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Albunorm drug has the main ingredient is Human albumin, which is prescribed by doctors to treat a number of blood sugar diseases. To ensure effective treatment and avoid unwanted side effects, patients need to strictly follow the instructions of the doctor and medical staff.
1. The main ingredient in the drug Albunorm
Albunorm medicine 20% 100ml has the main ingredient is Albumin 20g and excipients just enough. The drug is prescribed by doctors to treat patients with reduced plasma volume, severe hypoalbuminemia,...
The dosage form of Albunorm is an infusion solution.
2. Indications and contraindications of the drug Albunorm 20% 100ml
Albumin is a solution studied and prepared from human blood. The drug contains soluble proteins and electrolytes. However, Albunorm drug has been removed from coagulation factors, blood group antibodies and plasma cholinesterases. Therefore, the drug can be given to anyone.
Albumin drug has the main effect, namely:
Helps maintain colloidal osmotic pressure in plasma (from 60 - 80%). The drug works to help bind and transport endogenous and exogenous substances in the blood (including Bilirubin, Steroid hormones,...). Accordingly, infusion of 1g of Albumin into the blood can increase the circulating plasma volume by 18ml. Thereby, helping to reduce Hematocrit and blood viscosity. Albumin is distributed in the intracellular fluid and more than 60% is in the extravascular space.
2.1.Indications of Albunorm 20% 100ml Albunorm is indicated in the following cases:
Patients with reduced plasma volume Patients with severe hypoalbuminemia with reduced plasma volume, copper whole body edema. Patients with neonatal hemolytic disease need support for hyperbilirubinemia. Albunorm is an adjuvant treatment for ARDS syndrome. Albunorm is a blood thinner in cardiopulmonary bypass. 2.2.Contraindications Albunorm is contraindicated in the following cases:
Patients with hypersensitivity or history of allergy to Albumin or any of its ingredients. The patient has severe anemia. Patients with heart failure. Increase blood volume. The patient has pulmonary edema.
3. Usage - Dosage of the drug Albunorm
3.1. How to use Albunorm Albunorm is prepared in the form of an infusion solution. Accordingly, the way to use Albunorm is as follows:
Rate of infusion of Albunorm in adults: 1ml/min. The rate of infusion in children is 1⁄4 in adults. When treating shock, the rate of infusion can be increased. Albunorm should not be infused more than 250g/48 hours. If an overdose is required, plasma should be substituted. Albunorm can be administered directly intravenously or can be diluted with an isotonic solution. If used with Albunorm in large quantities, it should be warmed to room temperature or body temperature before use. 3.2.Dose of Albunorm Depending on the clinical condition of the patient, as well as the patient's drug response, the doctor will prescribe the appropriate dose of Albunorm for each person to avoid excessive volume increase. blood. Accordingly, the recommended dose of Albunorm is as follows:
Adults
Shock due to acute hypovolemia:
Initial dose for adults is: 25g Albumin (125ml Albunorm 20% 100ml). If necessary, a dose can be repeated after 15-30 minutes. When bleeding occurs, a whole blood transfusion is required. Hypoproteinemia: Maximum dose of 1 day: 2g/kg. Burns:
Infuse 25mg of Albumin (125ml Albunorm 20% 100ml) with electrolyte solutions. In case of non-emergency burns in children, infuse 6.25-12.5g Albumin (31.25-62.5ml Albunorm 20% 100ml). Children
Usual pediatric dose is 1⁄4-1⁄2 adult dose. In addition, the child's weight can be calculated from 0.6-1g/kg. Hyperbilirubinemia in neonates: Use at a dose of 1g/kg body weight before performing a blood transfusion. Note: The above dosage is for reference only. The infusion is carried out by doctors and medical staff. Therefore, patients need to follow the instructions exactly to achieve the best results.
4. Side effects of the drug Albunorm
During the use of Albunorm, patients may experience some of the following side effects:
Hot flashes Urticaria Fever Nausea However, these side effects are rare. In addition, these reactions often disappear when the infusion rate is adjusted by slowing down or stopping the infusion. In rare cases, patients may experience anaphylactoid reactions due to clotted molecules in protein preparations or to the presence of hereditary anti-protein antibodies.
5. Albunorm . drug interactions
To avoid drug interactions with Albunorm, it should be noted:
Protein hydrolysates, containing alcohol, amino acids must not be used together with Albunorm. Albumin solution contaminated with aluminum can be toxic to people with kidney failure when infusion in large quantities. Therefore, extreme caution is required.
6. Notes when using Albunorm
In the process of using Albunorm, it is necessary to pay attention to some of the following issues:
The use of Albunorm for treatment must comply with the instructions of the doctor and medical staff. Before administering Albunorm, it is necessary to disinfect the injection site, disinfect the hands of the operator to avoid infection. Check the expiry date of the drug Albunorm before giving it to the patient, if it is past the drug's expiration date, absolutely do not use it. Recall and hand over to medical staff with expertise in handling expired drugs. Before using Albunorm, it is necessary to check the packaging, the clarity of the solution. In case, the solution is cloudy, precipitates or particles are visible to the naked eye, absolutely do not use. When infusing Albunorm into the patient's body, it is necessary to monitor arterial blood pressure, central venous blood pressure to avoid excessive increase in blood volume. Once opened, the Albunorm can only be used within 4 hours. Leftovers of Albunorm must be discarded and will not be kept for future use. Albumin is safe to use in pregnant and breastfeeding women. The drug should be stored at a temperature below 30 degrees Celsius, in a cool, dry place. Avoid exposing Albunorm to direct sunlight. Store Albunorm medicine in sealed packaging, avoid freezing, impact, break, crack medicine bottles causing contamination. In summary, the drug Albunorm has the main ingredient is Human albumin, which is prescribed by doctors to treat a number of blood sugar diseases. To ensure effective treatment and avoid unwanted side effects, patients need to strictly follow the instructions of the doctor and medical staff.
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