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Albutein has albumin as the main ingredient, so it is prescribed by doctors to treat hypovolemic shock in some diseases. This is a product of the company Grifols Biologicals Inc and is a drug used in hospitals, so patients need to take it according to the instructions of doctors and medical staff.
1. What is Albutein drug?
Albutein 25 50ml is a popular drug that works to reduce shock due to volume depletion, people with kidney disease, cirrhosis, and acute liver failure.
Albutein 20 % 50ml medicine contains the main ingredients are Albumin (Human) U.S.P 10g/50ml and excipients just enough 50ml. The drug is prepared in the form of a solution for intravenous infusion.
2. Indications and contraindications of Albutein 20% 50ml
Albumin is a drug that increases blood volume and is an anti-hyperbilirubinemic drug. Albumin is a globular and highly soluble protein that produces 70-80% of the plasma colloidal pressure. Therefore, it is important in the regulation of plasma osmotic pressure.Albumin 20% has the ability to create an osmotic pressure equivalent to 4 times the osmotic pressure of plasma in the human body. Thus, it increases the plasma volume equivalent to about 2.5 times the volume of infusion in 15 minutes, if in the case of the person being infused with adequate hydration.
The addition of volume has the effect of reducing blood concentration and blood viscosity. The extent and duration of hypervolemia will depend on the initial blood volume. When treating patients with reduced blood volume, the effects of albumin infusion into the body will persist for many hours.
For patients with normal blood volume, the dilution lasts for a more limited time. Besides, Albumin is also a transport protein, binding to drugs or toxins circulating in the blood.
Albumin is distributed in the extracellular fluid. Accordingly, more than 60% are located in the extravascular area. The total amount of albumin in the human body weighing 70kg will be equivalent to 320g and has a cycle of 15-20 days, an average of about 15g a day.
2.1. Indications of the drug Albutein Albutein solution is indicated in cases where the amount of Albumin in the patient is lost a lot, for example after surgery or an accident or serious injury. Albutein solution has an auxiliary effect during hemodialysis in patients with long-term treatment or for patients with fluid overload or inability to tolerate large amounts of saline in the treatment of shock, hypothermia blood pressure . In addition, Albutein solution is also indicated for use in patients with hypovolemic shock. Besides, the drug is also indicated in patients with acute liver failure, acute kidney failure, cirrhosis of the liver ascites, acute respiratory distress syndrome (ARDS), patients who have to undergo cardiopulmonary bypass surgery.
2.2. Contraindications Albutein Albutein is contraindicated in patients who are hypersensitive to any of the ingredients. Patients with severe anemia, heart failure
3. Dosage and usage of Albutein
3.1. How to use Albutein 20% 50ml Albutein is used as an intravenous infusion. The administration of infusion should be carried out by medical staff and staff.
3.2. Dosage of Albutein In Adults
The initial infusion dose should be 100 mL. The additional injection dose depends on the medical condition. When treating patients in shock and blood volume is greatly reduced, rapid drug infusion is required to improve the pathology and restore blood volume. After about 15-30 minutes, the infusion dose can be repeated if the initial dose is not sufficient.
For patients with normal, slightly reduced blood volume, the infusion rate is adjusted to 1 mL/min.
Clinically, suitable diluents are sterile 0.9% Sodium Chloride or 5% Dextrose sterile with distilled water for injection.
In Children
The use of Albutein in young children has not been clinically evaluated. Accordingly, the dosage will vary depending on the medical condition and weight. A dose of 1/4 to 1/2 of the adult possible dose can be used, or the dose can be calculated by weight as follows: 0.6-1 g/kg body weight. The rate of infusion in young children is 1⁄4 of the rate of adults.
For children with hemolytic jaundice, the appropriate dose to bind free serum bilirubin is approximately 1 g/kg body weight during the procedure.
It should be noted: The above drug dosage is for reference only, because this is a drug prescribed and performed by staff, medical staff in the hospital, the patient should strictly follow the instructions of the doctor. avoid harm to health.
4. Possible side effects when using Albutein
The use of Albutein can cause some unwanted side effects.
Chills, Cold spines Nausea Tachycardia, Low blood pressure Shortness of breath Rash Skin rash Pulmonary edema In addition to the above side effects, during the infusion of Albutein solution, if the patient has any symptoms, need to immediately report to the doctor or medical staff so that they can be treated in a timely manner to avoid affecting health.
5. Albutein drug interactions
To avoid possible drug interactions, care should be taken not to use the same infusion line with hydrolyzed protein solutions or alcohol as it may cause precipitation.
6. Notes when using Albutein
During the use of Albutein, the patient should pay attention to the following:
Patients with low cardiac reserve: If dilution is required, use 0.9% NaCl or 5% Dextrose but do not use water. because it increases the risk of acute hemolysis and acute renal failure. Albutein infusion at a moderate rate, avoid causing pulmonary edema. Can be used in combination with Dextrose and Saline. Pregnant and lactating women: Only use Albutein when prescribed by a doctor or medical staff. Store Albutein in a cool, dry place, the temperature is below 30 degrees Celsius. Avoid exposing the medicine to direct sunlight. Do not leave Albutein near any equipment that can generate heat.
Albutein has albumin as the main ingredient, so it is prescribed by doctors to treat hypovolemic shock in some diseases. This is a product of the company Grifols Biologicals Inc and is a drug used in hospitals, so patients need to take it according to the instructions of doctors and medical staff. From there, avoid causing side effects and dangerous drug interactions.
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