Should pregnant women with hepatitis B, C, HIV have amniocentesis and chorionic villus biopsies?

This is an automatically translated article.

The article is professionally consulted by Master, Doctor Nguyen Thi Hong On - Department of Obstetrics and Gynecology - Vinmec Phu Quoc International General Hospital.
Some prenatal screening procedures require deep penetration into the uterus to obtain tissue samples and amniotic fluid samples for testing, such as amniocentesis and chorionic villus biopsies. So, for mothers infected with hepatitis B, hepatitis C, HIV-infected mothers can amniocentesis?

1. What is amniocentesis and chorionic villus biopsies?

Amniocentesis: Under ultrasound guidance, amniotic fluid is drawn through the abdominal wall with a very fine needle. This amniotic fluid sample will carry out the necessary diagnostic tests. The amount of amniotic fluid that needs to be taken is 15 - 30 ml. Amniocentesis is performed at >16 weeks gestation.
Chorionic villus Biopsy: A chorionic villus biopsy is the removal of a small amount of placental tissue from the uterus of a pregnant woman. The vesicle sample will be obtained with a needle or catheter through the abdomen. During the chorionic villus biopsy procedure, the pregnant woman will be numbed to relieve pain and relieve stress. The collected vegetable cake samples are considered and taken to carry out necessary diagnostic tests. Chorionic villus biopsies were performed at 12-14 weeks of gestation with a favorable placental position.

2. Purpose of amniocentesis and chorionic villus biopsies

Prenatal diagnostic tests are necessary to help the doctor know if the fetus has genetic abnormalities and infections. Usually these tests are done based on amniocentesis, chorionic villus biopsies.
The results of amniocentesis and chorionic villus biopsies will reveal genetic problems before birth, so that parents can plan appropriate care and treatment after the baby is born or with certain treatable diseases. treat the baby before birth. In some cases of severe birth defects, difficult to treat before and after birth, parents may decide to terminate the pregnancy after consulting the doctor with the results to reduce the burden on the family and society.

3. Pregnant women with hepatitis B, hepatitis C, HIV should have a biopsy and amniocentesis?

Mothers with hepatitis B can have amniocentesis is a question of many pregnant women infected with this disease. In fact, the risk of mother-to-child transmission of the virus in pregnant women with hepatitis B after amniocentesis is quite low. However, a viral load of HBV DNA > 7log10 copies/ml may increase the risk of mother-to-child transmission of hepatitis B.
For pregnant women with hepatitis C, amniocentesis or chorionic villus sampling does not increase the risk of mother-to-child transmission of the virus. However, for pregnant women with HIV, chorionic villus sampling and amniocentesis may increase the risk of transmission (particularly in pregnant women who do not receive antenatal viral load reduction therapy).

4. Notes after performing cholecystectomy and amniocentesis

Some women will have mild abdominal pain after amniocentesis, the doctor will give oral medication and the pregnant woman should rest on the day of amniocentesis, the next day the abdominal pain will decrease. Pregnant women should rest for about 24 hours, avoiding heavy work.

Carry out normal activities and bathing, do not abstain from water. Re-examination immediately when you see signs of severe abdominal pain, vaginal discharge, vaginal bleeding, high fever. Pregnant women come to get the results of amniocentesis or chorionic villus sampling according to the doctor's appointment, where the doctor will consult the results and have instructions for the next antenatal visit. For more information, please contact the hospitals and clinics of Vinmec health system nationwide.

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