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Brospecta belongs to a group of antibiotics used to treat certain infections caused by bacteria, including otitis media, strep throat, pneumonia, urinary tract infections, and gonorrhea.1. What is Brospecta?
Brospecta is on the World Health Organization's list of essential medicines, containing the main ingredient Cefixime (as Cefixime trihydrate) 200mg. Brospecta belongs to the group of anti-viral, anti-bacterial, anti-fungal, anti-parasitic drugs.
2. What are the effects of Brospecta?
Brospecta is indicated for use in the following cases:
Treatment of uncomplicated urinary tract infections caused by susceptible bacteria such as Escherichia coli and Proteus mirabilis. Treatment of ear diseases: Otitis media caused by Haemophilus influenzae, Moraxella catarrhalis and Streptococcus pyogenes. Throat diseases such as tonsillitis and pharyngitis caused by Streptococcus pyogenes. Treatment of some diseases related to the chest and lungs: Chronic bronchitis caused by Streptococcus pneumoniae and Haemophilus influenzae. Cervical and urethral diseases: Gonorrhea (cervical, urethral) caused by susceptible isolates of Neisseria gonorrhoeae (penicillinase-producing and non-penicillinase-producing isolates). Skin and soft tissue infections: Active against group A and B beta-hemolytic streptococci. Brospecta is also used to treat typhoid fever. Note:
Cefixime ingredient in the drug belongs to the Cephalosporin antibiotic group. It works by preventing the growth of pathogenic bacteria. This antibiotic only treats bacterial infections and Brospecta will not be effective in treating viral infections such as the common cold or flu. Cefixime is not recommended for use in patients who are sensitive or allergic to the cephalosporin group of antibiotics. Brospecta should not be used in children under 6 months of age. It is not recommended to use the drug in people with a history of severe penicillin allergy
3. Dosage and how to take Brospecta
Usage:
Brospecta-200 is prepared in the form of hard capsules, used orally, can be used during or after meals. The usual duration of treatment is 7-14 days depending on the severity of the disease. Dosage:
For adults:
The recommended dose is 200-400mg/day, depending on the degree of infection, can be taken once or divided into 2 doses 12 hours apart. Uncomplicated gonorrhea 400mg dose. For patients with renal failure: Adjust dosage according to creatinine clearance. Specifically as follows:
If Creatinine clearance is over 60ml/min, no dose adjustment is required, apply as normal dose. If the creatinine clearance is from 21 to 60 ml/min, the dose is 300 mg/day. If the creatinine clearance is less than 20 ml/min, the dosage is 200 mg/day. For children:
Children over 12 years old and weighing over 50kg: Use the same recommended dose as adults. For children over 6 months to 12 years old, the dose is 8mg/kg/day, taken once or divided into two doses 12 hours apart.
4. Side effects of Brospecta
Common side effects when using drugs such as digestive disorders: Diarrhea, abdominal pain, nausea, vomiting, flatulence, loss of appetite, pseudomembranous colitis. Affects the nervous system with symptoms of headache, dizziness, restlessness, poor sleep, body fatigue. Causes hypersensitivity reactions such as erythema, urticaria, drug fever, rash, urticaria, erythema, the drug must be discontinued and appropriate measures instituted. Hematologic reactions include granulocytopenia or eosinophilia, but these reactions are rare. Renal Effects: Periodic monitoring of renal function is recommended, as patients with severe renal impairment such as acute renal failure have been reported. Vitamin deficiency: Vitamin K deficiency manifests as hypoprothrombinemia or leads to bleeding easily; lack of B vitamins with manifestations of neuritis, glossitis, stomatitis, loss of appetite. One of the rare reactions to the use of Brospecta is an intestinal reaction caused by a bacteria called C. difficile. This symptom may occur during or after the patient has stopped treatment. Tell your doctor right away if you experience related symptoms such as: Diarrhea that doesn't stop, stomach/stomach pain, cramps, blood/mucus in the stool. Long-term or repeated use of this medicine may lead to new oral thrush or vaginal yeast infections. Patients need to inform their doctor about unwanted side effects while using the drug.
5. Be careful when using Brospecta
Brospecta should be used with caution in the following cases:
With patients with renal failure, including patients on extra-renal dialysis. The patient has a history of gastrointestinal disease and colitis. For pregnant women: There are not enough data to prove that the drug is safe for pregnant women. Therefore, in this case, use Cefixime only when absolutely necessary and prescribed by a doctor. Use with caution in nursing women because the drug may affect the development of the newborn. Therefore, the mother should temporarily stop breastfeeding while taking the drug.
6. Drug interactions
Drug interactions can affect the effectiveness of treatment or increase the risk of serious side effects. Therefore, patients should be aware that some drugs that can interact with Brospecta include:
Probenecid: When combined with Brospecta, it will increase the peak concentration and AUC of Cefixime, decrease the renal clearance and the volume of feces. father of the drug. Anticoagulants: Increases prothrombin time with or without bleeding. Effects on test results: This medication may cause false positive results in some tests on diabetic urine (cupric sulfate type). Carbamazepine: Risk of increased plasma concentration of Carbamazepine. Nifedipine: Increases the availability of Cefixime. Above is information about uses, dosage and precautions when using Brospecta. To ensure safety for your health and maximize the effectiveness of your treatment, you need to take Brospecta exactly as directed by your doctor.
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