This is an automatically translated article.
The article was written by Doctor of Intensive Care Department - Vinmec Times City International General Hospital.
Recently, you often hear medical professionals, especially in the field of emergency resuscitation, or people mention the English term "sepsis bundle" which means "severe infection control package". So what is a severe infection control package? why is it called bundle - bundle? What is the first hour of sepsis treatment “Hour-1 sepsis bundle” and what does it mean for the patient? We will answer each of the above questions in turn.
1. What is a Sepsis bundle? and why is it called bundle - bundle?
In the United States every year, there are about 1.7 million cases of severe infection, also known as sepsis, and is the cause of death for about 250,000 people, accounting for about 30 - 50% of all hospital deaths. In Vietnam, there are no complete statistics, but it can be said that severe infections are the second leading cause of death after cardiovascular diseases.
Faced with that challenge in 2003 ICU specialists and infectious disease specialists from 11 medical professional organizations in the US and Europe met, after 2 years of building on Based on the research data conducted on sepsis patients, a set of "Guidelines for diagnosis and management of sepsis patients in 2005" have been developed - surviving sepsis campaign 2005 with the aim of increasing the rate of Mortality from severe sepsis falls by 25% within 5 years. This guide was later updated based on the results of later research with versions 2008, 2013 and 2018 with the names “surviving sepsis campaign 2008”, “surviving sepsis campaign 2013” and “surviving sepsis campaign 2018”.
Sepsis - tình trạng nhiễm trùng huyết trong y học
Full compliance with the contents of the above recommendations in clinical practice in the Emergency Departments and Intensive Care Units accounts for a very low rate, specifically, there are only a few Emergency Departments and ICUs The intensive care unit (ICU) can implement 100% of the recommendations and all results in improved mortality compared to the previous one. This has led scientists to find solutions to the problem of compliance with recommendations, there have been many studies focusing on a number of important groups of goals to be achieved, easy to implement and effective. high enough to make compliant Emergency and ICU departments applicable, including in low-resource departments (low-income countries), and from there the concept of “bundle” was born.
“Sepsis bundle” is a collection of diagnostic and therapeutic measures that need to be achieved within a certain time frame, specifically in the early 2010s, people divided into bundles of the first 3 hours as “sepsis resuscitation” package. bundle” and bundle for the next 6 hours is the severe infection management bundle “sepsis management bundle”.
2. What is the first 1 hour sepsis treatment package “Hour-1 sepsis bundle” and what does it mean for the patient?
On the basis of research results, applying the "surviving sepsis campaign 2012" recommendation for the treatment of severe infections 2012 to the treatment of patients with severe infection "sepsis" and septic shock "septic shock", 2019 sepsis bundle is changed according to the trend with 5 sepsis treatment goals that need to be achieved earlier in the first 1 hour “Hour-1 sepsis bundle” because it plays an important and decisive role in the mortality rate. However, complying with the 5 goals to be achieved in the first hour is still a challenge in the context of Vietnam's health sector due to many specific reasons.
Gói 1 giờ bắt đầu hồi sức sepsis và sốc nhiễm khuẩn
In 2019 with the help of Prof. Christ Farmer, former Head of ICU at Mayo Clinic (USA) and former President of Critical Care Medicine (SCCM), developed and routinely applied a treatment package for severe infections within the first hour. “Hour-1 sepsis bundle” and gave very positive initial results and promises to help improve the results and prognosis of severe infections at Vinmec Times City General Hospital in particular and the Vinmec Health System. Generally speaking.
