/kg/day for 2 months and then ethambutol 15 mg /kg/day. The dose of antibiotic Azicine 250mg for children is 10mg/kg/day, used for 3 days or 10mg/kg/day first, then 5mg/kg/time/day for the next 4 days.
Depending on the condition and the progression of the disease, the dose may be different. To ensure the safety and effectiveness of treatment, it is best to consult a doctor to be prescribed the appropriate dose.
Azicine antibiotic, if used in excess, can cause typical symptoms such as nausea, vomiting, diarrhea, and hearing loss. At that time, the patient should be treated symptomatically and supported with other measures if necessary.

3. Side effects of Azicine 250mg

Azicine 250mg can cause some unwanted side effects with the following frequency:
Common: Manifestations of digestive disorders such as abdominal pain, nausea, vomiting, diarrhea. Uncommon: Headache, fatigue, somnolence, dizziness, loss of appetite, flatulence, dyspepsia, pruritus, rash, cervicitis, vaginitis. Rare: Angioedema, anaphylactic reactions, increased transaminases, transient neutropenia. If you see any of the above side effects after taking Azicine 250mg, the patient should stop taking the drug and handle it properly in time, by going to a medical facility or contacting a doctor.

4. Some notes when using Azicine 250mg

Azicine 250mg medicine is used for people who are sensitive to the ingredients of the drug, infants under 6 months old. People with liver failure need to be careful in taking the drug because the drug is mainly eliminated through the liver. People with severe renal failure, glomerular filtration rate <10ml/min should be careful when using Azicine antibiotics. The drug is only used in the treatment and prevention of infections with susceptible strains of bacteria to limit drug resistance and effective treatment. People with fructose intolerance, sucrase-isomaltase enzyme deficiency or glucose-galactose malabsorption should not take the antibiotic Azicine, because it contains sucrose. People with phenylketonuria (PKU) should not take the antibiotic Azicine, because it is harmful to the patient. If you see symptoms of headache, dizziness, fatigue, drowsiness after taking Azicine 250mg, you should limit driving or operating machinery. Pregnant women should only use Azicine 250mg in case of absolute necessity, but nursing women should be cautious, because the drug is excreted in breast milk. The antibiotic Azicine may interact with drugs including anticoagulants, digitalis glycosides, ergotamine and dihydroergotamine, triazolam and drugs that are metabolised via the cytochrome P450 system. Azicine medicine 250mg is used in the treatment of infections of the upper respiratory tract, lower respiratory tract, infections of the skin and subcutaneous structures, urinary-genital tract infections, treatment and prevention of disseminated infections in people with HIV infection. To ensure the effectiveness of the treatment, the patient needs to take the medicine exactly as directed by the doctor.
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