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Bricanyl is an injectable medication, used to relieve spasms in bronchial asthma, chronic bronchitis, emphysema and other lung diseases associated with bronchospasm.
1. What is Bricanyl?
Bricanyl drug main ingredient is Terbutaline - active ingredient in the group of beta-2 receptor stimulants, capable of bronchodilator and uterine muscle relaxant. It also helps to reduce the clearance of the mucinous cilia in patients with chronic obstructive pulmonary disease. As a result, the bronchial mucus is thinner, making it easier to transport and expel mucus.
The drug Bricanyl has the effect of stopping bronchospasm in acute or subacute cases. At the same time, it helps to relax the smooth muscle of the uterus in threatened preterm labor.
After intravenous or subcutaneous administration, 90% of Bricanyl is excreted by the kidneys in 48-96 hours, about 60% of the drug is excreted unchanged.
2. Indications of the drug Bricanyl
Bricanyl is indicated in the following cases:
Bronchial asthma (acute exacerbation with bronchospasm); Chronic bronchitis (major bronchospasm); Emphysema ; Threatening to give birth prematurely. Wheezing, chest tightness, shortness of breath due to bronchospasm.
3. Contraindications of the drug Bricanyl
Contraindicated to use Bricanyl with people with hypersensitivity to the ingredients of the drug.
Note:
Drugs that increase sensitivity to sympathomimetic amines (hyperthyroidism have not been properly treated), use caution. Use caution when giving the drug to diabetics because it can increase blood sugar. Patients with severe myocardial ischemia, myocardial hypertrophy need a doctor's prescription when taking the drug. Monitor serum potassium when co-administered with xanthine derivatives, steroids, diuretics and when reducing inhaled air oxygen. Use for pregnant and lactating women requires a doctor's prescription and strict supervision.
4. Dosage and how to take Bricanyl
How to use: The dosage form of Bricanyl is solution for injection. Indications for intravenous / subcutaneous injection.
Dosage:
In case of bronchospasm:
Intravenous: Adults: 0.5 - 1 mL slow injection over 5 minutes, can be repeated after several hours, up to 2 mg/24 hours. Intravenous infusion: Adults: 1-2 mg/day, starting dose: 0.1 mg by slow intravenous infusion over 10 minutes. For children: 25 mcg/kg/day, starting dose: 1.5 mcg/kg, slow intravenous infusion over 10 minutes. Subcutaneous injection: Adults: 1⁄2 ampoules (0.5ml=0.25mg)/time/24 hours, divided into 4 times. In more severe disease, you can use 1 ampoule of 1ml (=0.5mg)/time. For children: 25 mcg/kg/day in at least 4 divided doses. In more severe disease can use 10mcg/kg/time (0.02ml/kg/time). In case of threatened preterm birth:
Dosage is individualized and limited by increases in heart rate and changes in blood pressure. During the first hour, the dose is 10 mcg/min (=40 drops/min according to dilution instructions). If contractions do not stop, the dose may be increased in increments of 5 mcg/min (= 20 drops/min according to dilution instructions) every 10 minutes. Maximum dose: 25mcg/min (100 drops/min according to dilution instructions). Thereafter, the dose may be reduced in increments of 5 mcg/min every half hour until the lowest dose is reached without reoccurrence of contractions. Treatment is by slow intravenous infusion for at least 8 hours, then maintenance therapy starts with 1 tablet (5mg)/ 17ml oral solution x 3 times/day. Use until the end of the 36th week of pregnancy.
5. Side effects of drugs
Using Bricanyl can cause some side effects such as:
Common:
Body as a whole: Headache; On the circulatory system: Palpitations; On the central nervous system: Restlessness; On the musculoskeletal system: Tremor, cramps/cramps of hands or feet. Rare:
Skin: Urticaria, rash. Metabolic disorders: Hypokalemia, hyperglycemia. Neuropsychiatric: Sleep disturbances and behavioral disturbances. In the treatment of threatened preterm birth: The paraclinical picture resembles pulmonary edema, increased propensity to uterine bleeding during caesarean section. Above is the complete information about the drug Bricanyl. Patients should carefully read the instructions for use before use.
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