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What is Amlobest? Amlobest is a cardiovascular drug with the ingredient Amlodipine (as Amlodipine besilate) 5 mg. The drug is used for people with diabetes, gout and asthma.
1. What are the uses of Amlobest?
Amlobest is indicated for use in the following cases:
Treatment of hypertension (when the patient has metabolic complications such as diabetes) and also for prophylaxis in patients with angina stability. Amlodipine reduces coronary vasoconstriction, dilates peripheral arterioles and leads to a reduction in both peripheral resistance directly acting on cardiac contractility (afterload). This offloading effect reduces myocardial energy consumption and reduces oxygen demand. The use of Amlobest is contraindicated in the following cases:
Patients with heart failure who have not been stabilized. Patients with hypersensitivity to dihydropyridine.
2. Dosage and usage of Amlobest
For the treatment of hypertension and angina, the dose must be appropriate for the individual patient. If the effect of the drug is not effective after 4 consecutive weeks of treatment, the patient can increase the dose without adjusting the dose when co-administering thiazide diuretics. Dosage of Amlobest is as follows:
Adults: According to the dosing instructions for adults, it is taken orally. Start with a normal dose of 5 mg once for 24 hours. The dose may be increased to 10 mg once daily. Children: Need to consult a doctor about dosage and use. If in the case of taking Amlobest, the patient forgets a dose while taking it, take it back as soon as possible (usually it can be taken 1 to 2 hours before the time ordered by the doctor). However, if it is almost time for your next dose, skip the missed dose and take your next dose at the time prescribed by your doctor. Never take more than double the prescribed dose.
In patients, there are limited cases of intentional overdose. Available drug information indicates that overdosage (above 100 mg) is associated with excessive peripheral vasodilatation, resulting in systemic and possibly prolonged hypotension. For symptoms of hypotension due to overdose of amlodipine, it is necessary to have active cardiovascular support measures. Intravenous administration of calcium gluconate may reverse the calcium channel blocking effect. Because amlodipine is highly protein bound, dialysis is virtually ineffectual.
3. Note when using Amlobest
When using Amlobest, caution should be exercised in patients with reduced liver function, aortic stenosis and heart failure after acute myocardial infarction. Care should be taken when increasing the dose in elderly patients. The drug should not be used in children without clinical experience. Keep out of reach of children. Amlobest drugs used during pregnancy will cause adverse effects leading to teratogens, miscarriage or fetal malformations...). When it comes to any stage of pregnancy, especially in the first trimester. Therefore, the drug should not be used by pregnant women. If you must take it, consult your doctor or pharmacist before deciding to take it. Amlobest drug can be passed to the baby through breastfeeding, so it is best not to or can limit taking the drug during breastfeeding.
4. Amlobest drug side effects
In general, Amlodipine is well tolerated. The most common side effects are: fatigue, drowsiness, headache, edema, nausea, abdominal pain, nervousness, dizziness and flushing.
5. Amlobest drug interactions
The case where Amlobest interacts with other drugs is often quite complicated due to the influence of many ingredients in the drug. According to studies or recommendations, often indicate common interactions when used. Therefore, do not arbitrarily apply the information about the interaction of Amlobest if the patient is not a doctor or a person working related to medicine.
Amlobest drug should be considered when using together with tobacco, alcohol, alcoholic or fermented drinks. Many agents can change the composition of a drug. Need to see details in the drug leaflet or you can consult a doctor, pharmacist for instructions.
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