This is an automatically translated article.
Any pregnant woman wants her baby to be born with the most fully developed and healthy body. However, in cases of premature birth, the baby may have respiratory problems because the lungs are not fully developed. In order to stimulate the lungs to mature early in cases of preterm birth, the doctor may advise the family of pregnant women to give fetal lung support injections.
1. What is a lung maturation drug?
Premature birth often leads to complications such as fetal death, neonatal mortality, respiratory distress syndrome, systemic infection, cerebral hemorrhage. In which, to prevent respiratory failure for premature babies, doctors often appoint pregnant women to inject preventive drugs to mature the lungs. Currently, the commonly used lung maturation drugs, also known as lung aids, are Dexamethasone and Betamethasone belonging to the corticosteroid group, which promote lung maturation in the fetus.
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2. By what mechanism does the lung maturation drug work?
Lung support drugs, after being injected into pregnant women, will be transmitted through the bloodstream and affect the lungs of the fetus. Pulmonary stimulants increase the ability of the lungs to convert pneumocytes I into pneumocytes II, stimulate the production of surfactant, which has the effect of reducing the surface tension of the cystic fluid layer and resisting the elastic force of the lungs. Medicines work to increase lung volume and reduce the amount of fluid in the lungs.
After 12 hours of injection of lung support medicine, the blood sugar level in the pregnant woman's blood increases slightly for about 5 days, so the mother should be screened for diabetes before injecting the drug. If a pregnant woman has gestational diabetes, she should stay in the hospital for monitoring to avoid possible dangerous complications.
Sau khi tiêm thuốc trợ phổi, đường huyết thai phụ sẽ tăng
3. When should lung support injections be given?
Lung maturation drugs are usually given at 24-34 weeks of pregnancy. Repeat injection after 7 days if there is a risk of preterm birth. Especially after 34 weeks, there is no need to inject lung support drugs anymore because they are no longer effective for children.
Dosage for lung maturation injection:
Betamethasone 12mg (Diprospan (5+2)mg): Intramuscular 2 times, each dose 24 hours apart. Dexamethasone 6mg: 4 doses intramuscularly, 12 hours apart.
4. Should you inject drugs to support fetal lung during pregnancy?
Not all pregnant women need to inject drugs to support the fetus's lungs because the fetus, if it is full week, will fully develop the internal organs in the body so that after birth, it can adapt immediately to the environment. living.
Mature pregnancy is counted as full 37 weeks from the first day of the last menstrual period. Births from 22 weeks to before 37 weeks are counted as premature births. In cases of premature birth, the fetus has not had enough time to fully develop some internal organs, especially the lungs. Therefore, cases of risk of preterm birth or threatened preterm birth are often recommended by doctors to use lung support drugs to avoid respiratory complications for the baby.
Signs of threat of preterm birth:
Water rupture Low back pain with cramps Abdominal cramps with diarrhea Painful uterine contractions (at least 2 in 1 hour). There may be blood or pink mucus in the vagina. There is a change in the cervix (only known by examination or ultrasound)
Thuốc trợ phổi được sử dụng cho những trường hợp sinh non
Signs to identify pregnant women at risk of preterm birth:
Maternal risk: Pregnant women with a history of cervical cone resection, preterm birth in previous births, uterine malformations, uterine fibroids, pregnant women having a short cervix, opening the uterus, stitching the cervix, ... Risks in the fetus: fetal growth retardation, preeclampsia, rupture of membranes or amniotic fluid, multiple pregnancy, placenta previa, placenta In general, pregnant women at risk of premature birth should inject lung support drugs to prevent respiratory complications from premature birth, healthy pregnant women can also inject fetal lung support drugs during pregnancy if possible. to ensure the all-round development of the child. However, healthy pregnant women should consider and consult a doctor before deciding to inject lung support drugs because lung support drugs can cause some bad side effects for both mother and baby.
5. Some unwanted side effects when using lung maturation drugs
Lung maturation drugs are listed in Group C by the US Food and Drug Administration. Group C drugs are a group that can have side effects when using them.
The following are some side effects of lung support drugs:
Increases the risk of infections in the mother such as fetal infection, postpartum infection... There is a risk of gestational diabetes The fetus has slow weight gain. , early craniosynostosis, the fetus is less active. Some harmful effects on the brain, adrenal gland, and pituitary gland of the fetus. Some reactions after injection such as shock or increased blood pressure, so care must be taken to use the correct dose of the drug Children are likely to become hyperactive if more than 3 doses of lung support are injected Injecting lung maturation is very important important in reducing complications of preterm infants, especially respiratory failure. The drug used to inject lung maturation has certain side effects, so before injecting, pregnant women should consult a doctor.
To protect the health of pregnant women and their babies during pregnancy, Vinmec International General Hospital provides a package maternity service as a solution to help pregnant women feel secure because of the companionship of the medical team. doctor during pregnancy. When choosing Maternity Package, pregnant women can:
The pregnancy process is monitored by a team of highly qualified doctors Regular check-ups, early detection of abnormalities The Package Maternity package helps to facilitate convenient for the birthing process Newborns get comprehensive care
Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.
