This is an automatically translated article.
The article was professionally consulted with Specialist Doctor I Nguyen Thi My Linh - Department of Pediatrics - Neonatology - Vinmec Danang International General Hospital.Sepsis is a dangerous condition with a high risk of death due to septic shock and multiple organ failure. Sepsis cannot go away on its own if left untreated. The treatment of sepsis in children needs to combine the treatment of the cause and the complications to minimize the health risks for the child.
1. Blood sugar infections in children
Children's immune system is not fully developed, the ability to fight off pathogens is low, leading to a high risk of infection.Sepsis is a condition in which the presence of bacteria in the blood is accompanied by clinical manifestations of infection. The source of infection can be from many different locations on the body such as: skin, muscle, respiratory system, urinary system, digestive system... Identifying the initial infection site helps orient the use of antibiotics. highly effective.
Sepsis has an extremely complicated disease process, with a high mortality rate. Sepsis causes a series of changes in the body that damage organs such as the liver and kidneys and make the patient's health decline rapidly.
Sepsis causes many life-threatening complications for children such as:
Respiratory failure Decreased clotting factors Multi-organ failure Septic shock: A serious and common complication. Sepsis in children can be completely cured, reducing the risk of death if detected in time.
Bệnh nhiễm trùng máu có chữa khỏi được không là thắc mắc của nhiều người
2. How to treat blood infection
2.1 Principles of treatment Treat the cause: Kill the bacteria causing sepsis, to determine the cause of the disease should be based on the laboratory results. Treatment of complications caused by sepsis. Improving resistance 2.2 Treating the cause of the disease The cause of the disease is a bacterial infection, so treatment is mainly to kill bacteria with antibiotics.Principles of antibiotic use
Use of antibiotics according to the results of the antibiogram. High-dose antibiotics Use parenteral antibiotics, preferably intravenously, for the first few days. Need to combine antibiotics (with bacteria resistant to antibiotics and unknown pathogens). The duration of antibiotic use is not less than 2 weeks, depending on the specific case, it may be necessary to use monthly for a month. Combination of antibiotics when: To treat the siege when the pathogen has not been isolated The pathogen is resistant to antibiotics or the infection is caused by many pathogens Prevent and slow the emergence of resistant strains Increase the ability of antibiotics to inhibit and kill bacteria. Treatment regimens for sepsis are applied:
Gram (+) bacteremia often results Cases of first-generation Cephalosporin antibiotics with Quinolones or aminoglycosides Bacteremia caused by Gram-negative bacteria, often combined with third-generation Cephalosporin antibiotics with Quinolones or aminoglycosides, nosocomial infections are usually caused by bacteria multi-resistance using strong, broad-spectrum antibiotics before the results of the antibiogram are available. The antibiotic of choice is Imipenem/meropenem or Quinolone or Ticarcillin in combination with clavulanic acid. or Cefoperazone-Sulbactam ± Amikacin. After 10-14 days of antibiotic treatment, re-evaluate clinical and subclinical results to select an appropriate antibiotic.
Điều trị nguyên nhân là cách điều trị nhiễm trùng máu phổ biến
Restore circulating volume, correct water and electrolyte disturbances, detoxification with solutions of Dextrose, Ringer lactate. Anti-metabolic acidosis: often a consequence of shock, septic shock should be treated aggressively to avoid prolonged shock. In case of severe acidosis, it is necessary to correct with Bicarbonate. Coagulation disorders: Transfusion of platelets and frozen plasma, cryoprecipitate. Cardiovascular support, respiratory resuscitation, cardiovascular. Continuous hemodialysis: When acute renal failure with hemodynamic instability, multi-organ failure. Dialysis in addition to treating acute renal failure dialysis also helps to remove Cytokines and intermediate chemicals. 2.4 Remove infected foci If an infection is detected, it should be thoroughly resolved such as:
Surgical removal of the infection. Incision to drain the abscess Discard the causes of infection such as catheters, drainage tubes... 2.5 Improve resistance Strengthen resistance with blood transfusion, protein, vitamins... Diet Drink variety, increase protein, green vegetables and fruits.
3. Prevention of bacteremia
Children are fully vaccinated against vaccines. Babies should be exclusively breastfed for the first 6 months. Aseptic work in the Hospital is to limit the risk of hospital infections, or when doing surgery, procedures... Thoroughly treat diseases with pus and abscesses. Do not squeeze, extract the pimples early. Use antibiotics early, in full doses, effective in diseases that can turn to sepsis (diseases caused by staphylococcus, streptococci, pneumococcal bacteria, intestinal bacteria...) Use of immunosuppressive drugs required Strict regimen and used together with drugs to increase the patient's resistance. Sepsis in children is a life-threatening condition, but it can be completely cured if diagnosed early and treated promptly.Vinmec International General Hospital is one of the hospitals that not only ensures professional quality with a team of leading medical doctors, modern equipment and technology, but also stands out for its examination and consultation services. comprehensive and professional medical consultation and treatment; civilized, polite, safe and sterile medical examination and treatment space. Customers when choosing to perform tests here can be completely assured of the accuracy of test results.
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