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Aceralgin 400mg is a medicine with active ingredient Aciclovir 400mg which is usually indicated for cases of Herpes simplex infection. To use the drug to achieve the best results and ensure safety, users need to know the information about the uses, indications and notes when using the drug below.1. What is Aceralgin 400mg?
Aceralgin 400mg is a drug belonging to the group of anti-parasitic, anti-bacterial, anti-viral, anti-fungal drugs with the main active ingredient Aciclovir 400mg. The drug is usually indicated for the treatment of Herpes simplex infection, prevention of genital herpes re-infection ...Aceralgin 400mg drug is prepared in the form of tablets, packaged in a box of 1 blister x 10 tablets.
2. What are the medicinal uses of Aceralgin 400mg?
2.1 What does Aceralgin 400mg do? Active ingredient Acyclovir is a selective agent on cells infected with Herpes simplex virus (HSV). To be effective, acyclovir must be phosphorylated to the active form acyclovir triphosphate. Acyclovir triphosphate inhibits DNA synthesis and viral replication without affecting normal cellular metabolism.
The effect of acyclovir is strongest on Herpes simplex virus type 1 (HSV - 1) and worse on HSV - 2, Varicella zoster virus (VZV), the weakest effect on acyclovir is on cytomegalovirus (CMV).
Acyclovir has good effect in the treatment of severe encephalitis caused by HSV-1 virus, can reduce the mortality rate from 70% to 20%. The milder form of encephalitis-meningitis caused by HSV-2 can also be treated with acyclovir.
In critically ill patients requiring intravenous infusion of acyclovir such as HSV infection in immunocompromised individuals, organ transplant recipients, AIDS, blood malignancies, oral or genital herpes, neonatal herpes , severe herpes keratitis.
2.2 Indications: With the action of the active ingredient acyclovir, Aceralgin 400mg is usually indicated in the following cases:
Treatment of Herpes simplex virus (HSV) in the skin and mucous membranes including the initial infection and recurrent genital herpes (except neonatal HSV infection and HSV infection in severely immunocompromised children). Prevention of recurrence of Herpes simplex infection in immunocompetent patients. Prevention of herpes simplex virus infection in immunocompromised patients. Treatment of Herpes zoster (shingles) and Varicella virus (chickenpox) 2.3 Contraindications: Aceralgin 400mg drug containing acyclovir is contraindicated in some of the following cases:
Hypersensitivity to acyclovir component or excipients in the drug. People with kidney failure or anuria. Women who are pregnant or breastfeeding.
3. How to use – Dosage of Aceralgin 400mg
Uses of Aceralgin 400mg will be maximized if the patient takes the drug correctly and at the right dose prescribed by the doctor. Or refer to the instructions for use and dosage below:
How to use:
Aceralgin 400mg is made in the form of tablets, so it should be taken orally with plenty of water. To avoid stomach irritation, the drug can be taken after meals.
Should take medicine with cooled boiled water or purified filtered water. Do not take the drug with alcohol, beer, coffee, tea, soft drinks, fruit juice... can reduce the effect of the drug.
The tablet has a line in the middle of the tablet, so it can be divided into two according to the line to match the dose of 200mg.
Dosage:
Adults infected with Herpes simplex: Take 200mg x 5 times/day x 5 days. Prevention of reinfection of genital herpes and severe forms: Oral 200mg x 4 times/day, or 200mg x 3 times/day or 200mg x 2 times/day. Shingles: Take 800mg x 5 times/day. Prevention of re-infection: Take 400mg x 4 times/day. Immunosuppression: 200mg x 4 times/day. Severe immunodeficiency: 400mg x 4 times/day. Children over 2 years old take the adult dose, children under 2 years old take half the adult dose. Patients with renal impairment reduce the dose. Note: The above dosage is for reference only, and the specific dose may be changed according to the medical condition of each person. Consult a qualified physician for advice on the best dosage and administration of the drug.
4. Aceralgin 400mg . side effects
Aceralgin 400mg medicine can cause some side effects such as:
Common side effects: Headache, dizziness, nausea, vomiting, diarrhea, abdominal pain, itching, rash, light allergy , tired. Uncommon side effects: diffuse alopecia, urticaria, Rare side effects: anaphylaxis, dyspnea, reversible increase in bilirubin and liver enzymes, angioedema, slight increase in blood urea and creatinine. Very rare side effects: acute renal failure, hepatitis, jaundice, agitation, confusion, hallucinations, psychotic symptoms, somnolence, tremor, dysarthria, convulsions, ataxia, kissing passionate about. In the process of using the drug, if you experience the above side effects or other unusual signs, you should immediately notify the treating doctor for advice and appropriate treatment.
5. Aceralgin 400mg drug interactions
Aciclovir is eliminated primarily by the kidneys through active tubular secretion. Therefore, co-administration of any drug that competes with this mechanism may increase plasma concentrations of acyclovir.
Probenecid and cimetidine increase the AUC of aciclovir by this mechanism and decrease the renal creatinine clearance of aciclovir.
To avoid drug interactions that affect the effectiveness of Aceralgin 400mg and other drugs being used by the patient, please inform the treating doctor about the drugs you are taking for appropriate advice, indications and prescriptions. best.
6. Notes and cautions Aceralgin 400mg
To ensure safety and help the drug Abab 325mg promote its full use, users should note and be cautious of some of the following issues:
Use the drug according to the dosage prescribed by the doctor or according to the manufacturer's instructions. . Do not arbitrarily increase or decrease the dose or cancel the treatment course will affect the treatment results. For the use of Aceralgin 400mg solution, do not apply to the eyes, mouth and vagina, be careful when applying in the posterior area. genitals and genitals. For subjects who are elderly or have severe renal impairment, the dose of acyclovir should be reduced. Pay attention to maintain enough water for patients taking high dose Aceralgin 400mg to treat Herpes Zoster to avoid affecting the kidneys. Aceralgin contains lactose, so it is not recommended for patients with hereditary galactose intolerance, those with Lapp lactase deficiency or those with poor glucose-galactose malabsorption. Acyclovir should not be taken by mouth for pregnant or lactating women, as it may affect the fetus and breast milk. There is no evidence of the effect of the drug on the ability to drive or operate machinery. However, if you are operating a generator or driving a car, you should not use the drug because it can cause dizziness and hallucinations.
7. Handling missed dose, overdose Aceralgin 400mg
Missed dose: If you miss a dose, take it as soon as you remember, but if it is almost time for the next dose, skip the missed dose and take the next dose as scheduled. Absolutely do not take a double dose, double the dose to make up for the missed dose to avoid overdose.
Overdose: When acyclovir overdose, patients often have symptoms on the gastrointestinal tract such as nausea, vomiting and on the nervous system headache, convulsions... When experiencing an overdose, the patient should be Careful and thorough monitoring for supportive and symptomatic treatment.
In case of danger and emergency, it is necessary to take the patient to a medical facility to be examined and the doctors will take timely and effective measures.
Above is all the information about Aceralgin 400mg that people need to know before using the drug to ensure the safest use and the best and fastest treatment effect.
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