Uses of Amisulpride 200mg

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1. What is Amisulpride?

What is Amisulpride? Amisulpride drug, also known as aminosultopride, amisulprida, belongs to a group of atypical antipsychotic drugs, antiemetic drugs are made in the form of intravenous solution with the strength of 5mg/2mg and the tablet form is Amisulpride 200mg and 400mg . Amisulpride has the main active ingredient, Amisulpride, which works by blocking the action of a chemical in the brain that affects thinking, behavior, and feeling.

2. Indications and contraindications of Amisulpride

2.1 Indications for use of Amisulpride Drugs Indications to use Amisulpride are:
Intravenous form indicated in case of nausea or vomiting after surgery. Tablets are used to treat acute or chronic schizophrenia accompanied by symptoms such as hallucinations, delusions, or thought disturbances. 2.2 Contraindications to the use of Amisulpride The cases of contraindications to the use of Amisulpride such as:
Coma CNS depression Coronary tumor in the adrenal gland Excessive epinephrine secretion Hypersensitivity to the components of the drug Pituitary prolactin tumor Pheochromocytoma tumor Prolactin dependent tumor such as breast cancer Children under 18 years of age, pregnant and lactating women

3. Usage and dosage of Amisulpride

Amisulpride is made in the form of tablets and intravenous solution, so it can be administered orally and intravenously. Dosage depends on age and disease status as follows:
For adults to treat nausea and vomiting after surgery will be used injection form with a prophylactic dose of 5mg and a therapeutic dose of 10mg. In the treatment of acute psychotic episodes, use a dose of 400-800mg/day divided into 2 oral doses. The maximum dose is 1200mg/day. Use Amisulpride regularly to get the most benefit from it. To use this medicine safely, take Amisulpride exactly as directed by your doctor, do not use it more often, for less or for longer than prescribed. Absolutely do not abuse the drug for too long for a long time or arbitrarily increase the dose of the drug. Because this not only makes the condition worse, but also increases the risk of unwanted effects.

4. Undesirable effects when using Amisulpride drug

Some unwanted effects that may occur when using Amisulpride include:
Insomnia Anxiety Agitation Somnolence Constipation Diarrhea Nausea Vomiting Dry mouth Weight gain Increased plasma prolactin Acute dystonia such as stiff jaw, neck curvature Extrapyramidal symptoms such as decreased movement, tremor, increased salivation,... Lower blood pressure Slow heart rate Increased liver enzymes Malignant neurologic syndrome Before prescribing medication, the doctor always Weigh the benefits and effectiveness of Amisulpride more than the risk of side effects. However, some cases when taking Amisulpride can still occur unwanted effects. Therefore, when there are unusual signs after taking the drug, especially when a severe allergic reaction occurs with accompanying signs such as difficulty breathing, severe dizziness, swelling, rash or itching of the face, throat, tongue,... In this case, the patient should immediately notify the medical staff for immediate intervention.

5. Some notes when using Amisulpride drug

Some notes when using Amisulpride include:
Inform your doctor about a history of allergy to Amisulpride or any other allergies. Amisulpride may contain inactive ingredients and could cause an allergic reaction or other serious problems. Report any medications you are taking including prescription and nonprescription drugs, herbs and supplements, foods, dyes or preservatives. Amisulpride should be used with caution in patients with a history of seizures because amisulpride lowers the seizure threshold. Amisulpride should only be used for Parkinson's patients when absolutely necessary, because it will make the condition worse. When stopping the drug, it is necessary to reduce the dose gradually, not abruptly. Amisulpride may prolong the QT interval and pose a risk of severe ventricular arrhythmias such as torsades de pointes if the patient presents with pre-existing bradycardia, hypokalemia, and congenital prolongation of the QT interval. For the elderly, it is important to weigh the benefits and risks before taking the drug, because the elderly with dementia can increase the risk of death and increase the risk of stroke or ischemic attack. In addition, the elderly are prone to postural hypotension or decreased or increased body temperature in cold or hot weather. Therefore, its use is not recommended for the treatment of mild and moderate psychotic symptoms in the elderly, requiring a reduction in the starting dose and frequent monitoring during treatment. High doses can make the patient sensitive to light, so patients should avoid direct sunlight. Amisulpride should be used with caution in patients with severe respiratory disease and in patients with a history of jaundice, hematopoietic disorders or a CBC with an infection or unexplained high fever. If you forget to take a dose, take the missed dose as soon as possible. However, if it is almost time for the next dose, skip the missed dose and continue taking the medicine as scheduled. Do not arbitrarily use the drug twice the dose more than the treatment regimen. Using an overdose of Amisulpride can cause serious symptoms such as nausea, vomiting, abdominal pain, weakness,...

6. Drug interactions

Drug interactions can reduce the effect of Amisulpride, or increase the effect of unwanted effects. Tell your doctor about all other medicines you are taking including vitamins, over-the-counter medicines, prescription drugs, and herbal products. Do not stop, start, or change the dose of any medicine without your doctor's consent without your doctor's consent.
Some drugs that can interact with Amisulpride include:
Antiarrhythmic drugs such as disopyramide, quinidine, procainamide Class III antiarrhythmic drugs such as sotalol, amiodarone Levodopa Bepridil, sultopride, thioridazine, intravenous erythromycin, intravenous vincamine Vascular, pentamidine, halofantrin, sparfloxacin Some drugs when combined with Amisulpride increase the risk of torsades de pointes, such as calcium channel blockers diltiazem, verapamil, guanfacin, clonidine, digitalis, beta blockers. Dopamine agonists such as levodopa Sedatives such as haloperidol, lithium, pimozide, imipramine Drugs causing hypokalemia such as laxatives, hypokalemia, intravenous amphotericin B, tetracosatides, glucocorticoids. Central nervous system depressants such as anesthetics, analgesics, sedatives, H1 antihistamines, benzodiazepines, barbiturates,...

7. How to store Amisulpride

Store Amisulpride at room temperature, away from light and away from moisture. Do not store Amisulpride in a humid place or in the freezer. Different medicines will have different ways of storing them, so read the instructions for storing Amisulpride on the package carefully, or ask your pharmacist. Keep Amisulpride out of the reach of children and family pets. When the medicine has been damaged, it cannot be used anymore or has expired, please dispose of the medicine according to the correct procedure. Do not arbitrarily dispose of Amisulpride into an environment such as a water pipe or toilet unless requested to do so. Please consult your waste disposal company or pharmacist for advice on how to safely dispose of Amisulpride to help protect the environment. In a nutshell, Amisulpride is an effective treatment for schizophrenia, working by blocking the effects of a brain chemical that affects thinking, behavior, and feelings. However, Amisulpride can cause some unwanted effects and drug interactions, so tell your doctor what medicines you are taking to reduce the risk of side effects and increase effectiveness. for the treatment.
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