Razadyne: Uses, indications and precautions when using

This is an automatically translated article.

Razadyne is used to treat memory loss associated with Alzheimer's disease. The drug does not work to cure Alzheimer's disease, but it can help improve memory, cognition, and the ability to perform daily functions. Razadyne works to restore the balance of certain neurotransmitters) in the brain.

1. Indications and contraindications of the drug Razadyne

Razadyne is indicated in the following cases:
Diffuse Lewy body dementia Mild to moderate dementia Moderate to severe Alzheimer's disease Razadyne is contraindicated in the following cases:
Atrioventricular block Heart rate slow QT change on ECG at birth Asthma Obstructive lung disease Duodenal ulcer Stomach or intestinal ulcer Liver disease Bladder obstruction Convulsions Moderate to severe renal impairment CYP2D6 poor metabolizer.

2. How to use Razadyne

Take Razadyne by mouth with food, usually twice daily at breakfast and dinner, or as directed by your doctor. Take the medicine with plenty of water unless otherwise directed. To reduce your risk of side effects, your dose of Razadyne will be gradually increased until your target dose is reached. Your dose is calculated based on your medical condition and response to therapy, up to 24 milligrams per day.
If you are using the liquid form of Razadyne, read the manufacturer's leaflet and follow the instructions exactly. Use the included measuring device to measure the dose of your medication. Mix the medicine with about 120ml of non-alcoholic beverage, stir and drink the whole mixture.
If you stop taking Razadyne for more than 3 days, your doctor may ask you to start it again at a low dose and gradually increase your dose to reduce your risk of side effects.
Use Razadyne medicine regularly to get the most benefit from it. Do not stop taking the medicine or increase the dose without your doctor's instructions.
It may take at least 4 weeks of use before Razadyne has its full effect. Inform your doctor if your condition worsens after using Razadyne.
Because Razadyne can cause loss of appetite and weight loss, your doctor should monitor your weight before and during treatment with this medicine.

3. Side effects of Razadyne

While using Razadyne, you may experience nausea, vomiting, diarrhea, dizziness, drowsiness, loss of appetite, and weight loss. If any of these Razadyne side effects persist or get worse, tell your doctor right away.
Remember that your doctor has prescribed this medicine for you because he or she has judged that the benefit to you is greater than the risk of side effects. Many people use Razadyne without any serious side effects.
Tell your doctor right away if you have any serious side effects of Razadyne, including: Fainting, unusually slow heartbeat, trouble urinating.
Get medical help right away if you have any very serious side effects of Razadyne, including: Convulsions, black/bloody stools, bloody or coffee-ground-like vomit, pain severe stomach or stomach pain, irregular heartbeat.
A very serious allergic reaction to Razadyne is very rare. However, if you notice any symptoms of a serious allergic reaction to Razadyne, including: rash, itching or swelling (especially of the face/tongue/throat), dizziness, trouble breathing, Get medical help right away.
Below are Razadyne side effects by likelihood.
Common side effects of Razadyne include:
Dizziness Decreased appetite Weight loss Headache Nausea Vomiting Diarrhea Uncommon side effects of Razadyne include:
Depression Slow heart rate Indigestion Sadness Sleep Fainting Low energy Muscle tremor Body weakness Irritability Severe abdominal pain

Rare side effects of Razadyne include:
Dehydration Atrioventricular block QT interval prolongation on ECG Hepatitis Bladder Obstruction Erythema multiforme Stevens-Johnson syndrome Convulsions Extreme liver function tests Abnormal rhythm supraventricular tachycardia Acute exanthematous pustulosis Blurred vision Ringing in the ears High blood pressure Low blood pressure Muscle spasms Muscle weakness Hallucinations Excessive sweating Loss of taste Skin rash Temporary redness of face and neck Heart palpitations pounding Tingling sensation in the skin Deep sleep or long sleep This is not a complete list of Razadyne possible side effects. If you notice other side effects of Razadyne medicine not listed above, contact your doctor immediately for timely treatment.

4. Measures to prevent side effects of Razadyne

Before taking Razadyne, tell your doctor if you are allergic to this medicine or to daffodils and to any other allergies, if any. Razadyne products may contain ingredients that do not work, and they may cause allergic reactions or other problems.
Before using Razadyne medicine, consult your doctor if you have: Severe liver disease, severe kidney disease.
Before using Razadyne, tell your doctor your medical history, especially of: Liver problems, kidney problems, stomach/intestinal problems (e.g. stomach ulcers, stomach or intestinal bleeding), heart problems (such as slow heartbeat, arrhythmia), breathing/lung problems (such as severe asthma, COPD - chronic obstructive pulmonary disease), seizures , problems with urination.
Razadyne may make you dizzy or drowsy and alcohol or marijuana may make you more dizzy or drowsy. Do not drive, use machinery, or do anything that requires alertness while using Razadyne, until you can do so safely.
Before surgery, tell your doctor or dentist that you are taking Razadyne.
Razadyne should only be used when clearly needed during pregnancy and should be discussed with your doctor about the risks and benefits. Currently, it is not known whether Razadyne passes into breast milk, women who are breastfeeding should consult their doctor before use.

5. Razadyne drug interactions

Your doctor may already be aware of any possible drug interactions with Razadyne and may be monitoring you for it. Do not start, stop, or change the dose of any medicine during treatment with Razadyne without your doctor's consent.
Before using Razadyne, tell your doctor about all prescription and nonprescription/herbal medicines you may use, especially of: Anticholinergics (e.g. Atropine, diphenhydramine, scopolamine, tolterodine), high-dose aspirin used for arthritis, cholinergic drugs (eg, Bethanechol), cholinesterase inhibitors (such as Neostigmine), long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs such as ibuprofen, naproxen), medicines that affect the removal of galantamine from your body (such as azole antifungals including ketoconazole, amitriptyline, antidepressants including paroxetine, quinidine).
Also report the use of cardiac drugs (those that decrease heart rate or block AV impulse conduction) such as: Beta-blockers (including metoprolol, propranolol), digoxin.
Many medicines contain pain relievers/fever reducers (NSAIDs such as aspirin, ibuprofen or naproxen), which, if taken with Razadyne, may increase the risk of stomach/intestinal bleeding. However, you should continue to take low-dose aspirin, for specific medical reasons such as heart attack or stroke prevention.

6. What to do if you overdose or forget to take Razadyne?

If you or someone else has overdosed on Razadyne and has severe symptoms such as fainting or difficulty breathing, call 911 immediately. Symptoms of Razadyne overdose may include muscle weakness or seizures, severe stomach cramps, slow or shallow breathing, slow/fast/irregular heartbeat, fainting.
If you miss a dose of Razadyne, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose, take your next dose of Razadyne at the usual time, and do not double your usual dose.

7. How to store Razadyne

Store Razadyne at room temperature (25 degrees Celsius), protected from light and moisture. It is allowed to store for a short time from at a temperature of 15-30 degrees Celsius. Do not store in the bathroom, do not freeze the medicine, keep the medicine out of the reach of children and pets. Dispose of Razadyne appropriately when it has expired or is no longer needed by you.

Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.

Reference source: webmd.com