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Alodipine 5 belongs to the group of cardiovascular drugs, which are indicated for the treatment of high blood pressure and cardiovascular disease for patients. So how is Alodipine 5 used? The following article will provide information about the effects and precautions when using this drug.
1. What is Alodipine 5?
Alodipine 5 contains ingredients Atenolol 50mg, Amlodipine 5mg and excipients just enough provided by the manufacturer. The drug is prepared in the form of tablets, packed in a box of 5 blisters, each blister has 10 tablets.
Mechanism of action of the drug Alodipine 5:
Active ingredient atenolol in the drug helps lower blood pressure in people with high blood pressure by inhibiting Renin release in the paraglomerular glands, inhibiting the vasomotor center causing vasodilation, increased competition with catecholamine hormone (this hormone causes vasoconstriction and increased heart rate). Amlodipine active ingredient in the drug inhibits Ca + ions from passing through the cell membrane into the myocardium and smooth muscle of the vessel wall, thereby reducing the contractility of the arterioles, reducing the peripheral resistance, leading to a decrease in blood pressure. pressure. Besides, the active ingredient Amlodipine is effective in fighting angina by reducing cardiac afterload and dilating peripheral arterioles.
2. What are the effects of Alodipine 5?
Alodipine is indicated for treatment in the following cases:
Treatment of hypertensive patients. Treatment of patients with myocardial ischemia, angina pectoris due to fixed coronary artery stenosis (stable angina), coronary artery spasm (Prinzmetal's angina). On the other hand, Alodipine 5 is contraindicated to treat the following patients:
Hypersensitivity or history of hypersensitivity to the active ingredients or any of the ingredients in the drug's ingredients. In case the patient has bradycardia, heart failure, right ventricular failure, 2nd and 3rd degree atrioventricular block.
3. Dosage and how to use Alodipine 5
Alodipine 5 is in the form of tablets and should be taken orally. Take the medicine with cooled boiled water, swallow the tablet whole, do not break, chew or crush the tablet before taking it.
The usual therapeutic dose is 1 tablet / day. If the condition is severe, the dose can be increased to 2 tablets per day, depending on the individual response of the patient under the direction of the physician.
The above dosage is only the recommended dose, the treating doctor will depend on the condition of each patient to prescribe the appropriate dose.
4. Side effects of the drug Alodipine 5
Before prescribing, the doctor always considers the effective benefit that Alodipine 5 drug and the possible risk to the patient while taking the drug. However, some cases when using Alodipine 5 may still occur undesirable effects as follows:
Common: Heart failure, palpitations, bradycardia, atrioventricular block, chest pain, dizziness, hypotension blood pressure, fatigue, headache, dizziness, tinnitus, insomnia, depression. Uncommon: Rash, pruritus, epistaxis, night sweats, decreased libido, nausea, vomiting, diarrhea, loss of appetite. In the course of taking the drug, when the patient encounters the above undesirable effects or any symptoms, immediately notify the doctor for advice and appropriate intervention.
5. Alodipine 5 . drug interactions
To avoid interactions that occur when using a combination of different drugs, the patient should tell the treating doctor about the drugs you are using such as prescription drugs, over-the-counter drugs, dietary supplements. Functions, herbs...
The following are some drugs that are likely to interact with Alodipine 5 when used in combination as follows:
Alodipine 5 is safe to be used in combination with thiazide diuretics, blockers. beta-blockers, ACE inhibitors, nitrate derivatives and oral hypoglycemic agents. Co-administration of Alodip 5 with steroidal anti-inflammatory drugs (NSAIDs), especially Indomethacin, may reduce the antihypertensive effect of this drug by inhibiting prostaglandin synthesis in the kidney and/or sodium and fluid retention. . Concomitant use with anesthetic agents has the potential to increase the antihypertensive effect of Alodipine 5 .
6. Some notes when using Alodipine 5
Here are some notes when taking Alodipine 5 to help achieve the effectiveness of the drug as well as reduce the risk of side effects:
Use caution when using Alodipine 5 for patients with impaired liver function. Patients should not self-medicate, increase or decrease the dose if the symptoms have improved. It is necessary to consult the treating doctor and follow the treatment regimen to achieve the best results. You should consult your doctor or pharmacist before using this medicine in children. For those who drive or operate machinery, it is still possible to use the drug because it does not affect the nervous system. However, some cases of drug use occur side effects such as drowsiness, headache ... so caution should be taken. Alodipine 5 should not be used in pregnant women because the drug has the potential to cause hypoxia to the fetus. Use the drug only in this group unless the potential benefit outweighs the potential risk to the fetus. There is no evidence to determine whether Alodipine 5 is excreted in human milk. Therefore, breastfeeding should be discontinued during treatment with this medicine. The above is the important information of Alodipine 5, carefully reading the instructions before use and strictly following the doctor's instructions will help the drug achieve the desired effect and be safe for the patient.
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