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Primary or premature ovarian failure occurs when the ovaries stop working properly before the age of 40, resulting in the ovaries not producing normal amounts of the hormone estrogen or releasing eggs regularly.
1. Symptoms of Primary Ovarian Failure
Primary ovarian insufficiency is sometimes confused with early menopause, but in reality, the two conditions are not the same. Women with primary ovarian insufficiency may have irregular or sporadic periods for many years and may even become pregnant, while women with early menopause stop menstruating and become unable to become pregnant. .Signs and symptoms of primary ovarian failure are similar to those of menopause or estrogen deficiency, including:
Irregular or absent menstrual periods, which may persist for years or present after pregnancy or after stopping birth control pills Difficulty getting pregnant or infertility Hot flashes Night sweats Vaginal dryness Dry eyes Irritability or difficulty concentrating Decreased sex drive If symptoms are not menstruating menstrual period for three or more months, see your doctor to determine the cause of this condition.
Bạn nên gặp bác sĩ để kiểm tra tình trạng sức khỏe nếu kinh nguyệt không đều
2. Causes of Primary Ovarian Failure
Primary ovarian failure can be caused by:
Chromosomal defects: Several genetic disorders are associated with primary ovarian failure, including Turner syndrome which causes a woman to have only one normal X chromosome. and the second X chromosome is changed and Fragile X Syndrome makes the X chromosome very fragile and fragile. Toxins: Chemotherapy and radiation therapy are common causes of toxin-induced ovarian failure. Because these therapies can damage the genetic material in cells. In addition, other toxins such as cigarette smoke, chemicals, pesticides, and viruses can accelerate ovarian failure. The immune system's response to ovarian tissue (autoimmune disease). In these rare forms, the body's immune system creates antibodies against the patient's own ovarian tissue, damaging the follicles and damaging the eggs. The cause of primary ovarian failure is often unknown or is called idiopathic. Although your doctor may prescribe imaging or laboratory techniques to find the cause, in many cases no cause can be found. Factors that increase the risk of developing primary ovarian failure include:
Age: The risk increases between the ages of 35 and 40. Although rare before age 30, primary ovarian failure can occur in young women and even in adolescents. Family history: If a close family member such as a grandmother, mother, older sister, or younger sister has primary ovarian insufficiency, your risk of developing this disorder increases. Ovarian surgery: Surgery involving the ovaries increases the risk of primary ovarian failure.
Tuổi tác ảnh hưởng trực tiếp đến nguy cơ phát triển suy buồng trứng nguyên phát
3. Effect of primary ovarian failure on fertility
One of the complications of primary ovarian failure is infertility. The ovaries are a pair of small oval-shaped organs in a woman's lower abdomen. About once a month, one of the ovaries releases an egg. The ovaries also make the hormones estrogen and progesterone. These components play this important role during pregnancy, menstrual cycle and breast development.
A woman with primary ovarian failure may have fewer eggs or the ovaries may not mature or release eggs normally. As a result, the ovaries do not produce normal amounts of hormones.
Primary ovarian failure is not the same as menopause. Menopause usually occurs around the age of 50. During the transition before menopause, the ovaries decrease in size and produce less hormones. This time is called perimenopause. At the time of menopause, the ovaries no longer have eggs, so there will be no monthly menstrual period. In contrast, women with primary ovarian failure can still have irregular or even normal menstrual cycles. And women with primary ovarian failure may still have eggs in their ovaries.
Currently, there is no proven effective treatment regimen to restore fertility in women with primary ovarian failure. Some women and their partners can get pregnant through in vitro fertilization using donor eggs. The procedure involves taking eggs from a donor and fertilizing them with your partner's sperm in a lab. The fertilized egg (embryo) is then placed in the patient's uterus.
Phụ nữ bị suy buồng trứng nguyên phát có thể mang thai nhờ thụ tinh trong ống nghiệm
Customers can come to the Center for Reproductive Support - Vinmec International General Hospital. This is the leading center in Vietnam, which has developed and applied a comprehensive medical examination and treatment process, combining both gynecology and obstetrics and gynecology to provide the optimal method for each patient's case.
Advantages when customers choose Vinmec fertility center:
Equipped with modern equipment, clean air system according to international standards to ensure lab quality, single cabinet system to optimize quality embryo, improving the success rate for each cycle of artificial insemination. Implement most advanced assisted reproductive techniques in the world: ICSI (injection of sperm into the oocyte cytoplasm); support embryo escape membrane; Reproductive reserve: embryo freezing, sperm freezing, oocyte freezing to help customers take the initiative in giving birth at will, transferring embryos on day 5, minimizing pregnancy; male infertility techniques (PESA, MESA, TEFNA, TESE) Besides advanced reproductive support methods, a team of excellent doctors in the country and the world, with prestige and long-term experience in the field of infertility .
Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.
References: mayoclinic.org, mayoclinic.org, acog.org/clinicalMORE
Premature ovarian failure, is it possible to get pregnant? What tests are needed to diagnose ovarian failure? Assisted reproductive techniques are performed at Vinmec Hospital
