The process of producing blood and blood products for blood replacement

This is an automatically translated article.

Blood products are produced on strict procedures and are tested for blood grouping and blood quality before being put into the patient's blood transfusion. This helps to minimize the risk of complications occurring during blood transfusion.

1. Redefining the blood group of blood products about to be put into production


Blood has been collected mainly through volunteers through the lifesaving blood donation program. Before receiving donated blood, the organizers have carried out blood grouping tests and excluded a number of infectious diseases that are not allowed for blood transfusion. After that, the blood is transferred to hematology centers and the blood group is regrouped again before producing blood products and using it to change blood for the patient.

Xét nghiệm nhóm máu trước khi sử dụng
Xét nghiệm nhóm máu trước khi sử dụng

2. AB plasma thawing


AB plasma is the plasma of blood group O, without A antigens, B antigens on the surface of red blood cells and both A and B antibodies in the plasma.
Fresh frozen plasma is plasma separated from whole blood, frozen within 6 hours of collection and stored at -18°C. One unit of fresh frozen plasma containing 200ml is equivalent to contains 1 unit of clotting factor/ml and 1-2 mg of fibrinogen/ml.
AB plasma thawing is the process of bringing plasma from freezing temperature (-18 degrees C) to plasma liquefaction temperature (2 degrees C to 8 degrees C).

3. Production of concentrated red blood cells with type O blood


From whole blood: Take 2 units of type O whole blood into the triple blood bag, centrifuge to separate 2 units of concentrated O red blood cell mass. From the red blood cell mass : Remove the red blood cell nutrients from 2 units of the O blood group. This work is only done when whole blood and red blood cells have been collected within 24 hours.

Khối hồng cầu mới cần được sử dụng ngay trong vòng 24 giờ
Khối hồng cầu mới cần được sử dụng ngay trong vòng 24 giờ

4. Mixing O blood group concentrate with AB . plasma


For frozen plasma (2 units of red blood cell mass + 1 unit of plasma): Use a blood transfusion line to put 1⁄2 units of AB frozen plasma into each unit of O concentrated red blood cell mass , then proceed to mix well. For fresh frozen plasma (2 units of red blood cell mass + 2 units of plasma): 1 unit of group O concentrated red blood cell mass is mixed with 1 unit of group AB fresh frozen plasma.

5. Do cross-reaction


Tube 1: The patient's serum + O blood group red blood cells Tube 2: The patient's red blood cells + AB plasma Vinmec International General Hospital is one of the hospitals that not only ensures professional quality with the team a team of leading medical doctors, a system of modern equipment and technology, but also outstanding with comprehensive and professional medical examination, consultation and treatment services; civilized, polite, safe and sterile medical examination and treatment space.
Customers can directly go to Vinmec Health system nationwide to visit or contact the hotline here for support.

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Indications for rational use of blood and blood products What do blood products include? Using blood and blood products
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