Precautions while using Pulmicort Respules

This is an automatically translated article.


Posted by Pharmacist Nguyen Thu Giang - Clinical Pharmacist - Faculty of Pharmacy - Vinmec Times City International Hospital

Pulmicort Respules is an aerosol form with the main active ingredient being budesonide - an anti-inflammatory corticosteroid widely used in the treatment and prevention of bronchial asthma in adults and children. What should be noted when using Pulmicort Respules?

1. What is pulmicort respules?


Pulmicort respules is an aerosol form with the main active ingredient being budesonide. Usually, the drug is indicated for the treatment of bronchial asthma, acute croup (Crop's disease) in infants and children. In addition, pulmicort is used as an alternative therapy and to reduce the dose of oral steroids.

1. What is pulmicort respules?


Pulmicort respules is an aerosol form with the main active ingredient being budesonide. Usually, the drug is indicated for the treatment of bronchial asthma, acute croup (Crop's disease) in infants and children. In addition, pulmicort is used as an alternative therapy and to reduce the dose of oral steroids.

Thuốc pulmicort respules có tác dụng điều trị hen phế quản
Thuốc pulmicort respules có tác dụng điều trị hen phế quản

2. How to take Pulmicort respules


Pulmicort respules is an aerosol form, so patients are not given infusion, not taken orally. The drug pulmicort is prepared in a suspension form (which is a drug with solid particles that do not dissolve in a liquid solvent). Therefore, for proper use, pulmicort should be used with a pressure nebulizer, not with Ultrasonic nebulisers, because it may damage the medicine.
When aerosolizing, the patient will use with a mask or through an endotracheal tube to deliver the drug. It is possible to nebulize the drug undiluted, however, if you want to prolong the delivery time (more than 10 minutes) or reduce the number of aerosolization times (when multiple nebulizers are used), the drug can be mixed with sterile saline. common medicine, or some other drugs such as terbutaline, salbutamol, fenoterol, acetylcysteine, ipratropium bromide. This mixture should be used within 30 minutes. Opened vial should be used within 12 hours.
The composition of pulmicort respules is a corticosteroid, so the patient is at risk of fungal infection in the oropharynx due to the drug deposited at this location. Therefore, after each inhalation, the patient should rinse his mouth thoroughly with water. If using a mask, be sure to fit the mask being aerosolized and wash your face thoroughly after each application.
Pulmicort respules drugs need to be stored properly to ensure quality and safe to use. Accordingly, the drug should be protected from light by placing it in an aluminum blister. Currently, pulmicort respules is packaged in aluminum blisters consisting of 5 tubes, only one aluminum blister is opened at a time, 5 tubes are used up and then the next aluminum blister is opened. Besides, it is necessary to pay attention to store the medicine tray (with aluminum lid closed) in the box after use. In addition, after opening the aluminum blister, it should be noted:
Record the date of opening. Adding 3 months to the date of opening is the date when the blister pack needs to be discarded if all the tubes in it are not used up. Record the date the blister pack should be placed in the space provided on the aluminum cap and all tubes remaining in the unused blister pack should be discarded. Unlike many other drugs, pulmicort respules can still be used by pregnant and lactating women. However, the dose of pulmicort respules is quite variable and needs to be prescribed by a doctor. Therefore, to ensure the effectiveness of the patient, it is necessary to strictly follow the instructions and prescribed dosage of the doctor.

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Source: Vietnam National Pharmacopoeia 2015, Medicines.org.uk
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