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Afedox drug with the main ingredient is Cefadroxil, used to treat bacterial infections such as: urinary tract infections, sore throats, respiratory infections, skin and soft tissue infections,... Here are some information information to help patients learn and use drugs safely and effectively.
1. What is Afedox?
Afedox is a drug belonging to the group of drugs used to treat parasites, infections, viruses and fungi. Afedox is manufactured at Nhan Hoa Pharmaceutical Trading Co., Ltd. Prepared in the form of capsules - 500mg and packed in boxes of 10 blisters x 10 tablets.Afedox medicine has the main ingredient Cefadroxil and other excipients just enough for 1 capsule.
2. What are the uses of Afedox?
Afedox is used to treat patients in the following cases:
Urinary tract infections. Infections of the skin and subcutaneous soft tissues. Tonsillitis and pharyngitis. Respiratory tract infections such as: pneumonia, acute exacerbation of chronic bronchitis, bronchiectasis.
3. Dosage - How to take Afedox?
3.1. How to take the drug Afedox is produced in the form of capsules and is tolerated and in the body orally in combination with cooled boiled water or purified water and swallowed whole.
3.2. Dosage Dosage of Afedox drug depends on each subject and the course of the disease, there will be an appropriate dose. Below is a reference dose of Afedox as follows:
Patients can use the drug once or divided into 2 times a day. For adults: The dose is 1g - 2g of Cefadroxil/day. For children: The dose is 25-50mg Cefadroxil/kg/day. In case of patients with renal failure: ClCr clearance 25 - 30mL/min: The interval between doses is 12 hours. ClCr clearance 10 - 25mL/min: The interval between doses is 24 hours. ClCr clearance 0 - 10mL/min: The interval between doses is 36 hours.
4. What to do in case of overdose of Afedox?
In the case of an overdose of Cefadroxil, the patient will have the following symptoms:
Nausea and vomiting. Epigastric pain. Go diarrhea. Severe convulsions may occur. Management:
Treatment includes keeping airway open, serum electrolytes and blood gas testing. If convulsions occur, Cefadroxil should be discontinued immediately. Anticonvulsants may be used. When there is any phenomenon of drug overdose, the patient also needs to notify the doctor for examination or go to the nearest medical facility for timely intervention to avoid endangering health.
5. In which cases is Afedox not used?
Afedox is not used for patients with hypersensitivity or history of allergy to Cephalosporins and excipients in the drug.
6. Side effects of the drug Afedox
When using Afedox to treat patients, there may be some unwanted effects as follows:
Uncommon: Hypersensitivity reactions such as: Rash, urticaria have been reported. Rare: Usually occurs in the digestive system such as: Nausea, vomiting. Diarrhea. Other side effects: Vaginitis, genital itching and transient neutropenia. Usually, all of these side effects will subside and go away when the patient stops taking Afedox. When one of the above side effects occurs, the patient should notify the doctor or pharmacist for timely remedy.
7. Precautions when using Afedox
Patients who decide to treat their disease with Afedox should pay attention to a few things:
There have been clinical and subclinical reports of partial cross-allergies between Cephalosporins and Penicillins. There have been cases of allergic reactions to both drugs, causing shock and death after injection). Therefore, Afedox should not be used in patients who are hypersensitive to penicillin. Cephalosporin antibiotics must be used with caution in patients with a history of penicillin allergy. Caution should be exercised when using Afedox in patients with a history of gastrointestinal disease, especially colitis. Broad-spectrum antibiotic therapy alters the normal bacteria of the colon and may cause Clostridia to overproduce. Cefadroxil should be used with caution in patients with severe renal dysfunction or severe renal failure with a creatinine clearance (ClCr) < 50 ml/min/1.73 m2. Long-term use of Cefadroxil in patients can cause overproduction of non-susceptible organisms. Patients should be closely monitored. If superinfection occurs during treatment with the drug, appropriate measures should be taken. Afedox should not be used in pregnancy: Studies in rats at doses up to 11 times that of humans showed no evidence of harmful effects on conception or on the fetus. due to the ingredient Cefadroxil. Despite this, there are no adequate and well-controlled clinical trials in pregnant women. In case it is necessary to treat with Afedox medicine for pregnant women, it is necessary to consult a doctor. Afedox should not be used in lactating women because it is excreted in breast milk and is transiently neutral. In case it is necessary to treat with Cefadroxil, it must be used with caution, under the supervision and guidance of a doctor. Afedox is prescribed by a doctor, and patients should not self-medicate without a prescription. Above is the entire information about Afedox drug, patients need to carefully read the instructions for use, consult a doctor / pharmacist before using. Note, Afedox is a prescription drug, patients absolutely cannot buy and treat at home because they may experience unwanted side effects.
