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Amcefal 2g drug is a drug to treat respiratory infections, infectious dermatitis and skin structure, bacteremia... On the market today there is a lot of information about Amcefal drug products, but it is still incomplete. enough. To better understand what Amcefal 2g is, let's learn more in the article below.
1. What is Amcefal 2g?
Amcefal 2g with Cefamandol ingredient helps users to solve problems such as respiratory and skin infections effectively and with high safety. Amcefal 2g has been tested and put into use in many hospitals across the country.
1.1 Basic information Main active ingredient: Cefamandol Active ingredient classification: Second generation cephalosporin antibiotic. Trade name: Amcefal Cefamandol - 2g Excipients just enough. 1.2 Dosage form: Powder for injection Product packaging: Box of 1 vial Origin: Vietnam Cefamandol is a semi-synthetic broad-spectrum cephalosporin antibiotic. As with existing 2nd generation cephalosporins, cefamandol has similar or lesser activity against Gram-positive cocci, but is more potent against Gram-negative bacteria in vitro, when compared with first-generation cephalosporins. Cefamandol has a narrower spectrum of activity against Gram-negative bacteria than third-generation cephalosporins. The bactericidal effect of cefamandol is due to inhibition of bacterial cell wall synthesis. Cefamandol is generally active against the following microorganisms in vitro and in clinical infections.
2. What are the uses of Amcefal?
Each type of pharmaceutical product is primarily used to treat a specific disease or condition. That's why, use Amcefal only to treat the conditions or conditions specified in the instructions for use.
Treatment of lower respiratory tract infections (including pneumonia) caused by Haemophilus influenzae, klebsiella, Proteus mirabilis, Staphylococcus aureus, Streptococcus pneumoniae, urinary tract infections; Peritonitis; Skin and skin structure infections; Septicemia and Musculoskeletal Infections. Treatment of mixed aerobic and anaerobic infections in the treatment of gynecological, lower respiratory tract, skin and skin structures. Prophylaxis of infection before and after surgery.
3. Side effects of Amcefal 2g
Common, ADR > 1/100
Cardiovascular: Causes thrombophlebitis when injected into peripheral veins. Systemic: Pain and inflammation reactions to intramuscular injection and hypersensitivity reactions. Uncommon, 1/100 >ADR>1/1000
Central nervous system neurotoxicity. Cephalosporin allergy (anaphylaxis) Blood: Immune hemolytic anemia reduces neutrophils to agranulocytosis, hemolysis and clinical bleeding due to disorders of coagulation and platelet function. Hepatic: Slight increase in serum alkaline phosphatase and transaminases. Kidney: Acute interstitial nephritis. Gastrointestinal: Nausea, vomiting, diarrhea. Long-term use can cause pseudomembranous colitis. Renal: Renal failure and especially impaired renal function during treatment. Rarely, ADR<1/1000
Gastrointestinal: Nausea, vomiting, diarrhea. Long-term use may cause pseudomembranous colitis. Renal: Renal failure, especially impaired renal function during treatment.
4. How to use Amcefal 2g effectively?
The dose of Cefamandol nafat will be calculated according to the dose of Cefamandol base
Adults:
Deep intramuscular injection, or slow intravenous injection (from 3 to 5 minutes) or intermittent or continuous infusion of 0.5-2g, 4-8 hours /time, depending on the severity of the disease or mild
Children:
From 50-100mg/kg/day divided into several times: for severe disease, use a maximum dose of 150mg/kg body weight/day
Prophylactic surgery for adults : 1 - 2 g injected 0.5 - 1 hour before surgery, 1-2 g after surgery every 6 hours x 1-2 days. Renal impairment: adjust dose according to ClCr.
Usage:
Intramuscular: Each gram of cefamandol will be dissolved in 3ml of distilled water for injection or 0.9% NaCl solution. Shake to dissolve completely. Inject immediately after reconstitution.
Intravenous injection: Each gram of cefamandol is dissolved in 10ml of distilled water for injection; 5% dextrose injection solution or 0.9% NaCl injection solution. Shake to dissolve completely. Inject immediately after reconstitution and inject slowly into the vein for 3-5 minutes.
What to do when you overdose?
High doses can cause convulsions and other signs of central nervous system toxicity. High doses can also cause pseudomembranous colitis. The drug must be stopped and the patient must be treated immediately. In case of drug overdose that requires emergency care, family members need to bring the prescription/bottle of the drug the victim has taken. In addition, family members also need to know the height and weight of the victim to notify the doctor.
What to do if a dose is missed?
It is still best to take the medicine on time when the doctor prescribes it. Taking the medicine at the right time will also ensure the best effect of the medicine. Usually can be taken 1 to 2 hours from the time ordered by the doctor, should not make up when the time is too far for the next dose. If a dose is forgotten, it should be taken as soon as the patient remembers. If you miss a dose of Amcefal for too long and it is almost time for your next dose, skip the missed dose. Do not use 2 doses of Amcefal at the same time to make up for a missed dose.
5. Precautions, warnings and precautions when taking Amcefal
5.1 Notes before taking Amcefal 2g Use the drug exactly as prescribed by the doctor. Do not use the medicine if you are allergic to any of its ingredients or have a warning from your doctor or pharmacist. Use with caution in children, pregnant and lactating women or operating machinery.
5.2 Precautions to use Amcefal during pregnancy Before using the drug, always consult your doctor or pharmacist to weigh the benefits and risks of taking the drug while pregnant
Look up classification drugs used in pregnancy by the US Food and Drug Administration (FDA) below:
A = No risk;
B = No risk in some studies
C = Possible risk;
D = There is evidence with risk;
X = Contraindications;
N = Still unknown.
5.3 Precautions to use Amcefal during lactation General note during lactation, the drug can be passed to the baby through breastfeeding. It is best not to or limit the use of the drug during breastfeeding. Many drugs have not yet fully determined the effects of drugs during this period, so mothers need to carefully read the instructions for use and consult with your doctor and pharmacist before you decide to take the drug.
5.4 Notes on the use of Amcefal in the elderly Use caution when using the drug with the elderly because the sensitivity to the drug in this subject may be greater than that of normal adults.
6. Preservation of Amcefal
Remember that each medicine may have different storage methods. Therefore, carefully read the storage instructions on the packaging, or ask your pharmacist.
Store Amcefal 2g in a cool, dry place. The temperature should not exceed 30°C. Avoid direct sun exposure. Keep out of reach of children and pets. Above is important information about Amcefal. Using the correct dose and instructions will bring better treatment results.
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