Uses of Agiroxi 50

This is an automatically translated article.


Agiroxi 50 is a group of drugs that treat parasites, infections, viruses, and fungi with active ingredients. Each 1.5g pack contains Roxithromycin 50mg. Drugs manufactured by the branch of Agimexpharm pharmaceutical joint stock company - Agimexpharm pharmaceutical factory circulated in Vietnam and registered with the registration number VD-23487-15.

1. Uses of agiroxi 50


Each type of pharmaceutical product is designed to treat a specific disease or condition. Therefore, only use Agiroxi 50 to treat the conditions or conditions specified in the instructions for use. Although Agiroxi 50 may have some other effects that are not listed on the approved label, you should only use this medicine to treat certain other conditions when directed by your doctor.
Indications:
Infections caused by strains determined to be sensitive to antibiotics, mainly in:
Upper respiratory tract infections: pharyngitis, tonsillitis, sinusitis. Lower respiratory tract infections: pneumonia, bronchitis, chronic bronchial disease superinfection, atypical pneumonia. Skin and soft tissue infections. Non-gonococcal genital tract infections: urethritis, cervicitis-vaginitis. Oral infection. Contraindications:
Hypersensitivity to macrolides. Concomitant use with ergot alkaloids (ergotamine and dihydroergotamine).

2. Dosage and how to use Agiroxi 50


Usage:
Each drug, pharmaceutical product is produced in different forms and has different usage according to the route of administration. The usual routes of drug administration by drug form are: oral drugs, injections, external drugs and suppositories. Carefully read the instructions on how to use Agiroxi 50 above from the instructions for use of the drug, do not arbitrarily use the drug according to other routes not stated in the instruction sheet of Agiroxi 50. Dosage:
Take the medicine before meals , divided into 2 times/day.
Adults: 300mg/day: 1 Agiroxi 150mg tablet morning and evening. Children: 5-8mg/kg/day, divided into 2 times. In children, treatment is maximum for 10 days. Dosage of Agiroxi 50 for adults:
Dosing regulations are usually intended to guide adults following oral administration. Dosage for other routes is specified in the leaflet. Do not change the dose on your own without consulting your doctor or pharmacist. Dosage of Agiroxi 50 for children:
Differences between children and adults such as pharmacokinetics, pharmacodynamics, side effects... especially children are not allowed to be tested. clinical practice before granting marketing authorization for a new drug. Therefore, using this drug for children should be very careful even with drugs that have not been warned.
Overdose, missed dose, emergency:
In case of emergency or overdose with dangerous manifestations, call 911 Emergency Center or go to the nearest local Health Facility. Relatives need to provide the doctor with the prescription they are taking, the medicines they are taking, including prescription and non-prescription drugs. If you miss a dose while you are taking it, take it as soon as possible (usually it can be taken 1-2 hours before the time ordered by the doctor). However, if the time is close to the time. next dose, skip the missed dose and take your next dose at the scheduled time. Be careful not to double the prescribed dose.

3. Note before taking Agiroxi 50


When macrolide antibiotics are used in combination with vasoconstrictor alkaloids of ergot, vasoconstriction of the extremities which can lead to necrosis has been reported. Before prescribing Roxithromycin, make sure the patient is not taking these alkaloids. Caution in severe hepatic impairment: reduce dose by half if Roxithromycin is necessary. In case of renal failure, the elderly: no need to adjust the dose. Be wary of subjects driving vehicles and using machines about the risk of dizziness caused by the drug. Pregnancy: No teratogenic effects in animals. In humans, safety for the fetus has not been established. Lactation: Weakly excreted in breast milk. Do not take the drug while breastfeeding or stopping breastfeeding. Many drugs have not yet fully determined the effects of the drug during this period, so mothers need to carefully read the instructions for use and consult with doctors and pharmacists before deciding to use the drug.

4. Side effects of the drug Agiroxi 50


Gastrointestinal manifestations: nausea, vomiting, stomach pain, diarrhea. Skin allergies: rash, urticaria, angioedema. At high doses, transaminase levels are temporarily elevated, rarely causing cholestatic hepatitis. Feeling dizzy, headache, paresthesia. Rarely, severe hypersensitivity reactions (Quincke's edema, anaphylactoid reactions). Other side effects:
It should be noted that the above is not a complete list of all side effects of Agiroxi 50. In the process of use, other side effects may occur that have not yet manifested or have not been shown. studied. If there are any other side effects of Agiroxi 50 not specified in the instructions for use, consult your doctor or pharmacist.

5. Drug interactions


When using two or more drugs at the same time, it is easy to have drug interactions leading to antagonism or synergism.
Drug interaction Agiroxi 50 with other drugs
Contraindications to combination: ergot alkaloids (ergotamine, dihydroergotamine) cause vasoconstriction. Should not combine: terfenadine, astemizole, cisapride, pimozide. With caution in combination: vitamin K antagonists, disopyramide, digoxine and other glycosides. Note when combining: midazolam, theophylline, cyclosporine A. Interaction Agiroxi 50 with food and drinks
When using the drug with foods or alcohol, beer, tobacco... due to foods , that drink contains other active ingredients, so it can have an antagonism or synergistic effect with the drug. Read the instructions for use carefully or consult your doctor or pharmacist about taking Agiroxi 50 with food, alcohol and tobacco. Pharmacodynamics
Roxithromycin is a semi-synthetic antibiotic of the macrolide family.
Pharmacokinetics
Roxithromycin penetrates well into the cells and cavities of the body. Especially, the drug reaches high concentrations in the lungs, tonsils, sinuses, prostate, and uterus. Roxithromycin does not cross the blood-brain barrier. Since roxithromycin is eliminated primarily by hepatic metabolism and its metabolites are excreted in the bile and faeces, normal doses can be used in patients with renal insufficiency. Drug storage
Store below 25 degrees Celsius, in a tightly closed container. Keep Agiroxi 50 out of the reach of children and away from pets. Before using Agiroxi 50, it is necessary to double-check the expiry date indicated on the product packaging, especially with medicines stored at home.

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