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Pariet 20mg drug belongs to the group of digestive drugs with the main ingredient being Rabeprazole sodium, which is commonly used to treat gastric and duodenal ulcers, anastomotic ulcers, reflux esophagitis and Zollinger-Ellison syndrome. However, the drug can also cause certain side effects that patients need to be aware of.
1. Uses of Pariet tablets 200mg
Pariet 20mg drug with the main ingredient is rabeprazole, which inhibits gastric secretion both basal and stimulated by inhibiting the enzyme H + / K + - ATPase in the parietal cells of the gastric mucosa. The mechanism of action of pariet is as follows:
Enzyme H + / K + - ATPase is considered to pump acid, hydrogen or proton in the cell, so rabeprazole is considered a proton pump inhibitor. Rabeprazole is therefore able to bind to this enzyme blocking the final stage of gastric secretion. The anti-ulcer effect of Rabeprazole sodium is quite strong against many types of ulcers and improves gastric mucosal lesions. Pariet 20mg is usually indicated in the following cases:
Active peptic ulcer Benign gastric ulcer Anastomotic ulcer Gastroesophageal reflux disease ulcerative or erosive form (GERD) Maintenance treatment of GERD Symptomatic treatment of moderate to severe GERD Zollinger-Ellison syndrome and other pathological hypersecretory conditions In combination with an appropriate antibacterial regimen to eradicate Helicobacter Pylori in patients with peptic ulcers contraindicated in patients allergic to rabeprazole, benzimidazole derivatives or any of the ingredients in pariet 20mg.
2. Dosage of the drug pariet 20mg
Pariet 20mg drug is usually used orally, the patient must not chew or break the tablet, should take it at least 30 minutes before eating to promote the full effect of the drug. Depending on the treatment goal, the dose of pariet will be different:
Treatment of acute duodenal ulcer: 20mg/time/day in the morning, orally for 4 weeks if the ulcer is not completely healed Treat stomach ulcer Acute stomach: 20mg / time / day x 6 weeks in the morning, if the ulcer has not healed, continue to use for another 6 weeks Treatment of gastroesophageal reflux disease with symptoms of ulcers, scratches: 20 mg / time / day x 4-8 weeks Symptomatic treatment of gastroesophageal reflux disease without esophagitis: 10 mg once daily for up to 4 weeks then 10 mg once daily as needed Zollinger-Ellison syndrome: initial with a dose of 60 mg/time/day, up to a maximum of 120 mg/day, divided into 2 doses depending on the patient, may appoint a dose of once/day up to 100 mg.
3. Side effects of the drug pariet 20mg
In some patients when using pariet, side effects may occur such as:
Fever, chills Chest pain Increased liver enzymes Restlessness, drowsiness Sore throat, rhinitis, cough Urinary tract infection Muscle pain, joint pain, cramps Insomnia, headache, dizziness Dry mouth, belching Itching, erythema Back pain, weakness Diarrhea, nausea, abdominal pain, constipation, flatulence
4. Be careful when using pariet 20mg:
Some general precautions when using pariet 20mg are:
Patients should be monitored periodically when treatment lasts more than 1 year with rabeprazole Do not use pariet in young children The possibility of malignancy should be excluded. Pre-treatment There have been reports of hematopoietic disorders (thrombocytopenia and neutropenia) with rabeprazole and resolved upon discontinuation of unknown cause Particular caution should be exercised when using pariet for patients with severe hepatic impairment, as there are insufficient clinical data in this patient population Use of pariet may increase the risk of gastrointestinal infections with Salmonella, Campylobacter and clostridium difficile when administered rabeprazole to patients without Inherited galactose intolerance or impaired absorption of glucose, galactose Pariet 20mg drug belongs to the group of digestive drugs with the main ingredient being Rabeprazole sodium, commonly used to treat gastric and duodenal ulcers, stomatitis, esophagitis. reflux and Zollinger-Ellison syndrome. To ensure effective treatment and avoid unwanted side effects, patients need to take the drug exactly as directed by a doctor or pharmacist.
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