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Oraptic 40mg is an injection, with the main ingredient Omeprazol 40mg, used in the treatment of a number of gastrointestinal diseases. Let's learn some notes when taking Oraptic 40mg through the article below.
1. What is Oraptic 40mg?
Oraptic 40mg is a gastrointestinal drug with a proton pump inhibitor function. Oraptic 40mg is prepared as lyophilized injection and is manufactured by Binh Dinh Pharmaceutical & Medical Equipment Company (BIDIPHAR) of Vietnam.1.1 Oraptic drug ingredients Main active ingredients: Omeprazole (Omeprazol sodium) ............ 40mg.
Ingredients contained in the solvent tube:
citric acid monohydrate ..................................................... .. 5mg. PEG 400 ....................................................................................... ......... 4g. Distilled water for injection e.g................................................. 10 ml. 1.2 Indications of Oraptic 40mg Oraptic 40mg is a prescription drug, prescribed by a specialist. Normally, Oraptic 40mg is used in the treatment of a number of medical conditions such as:
Patients with duodenal ulcer. Prevention of duodenal ulcer recurrence. Patients with stomach ulcers. Prevention of peptic ulcer recurrence. Combined with appropriate antibiotics to eliminate Helicobacter pylori (H. pylori) causing gastric ulcer disease. Stomach and duodenal ulcers caused by NSAIDs. Prevention of NSAID-induced gastric and duodenal ulcers in at-risk patients. Reflux esophagitis. Long-term control in healed patients with reflux esophagitis. Gastroesophageal reflux . Zollinger-Ellison syndrome. 1.3 Contraindication of Oraptic 40mg Oraptic 40mg is contraindicated in some cases as follows:
Patients with hypersensitivity to other Benzimidazoles such as: Etonitazene, Galeterone, Mavatrep, Dovitinib, Albendazole and Mebendazole,...or any any component of the drug. The patient has a malignant tumor. Women are breastfeeding.
2. Dosage and how to use Oraptic 40mg
Oraptic dosage is prescribed and guided by a specialist doctor or qualified pharmacist. Patients should adhere to the doctor's regimen to achieve high effectiveness in treatment.
2.1 Dosage of Oraptic 40 Dosage in adults when used orally is not effective:
40mg intravenously x 1 time / 24 hours for patients who cannot take the drug. Treatment of Zollinger - Ellison syndrome: Intravenous 60mg/day. In severe cases, the dose can be increased, depending on the body's response. In case of using a dose higher than 60mg/24 hours, it should be divided into 2 times/day. Dosage in patients with renal impairment:
No dose adjustment is required for patients with renal impairment. Dosage in patients with liver failure:
For patients with liver failure, a daily dose of 10-20mg can be applied. Dosage in the elderly (> 65 years old):
No need to adjust the dose for elderly subjects. Therapeutic doses in children:
Safety data on omeprazole are limited when used intravenously in children. 2.2 How to use Oraptic 40mg Dilute Oraptic with 10ml of solvent provided. Inject I.V (intravenously) slowly for at least 2.5 minutes at an injection rate not exceeding 4 ml/min. The solution after mixing should be used immediately or stored stably within 4 hours at a temperature of 25 degrees Celsius.
3. Side effects when taking Oraptic 40mg
During the use of Oraptic 40mg, the patient may appear some of the following symptoms:
Allergies, itching; Dizziness, nausea and diarrhea; Swelling – painful edema at the injection site; Leukopenia and increased liver enzymes; Angioedema, vomiting and headache; Digestive disorders and dry mouth. Note: Side effects of Oraptic 40mg can take place massively or individually depending on the location of each patient. Inform your doctor about the side effects you experience for timely treatment.
4. Oraptic 40mg . drug interactions
Oraptic 40mg may cause increased plasma concentrations of some drugs such as diazepam, phenyltoin and warfarin when used in combination. To avoid interactions, before being prescribed Oraptic 40mg, patients should inform their doctor about the drugs they are using. The doctor will base it on that to prescribe the appropriate Oraptic 40mg.
5. Some cautions to note when using Oraptic 40mg
Before and during the use of Oraptic for treatment, patients should refer to some notes when taking Oraptic 40mg as follows:
If there are symptoms of weight loss, vomiting, vomiting blood, black stools and difficulty swallowing or in the presence of gastric ulcer, the possibility of malignancy should be excluded. In the above case, using Oraptic can alleviate symptoms and delay diagnosis for patients. Omeprazole may reduce the absorption of vitamin B12 or lack of gastric acid. Therefore, Oraptic should be used with caution in patients with reduced body stores or risk factors for decreased absorption of vitamin B12 during long-term therapy. Omeprazole is an inhibitor of CYP2C19. Combining atazanavir with omeprazole is not recommended. If co-administration of these agents is required, close clinical supervision and increase the dose of atazanavir to 400 mg with 100 mg of ritonavir, while the dose of omeprazole should not exceed 20 mg. Therapeutic use of Omeprazole may result in a slightly increased risk of gastrointestinal infections such as Salmonella and Campylobacter. Severe hypomagnesemia occurred in patients treated with omeprazole for at least 3 months and in most cases when treated for 1 year. For cases requiring long-term treatment or the combination of Omeprazole with digoxin or drugs that can cause hypomagnesemia such as diuretics, it is necessary to perform laboratory tests to measure magnesium levels before and during treatment. Long-term (>1 year) use of high doses of Omeprazole may increase the risk of hip, wrist, and spine fractures, mainly in the elderly or with certain other risk factors. Omeprazole may affect CgA measurements: Intravenous omeprazole should be discontinued for at least 5 days prior to CgA measurement. If CgA and gastrin levels do not return to the reference range after the initial measurement, they should be measured again 14 days after stopping omeprazole therapy. Patients should be regularly monitored during long-term treatment, especially when the duration of omeprazole treatment exceeds 1 year. Patients taking Omeprazole should not drive or operate machinery if they experience dizziness. All information above is for reference only. The use of Oraptic 40mg must be under the guidance of a specialist doctor and a qualified pharmacist.
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