Treatment of stage 3 vú breast cancer

This is an automatically translated article.

Stage 3 breast cancer means the cancer has spread outside the main tumor in the breast. It may have invaded the lymph nodes but has not spread to nearby organs.

1. What is stage 3 breast cancer?

In stage 3, breast cancer has spread outside the breast and into nearby lymph nodes, so it is more difficult to treat than earlier stage breast cancer, although this depends on some factors. certain factors.
With aggressive treatment, stage 3 breast cancer can be cured, but the risk of the cancer coming back after treatment is quite high. Doctors divide stage 3 breast cancer into more specific types, including 3A, 3B, and 3C. The stage 3 breast cancer classification will help doctors choose for the patient the treatment that is most likely to work.
1.1 Stage 3A No tumor found in breast or breast tumor of any size. At this point, cancer has been found in 4 to 9 nearby lymph nodes. The tumor was larger than 5cm and small clusters of cancer cells were found in nearby lymph nodes. The tumor was larger than 5 centimeters and cancer was also found in three nearby lymph nodes near the breastbone or under the arm. 1.2 Stage 3B In stage 3B breast cancer, your doctor can find a lump of any size. Cancer cells have now spread into the chest wall, the skin of the breast, nine nearby lymph nodes, and the lymph nodes near the breastbone.
1.3 Stage 3C Breast cancer has invaded the chest wall/skin of the breast leading to symptoms of inflammation and skin ulcers. In addition, at stage 3C, breast cancer also has the following features:
Cancer has invaded ten or more axillary lymph nodes Cancer has invaded into the lymph nodes up to the collarbone Cancer has invaded into the lymph nodes under the arm and near the breastbone.

2. What is the survival rate for stage 3 breast cancer?

According to the American Cancer Society, the estimated 5-year survival rate for patients with stage 3 breast cancer is 86%, which is 86 out of every 100 people with breast cancer at this stage. live 5 years.
Meanwhile, the 5-year relative survival rate for stage 0 breast cancer is 100%, stage 1 & 2 is 99%, and stage 4 drops to 27%.

3. What is the life expectancy of people with stage 3 breast cancer?

The life expectancy of people with stage 3 breast cancer can now be significantly improved thanks to progressive treatments, healthcare experts say.
Life expectancy of a patient with stage 3 breast cancer will depend on several factors:
Age Overall health Response to treatment Size of the tumor. Ideally, patients should talk to their doctors about the potential benefits of stage 3 breast cancer treatments on their life expectancy.

4. Treatment options for stage 3 . breast cancer

Stage 3 breast cancer has spread beyond the breast and invaded nearby lymph nodes. In general, treating stage 3 breast cancer requires a combination of many different treatments to be most effective.
4.1 Chemotherapy Chemotherapy is a common treatment for stage 3 breast cancer. Sometimes, patients need chemotherapy before surgery to shrink tumors and make them easier to remove. In addition, chemotherapy also helps destroy the remaining breast cancer cells after surgery.
In cases where surgery for stage 3 breast cancer is not an appropriate option, chemotherapy may become the mainstay of treatment. Chemotherapy for each stage 3 breast cancer patient can be different, such as oral/intravenous drugs and other fluids.
4.2 Surgery Surgery for stage 3 breast cancer usually involves surgical removal of the tumor and some tissue around the breast. In certain cases, your doctor may recommend a complete mastectomy and lymph node removal.
After surgery for stage 3 breast cancer, patients can choose to have breast reconstruction surgery after cancer treatment.
4.3 Radiation Therapy Radiation therapy is often recommended for women with stage 3 breast cancer after surgery. This treatment helps destroy cancer cells that are left behind after surgery.
4.4 Hormone therapy Hormone therapy can be effective in treating women with hormone-receptor-sensitive breast cancer. Medications commonly used in hormone therapy to treat stage 3 breast cancer include:
Letrozole (Femara) Exemestane (Aromasin) Tamoxifen Toremifene (Fareston) Fulvestrant (Faslodex) Women with stage 3 breast cancer If you're not postmenopausal, you can have your ovaries removed or use medications to block the production of hormones that stimulate cancer growth.

4.5 Targeted therapy Targeted therapy, also known as targeted therapy – is a newer treatment for stage 3 breast cancer. According to experts, about 20% of women with breast cancer have HER2 levels above the normal range, which causes breast cancer cells to spread rapidly in the body.
People diagnosed with HER2-positive breast cancer can be treated with fam-trastuzumab deruxtecan-nxki (Enhertu), ado-trastuzumab emtansine (Kadcyla), lapatinib (Tykerb), neratinib (Nerlynx), margetuximab (Margenza), trastuzumab (Herceptin), and pertuzumab (Perjeta). In addition, CDK 4/6 inhibitors are sometimes used in postmenopausal women with advanced breast cancer. These drugs help block the HER2 protein that stimulates breast cancer to grow and make chemotherapy more effective.
Women who are HER2 negative but have BRCA mutation stage 3 breast cancer can be treated with a PARP inhibitor, such as talazoparib (Talzenna) or olaparib (Lynparza). HER2-negative patients with metastatic breast cancer due to PIK3CA mutations may be treated with a PIK3 inhibitor such as alpelisib (Piqray) along with fulvestrant.
Treatment for stage 3 breast cancer may include immunotherapy drugs, which help stimulate the body's immune system to destroy cancer-causing cells. Immunosuppressants such as atezolizumab (Tecentriq) may be used together with the chemotherapy drug paclitzxel (Abraxane).
Breast cancer is a common cancer in women, it is estimated that every year around the world, many women die from this disease. However, if the disease is detected early, the prognosis for treatment is very high, even if the disease is completely cured and does not recur. Therefore, breast cancer screening is essential, especially for those at high risk of breast cancer.
Currently, Vinmec International General Hospital has been implementing a Breast Cancer Screening Package for women of different ages. At Vinmec, there is a full range of necessary medical equipment, a system of modern medical machines to perform methods of examination, diagnosis, testing, imaging, and treatment of breast cancer at many stages. . Accordingly, the breast cancer examination and treatment process at Vinmec is carried out by a team of highly qualified doctors and nurses who have undergone training and are technically certified, able to handle quickly and effectively. . Therefore, when using Vinmec's breast cancer screening and early detection package, customers can detect cancer even when there are no symptoms.

Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.

References: Healthline, Webmd, Cancer