This is an automatically translated article.
Article written by Doctor Ha Thi Lien - Vinmec High-Tech Center
Placental biopsy is a technique to remove the dendritic spines in the placenta to serve genetic tests for prenatal diagnosis. The placenta is biopsied vaginally or through the abdomen. Placental analysis can diagnose chromosomal abnormalities such as Down syndrome as well as other genetic diseases. Placental biopsies are of great significance in prenatal diagnosis.
1. In case of indication for placental biopsy
During pregnancy, the placenta is the place where metabolism is carried out and provides nutrients and oxygen for the developing fetus. The placental spines are villi fibers embedded in the placenta in the shape of comb teeth and share a common genetic origin with the fetus. A placental biopsy is done between 11 and 14 weeks of pregnancy.
Screening results: Double test, NIPT shows fetus at high risk of chromosomal abnormalities Ultrasound shows abnormal fetal morphology History of pregnancy with chromosomal abnormalities Wife or husband has chromosomal abnormalities may or may not carry an abnormal gene Other cases (family history of the spouse having a genetic disease, an elderly pregnant woman who wishes to be tested, a non-invasive screening test with abnormal results. ..) must have a consultation with the hospital prenatal diagnosis board
Contraindication of spine biopsy:
Pregnant women with HIV, advanced hepatitis B, hepatitis C Pregnant women with infection, acute toxicity Pregnant women with advanced medical diseases, internal diseases The secretions are not well controlled (diabetes, basedow) Pregnant women with autoimmune diseases (Lupus, positive Antiphospholipid syndrome) Old surgical scars with intestinal adhesions, bladder to the uterus, placenta biopsies performed from Early weeks of pregnancy should give quick results for the next appropriate indications for pregnant women. However, this technique still has invasive risks and the risk of miscarriage is about 0.2%.
The process of testing placental biopsy at the High-Tech Center, Vinmec International General Hospital:
Samples after biopsy are transferred to the High-Tech Center within 24 hours. Samples are specially processed in the laboratory. Test for molecular pathology and cytogenetics Test results for placental biopsies will be available within 7 days to 3 weeks. The antenatal patient undergoing the procedure will be counseled before the test and after the test results are available will be consulted by a geneticist and an obstetrician.
Vinmec International General Hospital is one of the hospitals that not only ensures professional quality with a team of leading medical doctors, modern equipment and technology, but also stands out for its examination and consultation services. comprehensive and professional medical consultation and treatment; civilized, polite, safe and sterile medical examination and treatment space. Customers when choosing to perform tests here can be completely assured of the accuracy of test results.
Customers can directly go to Vinmec Health system nationwide to visit or contact the hotline here for support.
Articles refer to sources: mayoclinic.org, hopkinsmedicine.org
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What is a chorionic villus biopsies? Is placenta calcification dangerous? When is the best time to do a chorionic villus biopsy?